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Oct 2025
Neutrophil-enriched gene signature correlates with teplizumab therapy resistance in different stages of type 1 diabetes
J Clin InvestGabriele Sassi, Pierre Lemaitre, Laia Fernández Calvo, Francesca Lodi, Álvaro Cortés Calabuig, Samal Bissenova, Amber Wouters, Laure Degroote, Marijke Viaene, Niels Vandamme, Lauren Higdon, Peter S Linsley, S Alice Long, Chantal Mathieu, Conny Gysemans -
Oct 2025
T-cell responses against CD19-targeted CAR T cells varnimcabtagene autoleucel (ARI-0001): implications for immune response and therapy outcomes
J Immunother CancerAriadna Bartoló-Ibars, Andrea Aran, Alexandra M Johansson, Valentín Ortiz-Maldonado, Nela Klein-González, Anna Alonso-Saladrigues, Eddie James, Alvaro Urbano-Ispizua, Susana Rives, Julio Delgado, Europa Azucena González-Navarro, William W Kwok, Manel Juan -
Oct 2025
ATG as disease-modifying therapy for new-onset type 1 diabetes
LancetCate Speake -
Oct 2025
A multi-omics recovery factor predicts long COVID in the IMPACC study
J Clin InvestGisela Gabernet, Jessica Maciuch, Jeremy P Gygi, John F Moore, Annmarie Hoch, Caitlin Syphurs, Tianyi Chu, Naresh Doni Jayavelu, David B Corry, Farrah Kheradmand, Lindsey R Baden, Rafick-Pierre Sekaly, Grace A McComsey, Elias K Haddad, Charles B Cairns, Nadine Rouphael, Ana Fernandez-Sesma, Viviana Simon, Jordan P Metcalf, Nelson I Agudelo Higuita, Catherine L Hough , William B Messer, Mark M Davis, Kari C Nadeau, Bali Pulendran, Monica Kraft, Chris Bime, Elaine F Reed, Joanna Schaenman, David J Erle, Carolyn S Calfee, Mark A Atkinson, Scott C Brakenridge, Esther Melamed, Albert C Shaw, David A Hafler, Alison D Augustine , Patrice M Becker, Al Ozonoff, Steven E Bosinger, Walter Eckalbar, Holden T Maecker, Seunghee Kim-Schulze, Hanno Steen, Florian Krammer, Kerstin Westendorf, IMPACC Network, Bjoern Peters, Slim Fourati, Matthew C Altman, Ofer Levy, Kinga K Smolen, Ruth R Montgomery, Joann Diray-Arce, Steven H Kleinstein, Leying Guan, Lauren I R Ehrlich -
Oct 2025
Mepolizumab alters gene regulatory networks of nasal airway type-2 and epithelial inflammation in urban children with asthma
Nat CommunCourtney L Gaberino, R Max Segnitz, Kimberly A Dill-McFarland, Leonard B Bacharier, Agustin Calatroni, Michelle A Gill, Jeffrey Stokes, Andrew H Liu , Robyn T Cohen, Rajesh Kumar, Abigail Lang, Gurjit K Khurana Hershey, Michael G Sherenian, Edward M Zoratti, Stephen J Teach, Meyer Kattan , Patrice M Becker, Alkis Togias, William W Busse, Daniel J Jackson, Matthew C Altman -
Sep 2025
Loss of the actin remodeling protein Flightless-1 impairs CD8 and regulatory T cell function
bioRxivMichelle M Lissner, Jenna M Sullivan, Minjian Ni, McKenna Sherve, Anne M Hocking, Jessica A Hamerman, Daniel J Campbell -
Sep 2025
Profiling associations of interactive ligand-receptors (HLA class I and KIR gene products) with the progression to type 1 diabetes among seroconverted participants
DiabetologiaLue Ping Zhao, George K Papadopoulos , Benjamin J McFarland, Jay S Skyler, Hemang M Parikh, William W Kwok, Terry P Lybrand, George P Bondinas, Antonis K Moustakas, Ruihan Wang , Chul-Woo Pyo , Wyatt C Nelson , Daniel E Geraghty, Åke Lernmark -
Sep 2025
Screening Lessons from Prediction and Prevention of Type 1 Diabetes
Inflamm Bowel DisCate Speake, Adam Lacy-Hulbert, James Lord, Carla Greenbaum -
Sep 2025
