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Candida in the lower respiratory tract induces barrier disruption in mice and predicts poor outcomes in mechanically ventilated humans
PNAS USANathanial J Tolman, Wonseok Choi, Riley Coulter, Mark E Snyder, Lokesh Sharma, Shulin Qin, Eric D Morrell, Carmen Mikacenic, Jonathan K Alder, Xiaohong Wang, Mohammadreza Tabary, Yingze Zhang, Kyle Inman, Noel Britton, Barbara Methe, Panayiotis V Benos, Jessica Bon, Keven Robinson, Charles Dela Cruz, M Hong Nguyen, Alison Morris, Partha S Biswas, William Bain, Georgios D Kitsios -
IL-2 mutein selectively expands thymic memory Tregs with increased transendocytosis activity in healthy participants
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Specificity, frequency, and phenotype of citrullinated-specific T cells vary with disease activity in rheumatoid arthritis
JCI InsightCliff Rims, Hannah A DeBerg, Sylvia E Posso, Virginia S Muir, Hannes Uchtenhagen, Anne M Hocking, Heather Bukiri, Jeffrey Carlin, Bernard Ng, Peter S Linsley, Eddie A James, Jane H Buckner -
Autoantibodies and T Cells Target Citrullinated and Homocitrullinated Antigens in Rheumatoid Arthritis
Immunological ReviewsEddie A James, Aïsha Callebaut, Jane H Buckner, William W Kwok -
From data to discovery: a unified framework for human immunology
Nature ImmunologyRuth R Montgomery, Matthew C Altman, Daniel Rotrosen, Bali Pulendran, Nadine Rouphael, Frances E Lund -
International consensus guidance for general population screening for islet autoantibodies to diagnose early-stage type 1 diabetes: a nominal group technique process
DiabetologiaAnette-Gabriele Ziegler, Marian J Rewers, Peter Achenbach, Kirstine J Bell, Ezio Bonifacio, Linda A DiMeglio, Sanjoy Dutta, Helena Elding Larsson, Brigitte I Frohnert, Kurt J Griffin, William A Hagopian, Laura M Jacobsen, Karin Lange, Roberto Mallone, Parth Narendran, Tal Oron, Stephen S Rich, Caitrin W McDonough, Darja Šmigoc Schweiger, Zdenek Šumník, Agnieszka Szypowska, Riitta Veijola, Jurgen Vercauteren, John M Wentworth, Diane K Wherrett, Anastasia Albanese-O'Neill -
Lessons learned from clinical trials of thymic stromal lymphopoietin inhibition
The Journal of Allergy and Clinical ImmunologyJonathan Corren, Larry Borish, Christopher Brightling, Joseph K Han, Emma Guttman-Yassky, Steven Ziegler, Jean Publicover, Jyotsna Gulati, Nestor Molfino, Christopher S Ambrose, Jean-Pierre Llanos, Lang Chen, Jane R Parnes, Joseph Spahn, Andrew Lindsley -
Infants who develop bronchopulmonary dysplasia have an airway endotype defined by vimentin expression and ciliary loss
American Journal of Respiratory Cell and Molecular BiologyLaurie C Eldredge, Yan Han, Gail H Deutsch, Jennifer M S Sucre, Shawyon P Shirazi, Caroline Stefani, Stephan Pribitzer, Stephen R Reeves, Lucille M Rich, Elizabeth R Vanderwall, Steven F Ziegler, Jason S Debley -
A regulatory T cell-biased IL-2 mutein inhibits the development of allergen-specific Th2 cells and allergic asthma
The Journal of Allergy and Clinical ImmunologyAmandine Selle, Alexis Yero, James J Moon, Daniel J Campbell, Andrew D Luster -
Quantification of Proinsulin in Human Plasma by Proteolysis-Aided Peptide Immunoaffinity-Liquid Chromatography-Tandem Mass Spectrometry
Clinical ChemistrySara K Shijo, Elisha Goonatilleke, Lili Barahona-Carrillo, Katrina Forrest, Jessica O Becker, Michael J MacCoss, Cate Speake, Cecilia S Lee, Lisa Johnson, Huu-Hien Huynh, Andrew N Hoofnagle -
Citrullination and Deamidation in Type 1 Diabetes: Linking Beta Cell Stress to Neoantigen-Driven Autoimmunity
Immunological ReviewsAïsha Callebaut, Ylke Bruggeman, Chantal Mathieu, Eddie A James, Lut Overbergh -
Virus reactivation in acute and long COVID-19
NatureCole Maguire, Jing Chen, Nadine Rouphael, Brinkley A Morse, Annmarie Hoch, Harry Pickering, Hoang Van Phan, Abigail Glascock, Victoria Chu, Ravi Dandekar, IMPACC Network, David Corry, Farrah Kheradmand, Lindsey R Baden, Rafick-Pierre Sekaly, Grace A McComsey, Elias K Haddad, Charles B Cairns, Bali Pulendran, Ana Fernandez-Sesma, Viviana Simon, Jordan P Metcalf, Nelson I Agudelo Higuita, William B Messer, Mark M Davis, Kari C Nadeau, Monica Kraft, Chris Bime, Joanna Schaenman, David Erle, Carolyn S Calfee, Mark A Atkinson, Scott C Brakenridge, Lauren I R Ehrlich, Ruth R Montgomery, Albert Shaw, Catherine L Hough, David Hafler, Alison D Augustine, Patrice M Becker, Bjoern Peters, Al Ozonoff, Seunghee Kim-Schulze, Florian Krammer, Steven E Bosinger, Walter Eckalbar, Matthew C Altman, Michael Wilson, Leying Guan, Steven H Kleinstein, Kinga K Smolen, Elaine F Reed, Ofer Levy, Holden Maecker, Peter Hunt, Hanno Steen, Joann Diray-Arce, Charles R Langelier, Esther Melamed -
Rhinovirus and interleukin-13 alter DNA methylation in bronchial epithelial cells at asthma loci
ERJ Open ResearchWeston T Powell, R Max Segnitz, Lucille M Rich, Elizabeth R Vanderwall, Camille R Gates, Maria P White, Carole Ober, Matthew C Altman, Jason S Debley -
Innate Immune Cell and Epithelial Subsets Coordinate Airway Responses to Allergen
American Journal of Respiratory Cell and Molecular BiologyRyan C Murphy, Cecilia López-Martínez, Tristan Kooistra, Ying Lai, Matthew Liu, Patricia C Dela Cruz, Weston T Powell, Basilin Benson, Melissa Krueger, Jehan Alladina, Josalyn L Cho, Adrian M Piliponsky, Jason S Debley, Roma Sehmi, Gail M Gauvreau, Benjamin D Medoff, Sina A Gharib, Teal S Hallstrand -
A head-to-head comparison of abatacept and adalimumab in adults with early and dual seropositive rheumatoid arthritis plus HLA-DRB1 shared epitope: results from the randomised phase 3 AMPLIFIED trial
Annals of the Rheumatic DiseasesPaul Emery, Michael E Weinblatt, Vivian P Bykerk, Andrew P Cope, Yoshiya Tanaka, Gustavo Citera, Peter Nash, Gerd R Burmester, Quentin Dornic, Sheila Kelly, Nathanial Eddy, Jinqi Liu, Peter Schafer, Jane Buckner, Michael A Maldonado
