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Toward Disease-Modifying Therapies in Type 1 Diabetes: Focus on Teplizumab
Diabetes CareChantal Mathieu, Emily K Sims, Lucienne Chatenoud, Eddie A James, Mark A Atkinson, Kevan C Herold -
Building a blueprint for intra-tumoral microbial studies
Nat MedJayanth Jawahar, Allyson L Byrd -
Reframing Residual Inflammatory Pathways in Pediatric Asthma-Reply
JAMA PediatrMatthew C Altman, Daniel J Jackson -
Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma
Nat CommunEdward Z Song, Andrea Timpanaro, Michael Meechan, Leonel Elena-Sanchez, Lucy Z Li, Sophie Jamet, Davina S Lau, Lily I Winter, Matthew D Dun, Jessica B Foster, Myron K Evans, Siobhan S Pattwell, Vandana Kalia, Surojit Sarkar, Michael C Jensen, Matthew C Biery, Nicholas A Vitanza -
Type 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort
J Allergy Clin Immunol GlobNaresh Doni Jayavelu, Jingjing Qi, Carly E Milliren, Al Ozonoff, Shanshan Liu, Ofer Levy, Lindsey R Baden, Esther Melamed, Grace A McComsey, Charles B Cairns, Joanna Schaenman, Albert C Shaw, David A Hafler, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough , William B Messer, Bali Pulendran, Kari C Nadeau, Mark M Davis, Linda N Geng, Ana Fernandez Sesma, Viviana Simon, Florian Krammer, Chris Bime, Carolyn S Calfee, Steven E Bosinger, Walter Eckalbar, Hanno Steen, Holden T Maecker, IMPACC Network, Alison D Augustine , Joann Diray-Arce, Elias K Haddad, Rafick-Pierre Sekaly, Monica Kraft, Prescott G Woodruff, David J Erle, Lauren I R Ehrlich, Ruth R Montgomery, Patrice M Becker, Matthew C Altman, Slim Fourati -
T Cell Autocrine Hyaluronan Forms Complex Structures in CD4 T Cell Cytoplasm and Plays a Critical Role in Formation of the Immune Synapse
J Histochem CytochemRobert B Vernon, Michel D Gooden, John A Gebe, Inkyung Kang, Caroline Stefani, Gail Workman, Adam Lacy-Hulbert, Paul L Bollyky, Thomas N Wight -
Rapid and label-free isolation of human peripheral blood monocytes using a reversible CD36-binding aptamer for cell capture
Biomaterials ScienceMelissa Ling, Nataly Kacherovsky, Abe Y Wu, Minjian Ni, Jessica A Hamerman, Suzie H Pun -
Multi-omic profiling reveals age-related immune dynamics in healthy adults
NatureQiuyu Gong, Mehul Sharma, Marla C Glass, Emma L Kuan, Aishwarya Chander, Mansi Singh, Lucas T Graybuck, Zachary J Thomson, Christian M LaFrance, Samir Rachid Zaim, Tao Peng, Lauren Y Okada, Palak C Genge, Katherine E Henderson, Elisabeth M Dornisch, Erik D Layton, Peter J Wittig, Alexander T Heubeck, Nelson M Mukuka, Julian Reading, Garrett Strawn, Teminijesu Titus-Adewunmi, Kathleen Abadie, Charles R Roll, Veronica Hernandez, Vaishnavi Parthasarathy, Tyanna J Stuckey, Blessing Musgrove, Elliott Swanson, Cara Lord, Morgan D A Weiss, Cole G Phalen, Regina R Mettey, Kevin J Lee, John B Johanneson, Erin K Kawelo, Jessica Garber, Upaasana Krishnan, Megan Smithmyer, E John Wherry, Laura A Vella, Sarah E Henrickson, Mackenzie S Kopp, Adam K Savage, Lynne A Becker, Paul Meijer, Ernest M Coffey, Jorg J Goronzy, Mikael Sigvardsson, Cate Speake, Thomas F Bumol, Ananda W Goldrath, Troy R Torgerson, Xiao-Jun Li, Peter J Skene, Jane H Buckner , Claire E Gustafson -
Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation
