Biorepository: Type 1 Diabetes

People with T1D making a difference

What is BRI’s Diabetes Biorepository?

The Diabetes Biorepository is a confidential list of people with type 1 diabetes (T1D) who donate samples and provide health information for scientific research. This library of samples and information helps our scientists study how and why T1D starts and make progress toward prevention and better treatments.

Participate in Diabetes Research

We invite individuals with T1D to participate in this research to help us improve our understanding of diabetes and immune-mediated diseases.

We are also looking for family members of all ages who do not have type Type 1 diabetes or another immune-mediated or autoimmune disease, to join our Healthy Volunteer Registry.

Participating in research typically involves a 45-60 -minute visit to BRI in downtown Seattle. Our team will collect a blood sample and ask questions about your personal and family medical history. All samples and information are kept confidential. Learn more: Biorepository FAQ

Learn more about type 1 diabetes.

Are you living with or at risk of developing T1D?

Consider donating to our biorepository or participating in our T1D research.

Donate to our Biorepository Learn about T1D clinical trials at BRI

Clinical Director, Center for Interventional Immunology

Sandra Lord, MD

Director, Clinical Research Center

By the Numbers

3,806+

Unique T1D Volunteers

98,873+

Samples, some longitudinal

Labs Studying Type 1 Diabetes

Buckner Lab Banner

Buckner Lab

The Buckner Lab is focused on identifying the underlying mechanisms by which regulation of the adaptive immune response fails or is overcome in the setting of human autoimmunity.

Campbell Lab Banner

Campbell Lab

The Campbell laboratory is interested in understanding the basis for T cell activation, function and tolerance.

Cerosaletti Research Project Banner - Autoreactive T cells in type 1 diabetes

Cerosaletti Lab

Dr. Cerosaletti’s research is focused on the role of the adaptive immune system in the development and progression of immune mediated diseases and the response to treatment.

Greenbaum Lab Banner

Greenbaum Lab

Our group focuses on prediction and prevention of type 1 diabetes (T1D) as well as discovery and validation of biomarkers of disease progression and response to therapy.

James Lab Banner

James Lab

The James lab is working to develop an increasingly in depth knowledge of autoreactive T cell responses by examining the characteristics of the epitope specific cells involved in autoimmune diseases through robust multi-parameter assays and also at the single cell level.

Kwok Research Project Banner - DNA-barcoded HLA class II tetramers

Kwok Lab

The Kwok lab uses tetramers and other antigen specific T cell assays to examine autoreactive T cells in autoimmune diseases in order to provide insights into disease mechanisms and identify strategies for disease intervention.

Linsley Lab Banner

Linsley Lab

Our goal is to develop and use cutting edge systems biology approaches to elucidate molecular signatures of complex immune diseases, understand the mechanisms of disease, and identify the right therapy for the right patient.

Long Lab Banner

Long Lab

The Long Lab focuses on understanding mechanisms of tolerance, why they are lost in autoimmunity, and how tolerance can be augmented with therapy.

Speake Research Project Banner - TrialNet Pathway to Prevention

Speake Lab

The Speake group is interested in advancing clinical research – especially in type 1 diabetes, but also in the context of other immune-mediated diseases.

Collaborate with us

We want to advance the science to predict, prevent, reverse and ultimately cure T1D and seek out opportunities to collaborate. We have the technology, participants, expertise, samples and desire. Learn about all of the ways we collaborate, we look forward to hearing from you.

Learn more about opportunities for collaboration

News

Blog Main Image - T1D Diabetes Medical Technology

Seattle - Nov 14, 2024

Type 1 Diabetes Community Celebrates Research Milestone During National Diabetes Month

First row, left to right: Jessica Hamerman, PhD; Adam Lacy-Hulbert, PhD; Peter Morawski, PhD; Jane Buckner, MD. Second row, left to right: Eddie James, PhD; John Ray, PhD; Estelle Bettelli, PhD; James Lord, MD, PhD

Seattle - Oct 9, 2024

Benaroya Research Institute Awarded More Than $14 Million Across 11 Grants To Help Predict, Prevent, Reverse and Cure Immune System Diseases

Photo of Zane Burris

The Boeing Classic Is More Than a Golf Tournament, It’s a Catalyst for Cures

Blog Stories

Blog Main Image - T1D Diabetes Medical Technology

Autoantibody Reversion: A Mystery That Could Help Prevent T1D

At first, Cate Speake, PhD, and her team weren’t sure that a mysterious phenomenon called autoantibody reversion was actually happening. But no matter how they sliced the data, they saw the same pattern. Learn how autoantibody reversion could unlock new clues to preventing type 1 diabetes.

Blog CII T1D Family Day EDITORIAL

September 24, 2024

Second Annual BRI T1D Family Day

June 1, 2024, marked the second annual Benaroya Research Institute T1D Family Day.

Blog CII T1D Alexis and Harper EDITORIAL

September 24, 2024

Working Toward Cures

Did you know that if risk screening results show you are in the early stages of T1D, you may be eligible to participate in a type 1 diabetes prevention study?

Immuno-what? Hear the latest from BRI

Keep up to date on our latest research, new clinical trials and exciting publications.

Subscribe to our newsletter