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Jun 2024
A haplotype-resolved view of human gene regulation.
bioRxivVollger MR, Swanson EG, Neph SJ, Ranchalis J, Munson KM, Ho C-H, Sedeno-Cortes AE, Fondrie WE, Bohaczuk ST, Mao Y, Parmalee NL, Mallory BJ, Harvey WT, Kwon Y, Garcia GH, Hoekzema K, Meyer JG, Cicek M, Eichler EE, Noble WS, Witten DM, Bennett JT, Ray JP, Stergachis AB. -
Jun 2024
Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas.
Nat CommunLinsley PS, Nakayama M, Balmas E, Chen J, Barahmand-Pour-Whitman F, Bansal S, Bottorff T, Serti E, Speake C, Pugliese A, Cerosaletti K -
May 2024
The insulin secretory granule is a hotspot for autoantigen formation in type 1 diabetes.
DiabetologiaGroegler J, Callebaut A, James EA, Delong T -
May 2024
Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention.
NEJM EvidDu Toit G, Huffaker MF, Radulovic S, Feeney M, Fisher HR, Byron M, Dunaway L, Calatroni A, Johnson M, Foong RX, Marques-Mejias A, Bartha I, Basting M, Brough HA, Baloh C, Laidlaw TM, Bahnson HT, Roberts G, Plaut M, Wheatley LM, Lack G, Immune Tolerance Network LEAP-Trio Trial Team -
May 2024
Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures.
Arthritis RheumatolChiche L, Jourde-Chiche N, Whalen E, Presnell S, Gersuk V, Dang K, Anguiano E, Quinn C, Burtey S, Berland Y, Kaplanski G, Harle JR, Pascual V, Chaussabel D -
May 2024
Comparison of biomarkers for systemic juvenile idiopathic arthritis.
Pediatr ResShenoi S, Ou JN, Ni C, Macaubas C, Gersuk VH, Wallace CA, Mellins ED, Stevens AM -
May 2024
Vitamin D Deficiency Is Associated With Increased Risk of Non-alcoholic Steatohepatitis in Adults With Non-alcoholic Fatty Liver Disease: Possible Role for MAPK and NF-κB?
Am J GastroenterolNelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-Stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV -
May 2024
Blood-Borne RNA Correlates with Disease Activity and IFN-Stimulated Gene Expression in Systemic Lupus Erythematosus.
J ImmunolDoedens JR, Jones WD, Hill K, Mason MJ, Gersuk VH, Mease PJ, Dall'Era M, Aranow C, Martin RW, Cohen SB, Fleischmann RM, Kivitz AJ, Burge DJ, Chaussabel D, Elkon KB, Posada JA -
May 2024
Presymptomatic diagnosis of postoperative infection and sepsis using gene expression signatures.
Intensive Care MedLukaszewski RA, Jones HE, Gersuk VH, Russell P, Simpson A, Brealey D, Walker J, Thomas M, Whitehouse T, Ostermann M, Koch A, Zacharowski K, Kruhoffer M, Chaussabel D, Singer M -
May 2024
Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations.
Nat CommunSzczesny B, Boorgula MP, Chavan S, Campbell M, Johnson RK, Kammers K, Thompson EE, Cox MS, Shankar G, Cox C, Morin A, Lorizio W, Daya M, Kelada SNP, Beaty TH, Doumatey AP, Cruz AA, Watson H, Naureckas ET, Giles BL, Arinola GA, Sogaolu O, Falade AG, Hansel NN, Yang IV, Olopade CO, Rotimi CN, Landis RC, Figueiredo CA, Altman MC, Kenny E, Ruczinski I, Liu AH, Ober C, Taub MA, Barnes KC, Mathias RA -
May 2024
Integrating Omics into Functional Biomarkers of Type 1 Diabetes.
Cold Spring Harb Perspect MedLong SA, Linsley PS -
May 2024
SKI Regulates Medullary Thymic Epithelial Cell Differentiation to Control Peripheral T Cell Responses in Mice.
J ImmunolChiu H, Weinstein KN, Spath S, Hu A, Varela S, Obata-Ninomiya K, Ziegler SF -
May 2024
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis.
Sci Transl MedBai Z, Bartelo N, Aslam M, Murphy EA, Hale CR, Blachere NE, Parveen S, Spolaore E, DiCarlo E, Gravallese EM, Smith MH, Accelerating Medicines Partnership RA/SLE Network, Frank MO, Jiang CS, Zhang H, Pyrgaki C, Lewis MJ, Sikandar S, Pitzalis C, Lesnak JB, Mazhar K, Price TJ, Malfait AM, Miller RE, Zhang F, Goodman S, Darnell RB, Wang F, Orange DE -
May 2024
Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers.
ImmunityVerma S, Dufort MJ, Olsen TM, Kimmel S, Labuda JC, Scharffenberger S, McGuire AT, Harrison OJ -
May 2024
A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy.
J Allergy Clin ImmunolZoratti E, Wood R, Pomés A, da Silva Antunes R, Altman MC, Benson B, Wheatley LM, Cho K, Calatroni A, Little FF, Pongracic J, Makhija M, Khurana Hershey GK, Sherenian MG, Rivera-Spoljaric K, Stokes JR, Gill MA, Gruchalla RS, Chambliss J, Liu AH, Kattan M, Busse PJ, Bacharier LB, Sheehan W, Kim H, Glesner J, Gergen PJ, Togias A, Baucom JL, Visness CM, Sette A, Busse WW, Jackson DJ, Inner-City Asthma and Childhood Asthma in Urban Settings Consortia