Sci Transl MedZiyuan He, Marla C Glass, Pravina Venkatesan, Marie L Feser, Leander Lazaro, Lauren Y Okada, Nhung T T Tran, Yudong D He, Samir Rachid Zaim, Christy E Bennett, Padmapriyadarshini Ravisankar, Elisabeth M Dornisch, Alexandra C Ferrannini, Najeeb A Arishi, Ashley G Asamoah, Saman Barzideh, Lynne A Becker, Elizabeth A Bemis, Jane H Buckner , Christopher E Collora, Megan A L Criley, Kristen Demoruelle M, Chelsie L Fleischer, Jessica Garber, Palak C Genge, Qiuyu Gong, Lucas T Graybuck, Claire E Gustafson, Brian C Hattel, Veronica Hernandez, Alexander T Heubeck, Erin K Kawelo, Upaasana Krishnan, Emma L Kuan, Kristine A Kuhn, Christian M LaFrance, Kevin J Lee, Ruoxin Li, Cara Lord, Regina R Mettey, Laura Moss, Blessing Musgrove, Katherine Hy Nguyen, Andrea Ochoa, Vaishnavi Parthasarathy, Mark-Phillip Pebworth, Chong Pedrick, Tao Peng, Cole G Phalen, Julian Reading, Charles R Roll, Jennifer A Seifert, Marguerite D Siedschlag, Cate Speake, Christopher C Striebich, Tyanna J Stuckey, Elliott G Swanson, Hideto Takada, Tylor Thai, Zachary J Thomson, Nguyen Trieu, Vlad Tsaltskan, Wei Wang, Morgan D A Weiss, Amy Westermann, Fan Zhang, David L Boyle, Ananda W Goldrath, Thomas F Bumol, Xiao-Jun Li, V Michael Holers, Peter J Skene, Adam K Savage, Gary S Firestein, Kevin D Deane, Troy R Torgerson, Mark A Gillespie -
Generative Design of Antibody Fc-variants with Synthetic and Programmable Functional Profiles
bioRxivIrvine EB, Bikias T, Stamkopoulos E, Frei L, Schürmann N, Warrender AK, Schmid H, Coukos D, Yang H, Minot M, Kelton W, Reddy ST -
Neutrophil-enriched gene signature correlates with teplizumab therapy resistance in different stages of type 1 diabetes
J Clin InvestGabriele Sassi, Pierre Lemaitre, Laia Fernández Calvo, Francesca Lodi, Álvaro Cortés Calabuig, Samal Bissenova, Amber Wouters, Laure Degroote, Marijke Viaene, Niels Vandamme, Lauren Higdon, Peter S Linsley, S Alice Long, Chantal Mathieu, Conny Gysemans -
T-cell responses against CD19-targeted CAR T cells varnimcabtagene autoleucel (ARI-0001): implications for immune response and therapy outcomes
J Immunother CancerAriadna Bartoló-Ibars, Andrea Aran, Alexandra M Johansson, Valentín Ortiz-Maldonado, Nela Klein-González, Anna Alonso-Saladrigues, Eddie James, Alvaro Urbano-Ispizua, Susana Rives, Julio Delgado, Europa Azucena González-Navarro, William W Kwok, Manel Juan -
ATG as disease-modifying therapy for new-onset type 1 diabetes
LancetCate Speake -
A multi-omics recovery factor predicts long COVID in the IMPACC study
J Clin InvestGisela Gabernet, Jessica Maciuch, Jeremy P Gygi, John F Moore, Annmarie Hoch, Caitlin Syphurs, Tianyi Chu, Naresh Doni Jayavelu, David B Corry, Farrah Kheradmand, Lindsey R Baden, Rafick-Pierre Sekaly, Grace A McComsey, Elias K Haddad, Charles B Cairns, Nadine Rouphael, Ana Fernandez-Sesma, Viviana Simon, Jordan P Metcalf, Nelson I Agudelo Higuita, Catherine L Hough , William B Messer, Mark M Davis, Kari C Nadeau, Bali Pulendran, Monica Kraft, Chris Bime, Elaine F Reed, Joanna Schaenman, David J Erle, Carolyn S Calfee, Mark A Atkinson, Scott C Brakenridge, Esther Melamed, Albert C Shaw, David A Hafler, Alison D Augustine , Patrice M Becker, Al Ozonoff, Steven E Bosinger, Walter Eckalbar, Holden T Maecker, Seunghee Kim-Schulze, Hanno Steen, Florian Krammer, Kerstin Westendorf, IMPACC Network, Bjoern Peters, Slim Fourati, Matthew C Altman, Ofer Levy, Kinga K Smolen, Ruth R Montgomery, Joann Diray-Arce, Steven H Kleinstein, Leying Guan, Lauren I R Ehrlich -
Mepolizumab alters gene regulatory networks of nasal airway type-2 and epithelial inflammation in urban children with asthma
Nat CommunCourtney L Gaberino, R Max Segnitz, Kimberly A Dill-McFarland, Leonard B Bacharier, Agustin Calatroni, Michelle A Gill, Jeffrey Stokes, Andrew H Liu , Robyn T Cohen, Rajesh Kumar, Abigail Lang, Gurjit K Khurana Hershey, Michael G Sherenian, Edward M Zoratti, Stephen J Teach, Meyer Kattan , Patrice M Becker, Alkis Togias, William W Busse, Daniel J Jackson, Matthew C Altman
