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Mar 2025
The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner.
Front ImmunolStock AJ, Gonzalez Paredes P, de Almeida LP, Kosanke SD, Chetlur S, Budde H, Wakenight P, Zwingman TA, Rosen ABI, Allenspach EJ, Millen KJ, Buckner JH, Rawlings DJ, Gorman JA -
Mar 2025
From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL-33.
Clin Transl ImmunologyObata-Ninomiya K, Jayaraman T, Ziegler SF -
Mar 2025
Antigen-specific immunotherapies for autoimmune disease.
Nat Rev RheumatolBuckner JH -
Mar 2025
Urinary proteomics identifies distinct immunological profiles of sepsis associated AKI sub-phenotypes.
Crit CareStanaway IB, Morrell ED, Mabrey FL, Sathe NA, Bailey Z, Speckmaier S, Lo J, Zelnick LR, Himmelfarb J, Mikacenic C, Evans L, Wurfel MM, Bhatraju PK -
Mar 2025
Efficacy and Safety of Dupilumab in Children With Peanut Allergy: A Multicenter, Open-Label, Phase II Study.
AllergySindher SB, Nadeau KC, Chinthrajah RS, Leflein JG, Bégin P, Ohayon JA, Ponda P, Wambre E, Liu J, Khokhar FA, Akinlade B, Maloney J, Orengo JM, Hamilton JD, Kamal MA, Hooper AT, Patel N, Patel K, Laws E, Mannent LP, Radin AR -
Mar 2025
Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy.
AllergyChinthrajah RS, Sindher SB, Nadeau KC, Leflein JG, Spergel JM, Petroni DH, Jones SM, Casale TB, Wang J, Carr WW, Shreffler WG, Wood RA, Wambre E, Liu J, Akinlade B, Atanasio A, Orengo JM, Hamilton JD, Kamal MA, Hooper AT, Patel K, Laws E, Mannent LP, Adelman DC, Ratnayake A, Radin AR -
Mar 2025
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.
bioRxivMaguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH, IMPACC Network, Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E -
Mar 2025
Cytokine signatures in post-endoscopic retrograde cholangiopancreatography pancreatitis: a pilot study.
Ann GastroenterolMachicado JD, Lee PJ, Culp S, Stello K, Hart PA, Ramsey M, Lacy-Hulbert A, Speake C, Cruz-Monserrate Z, Elmunzer BJ, Whitcomb DC, Papachristou GI -
Nov 2024
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis.
RMD OpenTurcinov S, Sharma RK, De Vries C, Cîrciumaru A, Gerstner C, Mathsson-Alm L, Raposo B, Dubnovitsky A, Rönnblom L, Kwok WW, Chemin K, Malmström V, Hensvold A -
Nov 2024
B cell adapter for PI 3-kinase (BCAP) coordinates antigen internalization and trafficking through the B cell receptor.
Sci AdvLagos J, Holder U, Sagadiev S, Montiel-Armendariz A, Li LZ, Pasare C, Hou B, Hamerman JA, Acharya M -
Nov 2024
Synovial regulatory T cells expressing ST2 deteriorate joint inflammation through the suppression of immunoregulatory eosinophils.
J AutoimmunHattori K, Tanaka S, Hashiba D, Tamura J, Etori K, Kageyama T, Ito T, Meguro K, Iwata A, Suto A, Suzuki K, Nakamura J, Ohtori S, Ziegler SF, Nakajima H -
Nov 2024
An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy.
Cell RepJamison BL, Lawrance M, Wang CJ, DeBerg HA, Ziegler LJ, Sansom DM, Gavin MA, Walker LSK, Campbell DJ -
Nov 2024
Antigen-specific T-cell frequency and phenotype mirrors disease activity in DRB1*04:04+ rheumatoid arthritis patients.
Clin Exp ImmunolRims C, Uchtenhagen H, Brooks K, Ng B, Posso SE, Carlin J, Kwok WW, Buckner JH, James EA -
Nov 2024
Epigenetic trajectory predicts development of clinical rheumatoid arthritis in ACPA+ individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA).
bioRxivPrideaux EB, Boyle DL, Choi E, Buckner JH, Robinson WH, Holers VM, Deane KD, Firestein GS, Wang W -
Oct 2024
Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy.
J AutoimmunTewari R, Yang SJ, McClain ED, Hu A, Mortensen E, DeSchmidt A, Chen J, Kancharla A, Singh AK, James EA, Burman BE, Siddique A, Rawlings DJ, Patel C, Cerosaletti K, Buckner JH