TSLP: contrasting roles in cancer
Front ImmunolRemo Poto, Gianni Marone, Steven F Ziegler , Gilda Varricchi -
Aug 2025
Prevalence and severity of chronic kidney disease in a population with type 1 diabetes from a United States health system: a real-world cohort study
Lancet Reg Health AmKatherine R Tuttle, Christina L Reynolds, Lindsey M Kornowske, Cami R Jones, Radica Z Alicic, Kenn B Daratha, Joshua J Neumiller, Carla Greenbaum, Meda E Pavkov, Fang Xu, O Kenrik Duru, Susanne B Nicholas, Keith C Norris, CURE-CKD Consortium -
Aug 2025
MICBG406A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury
JCI InsightHarry Pickering, Narges Alipanah-Lechner, Ernie Chen, Dylan Duchen, Holden T Maecker, Seunghee Kim-Schulze, Ruth R Montgomery, Chris Cotsapas, Hanno Steen, Florian Krammer, Charles R Langelier, Ofer Levy, Lindsey R Baden, Esther Melamed, Lauren Ir Ehrlich, Grace A McComsey, Rafick P Sekaly, Charles B Cairns, Elias K Haddad, Albert C Shaw, David A Hafler, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough , William B Messer, Bali Pulendran, Kari C Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Monica Kraft, Chris Bime, David J Erle, Joanna Schaenmann, Al Ozonoff, Bjoern Peters, Steven H Kleinstein, Alison D Augustine , Joann Diray-Arce, Patrice M Becker, Nadine Rouphael, Matthew C Altman, Steve Bosinger, Walter Eckalbar, IMPACC Network, Carolyn S Calfee, Oscar A Aguilar, Elaine F Reed, John R Greenland, Daniel R Calabrese -
Aug 2025
Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in children
Am J Hum GenetEmma E Thompson, Xiaoyuan Zhong, Peter Carbonetto, Andréanne Morin, Jason Willwerscheid, Cynthia M Visness, Leonard B Bacharier, Meyer Kattan , George T O'Connor, Katherine Rivera-Spoljaric, Robert A Wood, Diane R Gold, Gurjit K Khurana Hershey, Christine C Johnson, Rachel L Miller, Christine M Seroogy, Edward M Zoratti, Peter J Gergen, Albert M Levin, Matthew C Altman, Tina Hartert, Matthew Stephens, Daniel J Jackson, James E Gern, Christopher G McKennan, Carole Ober -
Aug 2025
Inflammatory Pathways in Residual Asthma Exacerbations Among Mepolizumab-Treated Urban Children: A Secondary Analysis of a Randomized Clinical Trial
JAMA PediatrMatthew C Altman, Tomasz Janczyk, Ryan C Murphy, Naresh Doni Jayavelu, Agustin Calatroni, Meyer Kattan , Michelle A Gill, Jeffrey Stokes, Andrew H Liu , Gurjit K Khurana Hershey, Michael Sherenian, Rajesh Kumar, Rachel G Robison, Rebecca S Gruchalla, George T O'Connor, Edward M Zoratti, Stephen J Teach, Susan V Lynch, Kimberly A Dill-McFarland, Patrice M Becker, Alkis Togias, James E Gern, Leonard B Bacharier, William W Busse, Daniel J Jackson, Inner City Asthma Consortium and Childhood Asthma in Urban Settings Network -
Aug 2025
cytoKernel: robust kernel embeddings for assessing differential expression of single-cell data
BioinformaticsTusharkanti Ghosh, Ryan M Baxter, Souvik Seal, Victor G Lui, Pratyaydipta Rudra, Thao Vu, Elena W Y Hsieh, Debashis Ghosh -
Aug 2025
Single-cell transcriptomic profiling of eosinophils and airway immune cells in childhood asthma
J Allergy Clin ImmunolNaresh Doni Jayavelu, Andrew H Liu , Courtney Gaberino, Kristy Freeman, Matthew Lawrance, Stephan Pribitzer, Clara Seifert, Cullen Dutmer, Alkis Togias, Patrice M Becker, William W Busse, Christine A Sorkness, Carmen Mikacenic, Kimberly A Dill-McFarland, Daniel J Jackson, Matthew C Altman