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Jul 2025
Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications.
Front ImmunolCheng Z, Wang LJ, Honaker Y, Cincotta SA, Page CE, Vollhardt S, Yuan V, Long SA, Xiao Y, Beilke JN, Arron JR, Bluestone JA -
Jul 2025
Immunization with full-length TprC variants induces a broad response to surface-exposed epitopes of the Treponema pallidum repeat protein family and is partially protective in the rabbit model of syphilis.
VaccineGiacani L, Romeis E, Haynes A, Molini BJ, Tantalo LC, Xu LH, Trejos AT, Keane J, Mohamed Z, Armstrong TD, Wieland BA, Phung Q, Vyshenska D, Campbell VL, Godornes C, Koelle DM, Reid TB, Wang Y, Vorobieva AA, Wald A, Lieberman NAP, Greninger AL -
Jul 2025
A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency.
Cell RepCabrera-Martinez B, Garcia-Perez JE, Baxter RM, Lui VG, Ghosh T, Eken A, Kostka-Newman Z, Garcia JRM, Rahkola J, Gessner RL, Dutmer CM, Klarquist J, Pietras EM, Ghosh D, Johnson SA, Kedl RM, Hsieh EWY -
Jun 2025
Longitudinally stable T cell function and innate immune activation distinguish healthy adult immunotypes.
Sci Transl MedSmithmyer ME, Hu A, Dufort MJ, Hocking AM, Wiedeman AE, Fasano KJ, Torgerson TR, Skene PJ, Reading J, Li X, Gong Q, Long SA, Lacy-Hulbert A, Gustafson CE, Buckner JH, Speake C, members of the BRI Sound Life Project Team, BRI Sound Life Project Team -
Jun 2025
Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites
J Allergy Clin Immunol GlobThomas Kayser, Ronald Smulders, Tomohiro Kusawake, Erik Wambre, Gurunadh R Chichili, Mary B Blauwet, Anna Spence, Melanie Patton, Rima Tabash, Hannah A DeBerg, Sugandhika Khosa, Philipp Badorrek, Jens M Hohlfeld, Brian C Ferslew -
Jun 2025
Long-term outcome of rendezvous internalization treatment for external pancreatic fistulas associated with disconnected pancreatic duct syndrome: a retrospective study
Surg EndoscHyung Ku Cho, Richard A Kozarek, Mehran Fotoohi, Shayan S Irani -
Jun 2025
Functional dissection of noncoding variants associated with rheumatoid arthritis
Ann Rheum DisAjay Jajodia, Arpit Mishra, Naresh Doni Jayavelu, Katharina Lambert, Nicholas Moss, Zongchen Yang, Karen Cerosaletti, Jane H Buckner , R David Hawkins -
Jun 2025
Open access online calculator predicts peanut allergic reactions with high accuracy
J Allergy Clin Immunol PractHanipah Mears, Shriya A Sanghera, Henry T Bahnson, Ru-Xin Foong, Tom Marrs, Helen A Brough, Gideon Lack, George Du Toit, Alexandra F Santos -
Jun 2025
Latent EBV enhances the efficacy of anti-CD3 mAb in Type 1 diabetes
Nat CommunAna Lledó-Delgado, Paula Preston-Hurlburt, Lauren Higdon, Alex Hu, Eddie James, Noha Lim, S Alice Long, James McNamara, Hai Nguyen, Elisavet Serti, Tomokazu S Sumida, Kevan C Herold -
May 2025
Ara h 2105-124-Specific TH2A Cells Drive Peanut Allergy in DRB1*15:01 Individuals: A Detailed Epitope Analysis
Clin Exp AllergyRebecca A Gomez, Jue Hou, Vivian H Gersuk, I-Ting Chow, Mary L Farrington, David Robinson, William W Kwok -
Apr 2025
Pharmacotherapeutic strategies to promote regulatory T cell function in autoimmunity.
Curr Opin ImmunolWright RC, Campbell DJ, Levings MK -
Apr 2025
Early-life wheeze trajectories are associated with distinct asthma transcriptomes later in life
J Allergy Clin ImmunolKieran J Phelan, Krishna M Roskin, Jeffrey W Burkle, Wan-Chi Chang, Lisa J Martin , Jocelyn M Biagini, Latha Satish, David B Haslam, Daniel Spagna, Seth Jenkins, Elsie Parmar, Leonard B Bacharier, Tebeb Gebretsadik, Michelle Gill, Diane R Gold, Daniel J Jackson, Christine C Johnson, Susan V Lynch, Kathryn E McCauley, Chris G McKennan, Rachel Miller, Carole Ober, Dennis R Ownby, Patrick H Ryan, Nathan Schoettler, Sweta Singh, Cynthia M Visness, Matthew C Altman, James E Gern, Gurjit K Khurana Hershey, Environmental Influences on Child Health Outcomes–Children’s Respiratory and Environmental Workgroup -
Apr 2025
TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation
EMBO RepThomas E Schultz, Carmen D Mathmann, Leslie C Domínguez Cadena, Timothy W Muusse, Hyoyoung Kim, James W Wells, Glen C Ulett, Jessica A Hamerman, Andrew J Brooks, Bostjan Kobe, Matthew J Sweet, Katryn J Stacey, Antje Blumenthal -
Apr 2025
Rheumatoid arthritis - the role of T cells in this complex systemic autoimmune disease.
Curr Opin ImmunolSavvides CS, James EA, Buckner JH -
Apr 2025
T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblasts
J Invest DermatolHannah A DeBerg, Mitch L Fahning, Suraj R Varkhande, James D Schlenker, William P Schmitt, Aayush Gupta, Archana Singh, Iris K Gratz, Jeffrey S Carlin, Daniel J Campbell, Peter A Morawski