-
TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation
EMBO RepThomas E Schultz, Carmen D Mathmann, Leslie C Domínguez Cadena, Timothy W Muusse, Hyoyoung Kim, James W Wells, Glen C Ulett, Jessica A Hamerman, Andrew J Brooks, Bostjan Kobe, Matthew J Sweet, Katryn J Stacey, Antje Blumenthal -
Rheumatoid arthritis - the role of T cells in this complex systemic autoimmune disease.
Curr Opin ImmunolSavvides CS, James EA, Buckner JH -
T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblasts
J Invest DermatolHannah A DeBerg, Mitch L Fahning, Suraj R Varkhande, James D Schlenker, William P Schmitt, Aayush Gupta, Archana Singh, Iris K Gratz, Jeffrey S Carlin, Daniel J Campbell, Peter A Morawski -
Pancreatic enzyme replacement therapy in advanced adenocarcinoma of the pancreas improved overall survival: a retrospective, single institution study
OncologistVincent J Picozzi, Margaret T Mandelson, Anas Najjar, Moming Li, Diala E Harb, Jens J Kort -
Mapping the developmental profile of ventricular zone-derived neurons in the human cerebellum
Proc Natl Acad Sci U S AAnders W Erickson, Henry Tan, Liam D Hendrikse, Jake Millman, Zachary Thomson, Joseph Golser, Omar Khan, Guanyi He, Kathleen Bach, Arpit Suresh Mishra, Janja Kopic, Zeljka Krsnik, Ferechte Encha-Razavi, Giulia Petrilli, Fabien Guimiot, Evelina Silvestri, Kimberly A Aldinger, Michael D Taylor, Kathleen J Millen, Parthiv Haldipur -
A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection.
CellWestfall S, Gentile ME, Olsen TM, Karo-Atar D, Bogza A, Röstel F, Pardy RD, Mandato G, Fontes G, Herbert D, Melichar HJ, Abadie V, Richer MJ, Vinh DC, Koenig JFE, Harrison OJ, Divangahi M, Weis S, Gregorieff A, King IL -
Type 1 Diabetes TrialNet: Leading the Charge in Disease Prediction, Prevention, and Immunotherapeutic Mechanistic Understanding
Diabetes CareLaura M Jacobsen, Jamie L Felton, Brandon M Nathan, Cate Speake, Jeffrey Krischer, Kevan C Herold -
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection
Trends in BiotechnologyI Deniz Derman, Mecit Altan Alioglu, Joseph Christakiran Moses, Zissis C Chroneos , Yasar Ozer Yilmaz, Dishary Banerjee, Jonathan Koff, Syed Hasan Askari Rizvi, Danielle Nicole Klunk, Nazmiye Celik, Sirisha Pochareddy, Todd M Umstead, Ilayda Namli , Sarah E Holton, Carmen Mikacenic, Jessica L Thompson, Diana Cadena Castaneda, Danielle Reifsnyder Hickey, Momoka Nagamine, Prajakta Warang, Michael Schotsaert, Phylip Chen, Mark E Peeples, Karolina Palucka, Ibrahim T Ozbolat -
Long-term outcome of rendezvous internalization treatment for external pancreatic fistulas associated with disconnected pancreatic duct syndrome: a retrospective study
surgical endoscopyHyung Ku Chon, Richard A Kozarek, Mehran Fotoohi, Shayan S Irani -
Reduced Function of the Adaptor SH2B3 Promotes T1D via Altered Cytokine-Regulated, T-Cell-Intrinsic Immune Tolerance.
DiabetesWatson TK, Rosen ABI, Drow T, Medjo JA, MacQuivey MA, Ge Y, Liggitt HD, Grosvenor DA, Dill-McFarland KA, Altman MC, Concannon PJ, Buckner JH, Rawlings DJ, Allenspach EJ -
Two DRB3 residues predictively associate with the progression to type 1 diabetes among DR3 carriers
JCI InsightLue Ping Zhao, George K Papadopoulos , Jay S Skyler, William W Kwok, George P Bondinas, Antonis K Moustakas, Ruihan Wang , Chul-Woo Pyo , Wyatt C Nelson , Daniel E Geraghty, Åke Lernmark -
Distinct roles for thymic stromal lymphopoietin (TSLP) and IL-33 in experimental eosinophilic esophagitis
AllergyAnish Dsilva, Ariel Wagner , Michal Itan, Natalie Rhone , Shmulik Avlas, Yaara Gordon, Natalie Davidian , Shraddha Sharma, Elizaveta Razravina , Israel Zan-Bar , Jane R Parnes, Kevin S Gorski , Joseph D Sherrill, Chen Varol , Steven F Ziegler , Marc E Rothenberg , Ariel Munitz -
Longitudinal single cell profiling of epitope specific memory CD4+ T cell responses to recombinant zoster vaccine
Nat CommunXiaomin Wen, Alex K Hu, Emily S Ford, David M Koelle, William W Kwok, +Presnell SR -
A molecular basis for milk allergen immune recognition in eosinophilic esophagitis.
J Allergy Clin ImmunolDilollo J, Hu A, Qu H, Canziani KE, Clement RL, McCright SJ, Shreffler WG, Hakonarson H, Spergel JM, Cerosaletti K, Hill DA -
A coding single nucleotide polymorphism in the interleukin-6 receptor enhances IL-6 signalling in CD4 T cells and predicts treatment response to tocilizumab in giant cell arteritis.
Ann Rheum DisZorc R, Redmond C, Sylvester M, Maclean M, Yamamoto de Almeida L, Quinn KA, Tomelleri A, Campochiaro C, Dagna L, Gutierrez-Rodrigues F, Wells KV, Rankin C, Hait SH, Palmer C, Corty R, Bick A, Lambert K, Buckner JH, O'Shea JJ, Park JK, Gadina M, Grayson PC