-
Mar 2025
Reduced function of the adaptor SH2B3 promotes T1D via altered cytokine-regulated, T cell intrinsic immune tolerance
DiabetesTaylor K Watson, Aaron B I Rosen, Travis Drow, Jacob A Medjo, Matthew A MacQuivey, Yan Ge, H Denny Liggitt , Dane A Grosvenor , Kimberly A Dill-McFarland , Matthew C Altman, Patrick J Concannon, Jane H Buckner , David J Rawlings 1, Eric J Allenspach -
Mar 2025
Two DRB3 residues predictively associate with the progression to type 1 diabetes among DR3 carriers
JCI InsightLue Ping Zhao, George K Papadopoulos , Jay S Skyler, William W Kwok, George P Bondinas, Antonis K Moustakas, Ruihan Wang , Chul-Woo Pyo , Wyatt C Nelson , Daniel E Geraghty, Åke Lernmark -
Mar 2025
Distinct roles for thymic stromal lymphopoietin (TSLP) and IL-33 in experimental eosinophilic esophagitis
bioRxivAnish Dsilva, Ariel Wagner , Michal Itan, Natalie Rhone , Shmulik Avlas, Yaara Gordon, Natalie Davidian , Shraddha Sharma, Elizaveta Razravina , Israel Zan-Bar , Jane R Parnes, Kevin S Gorski , Joseph D Sherrill, Chen Varol , Steven F Ziegler , Marc E Rothenberg , Ariel Munitz -
Mar 2025
Longitudinal single cell profiling of epitope specific memory CD4+ T cell responses to recombinant zoster vaccine
Nat CommunXiaomin Wen, Alex K Hu, Scott R Presnell, Emily S Ford, David M Koelle, William W Kwok -
Mar 2025
A molecular basis for milk allergen immune recognition in eosinophilic esophagitis.
J Allergy Clin ImmunolDilollo J, Hu A, Qu H, Canziani KE, Clement RL, McCright SJ, Shreffler WG, Hakonarson H, Spergel JM, Cerosaletti K, Hill DA -
Mar 2025
A coding single nucleotide polymorphism in the interleukin-6 receptor enhances IL-6 signalling in CD4 T cells and predicts treatment response to tocilizumab in giant cell arteritis.
Ann Rheum DisZorc R, Redmond C, Sylvester M, Maclean M, Yamamoto de Almeida L, Quinn KA, Tomelleri A, Campochiaro C, Dagna L, Gutierrez-Rodrigues F, Wells KV, Rankin C, Hait SH, Palmer C, Corty R, Bick A, Lambert K, Buckner JH, O'Shea JJ, Park JK, Gadina M, Grayson PC -
Mar 2025
A systematic review of machine learning-based prognostic models for acute pancreatitis: Towards improving methods and reporting quality.
PLoS MedCritelli B, Hassan A, Lahooti I, Noh L, Park JS, Tong K, Lahooti A, Matzko N, Adams JN, Liss L, Quion J, Restrepo D, Nikahd M, Culp S, Lacy-Hulbert A, Speake C, Buxbaum J, Bischof J, Yazici C, Evans-Phillips A, Terp S, Weissman A, Conwell D, Hart P, Ramsey M, Krishna S, Han S, Park E, Shah R, Akshintala V, Windsor JA, Mull NK, Papachristou G, Celi LA, Lee P -
Mar 2025
Considerations for more actionable consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes. Reply to Mallone R [letter].
DiabetologiaPhillip M, Achenbach P, Addala A, Albanese-O'Neill A, Battelino T, Bell KJ, Besser REJ, Bonifacio E, Colhoun HM, Couper JJ, Craig ME, Danne T, de Beaufort C, Dovc K, Dutta S, Ebekozien O, Elding Larsson H, Frohnert BI, Gallagher MP, Greenbaum CJ, Griffin KJ, Hagopian W, Haller MJ, Hendriks E, Holt RIG, Ismail HM, Jacobsen LM, Kolb LE, Kordonouri O, Lange K, Lash RW, Lernmark A, Libman I, Lundgren M, Maahs DM, Marcovecchio ML, Mathieu C, Oron T, Patil SP, Rewers MJ, Rich SS, Schatz DA, Schulman-Rosenbaum R, Simmons KM, Sims EK, Skyler JS, Speake C, Steck AK, Tonyushkina KN, Veijola R, Wentworth JM, Wherrett DK, Wood JR, Ziegler AG, DiMeglio LA -
Mar 2025
Defining a novel DYRK1A-gp130/IL-6R-pSTAT axis that regulates Th17 differentiation.
ImmunohorizonsMalueg M, Moo KG, Arnett A, Edwards TH, Ruskin SL, Lambert K, Subramanyam A, Dufort MJ, Gersuk VH, Partridge R, Buckner JH, Khor B -
Mar 2025
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling.
ImmunityOgishi M, Kitaoka K, Good-Jacobson KL, Rinchai D, Zhang B, Wang J, Gies V, Rao G, Nguyen T, Avery DT, Khan T, Smithmyer ME, Mackie J, Yang R, Arias AA, Asano T, Ponsin K, Chaldebas M, Zhang P, Peel JN, Bohlen J, Lévy R, Pelham SJ, Lei WT, Han JE, Fagniez I, Chrabieh M, Laine C, Langlais D, Gruber C, Al Ali F, Rahman M, Aytekin C, Benson B, Dufort MJ, Domingo-Vila C, Moriya K, Shlomchik M, Uzel G, Gray PE, Suan D, Preece K, Chua I, Okada S, Chikuma S, Kiyonari H, Tree TI, Bogunovic D, Gros P, Marr N, Speake C, Oram RA, Béziat V, Bustamante J, Abel L, Boisson B, Korganow AS, Ma CS, Johnson MB, Chamoto K, Boisson-Dupuis S, Honjo T, Casanova JL, Tangye SG -
Mar 2025
Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection.
bioRxivLabuda JC, Olsen TM, Verma S, Kimmel S, Edwards TH, Dufort MJ, Harrison OJ -
Mar 2025
Proteomic Analyses in COVID-19-Associated Secondary Hemophagocytic Lymphohistiocytosis.
Crit Care ExplorCanny SP, Stanaway IB, Holton SE, Mitchem M, O'Rourke AR, Pribitzer S, Baxter SK, Wurfel MM, Malhotra U, Buckner JH, Bhatraju PK, Morrell ED, Speake C, Mikacenic C, Hamerman JA -
Mar 2025
Dysregulation of airway and systemic interferon responses promotes asthma exacerbations in urban children.
J Allergy Clin ImmunolGaberino CL, Altman MC, Gill MA, Bacharier LB, Gruchalla RS, O'Connor GT, Kumar R, Khurana Hershey GK, Kattan M, Liu AH, Teach SJ, Zoratti EM, Becker PM, Togias A, Visness C, Gern JE, Busse WW, Jackson DJ -
Mar 2025
Identification of bronchial epithelial genes associated with type 2 eosinophilic inflammation in asthma.
J Allergy Clin ImmunolEsnault S, Dill-McFarland KA, Altman MC, Rosenkranz MA, Jarjour NN, Busse WW -
Mar 2025
Novel T Cell reactivities to Hybrid Insulin Peptides in Islet Autoantibody-Positive At-Risk Subjects.
DiabetesHohenstein AC, Gallegos J, Dang M, Groegler J, Broncucia H, Tensun F, Waugh K, Dong F, James EA, Speake C, Steck AK, Rewers MJ, Gottlieb PA, Haskins K, Delong T, Baker RL