Buckner Lab

Autoimmunity

Introduction

The Buckner Lab is focused on identifying the underlying mechanisms by which regulation of the adaptive immune response fails or is overcome in the setting of human autoimmunity. Our multipronged approach integrates the study of genes associated with disease risk, the study of lymphocyte populations implicated in the pathogenesis of autoimmune disease and the analysis of carefully curated biological samples from well-characterized subjects with type 1 diabetes, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus and relapsing polychondritis.

The goal in all of our studies is to understand how pathways known to regulate the immune response are altered in the setting of disease, and further when and how these mechanisms of failed tolerance contribute to the development and progression of human disease.

Jane Buckner
BRI President

Jane Buckner, MD

President, BRI; Member; Principal Investigator, Buckner Lab; Center for Translational Immunology
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Lab Members

Aleah DeSchmidt

Aleah DeSchmidt

Research Technician, Buckner Lab; Center for Translational Immunology
Victor Lui

Victor Lui, PhD

PostDoctoral Researcher, Buckner Lab; Center for Translational Immunology
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Ethan McClain

Ethan McClain

Research Technician, Buckner Lab; Center for Translational Immunology
Mishra Arpit

Arpit Mishra, PhD

Staff Scientist, Buckner Lab; Center for Translational Immunology
Emma Mortensen

Emma Mortensen

Research Technician, Buckner Lab; Center for Translational Immunology
Sylvia Posso

Sylvia Posso

Translational Research Project Manager, Buckner Lab; Center for Translational Immunology
Cliff Rims

Cliff Rims

Research Technician, Buckner Lab; Center for Translational Immunology
Song Jing

Jing Song, PhD

Staff Scientist, Buckner Lab; Center for Translational Immunology
Megan Tatum

Megan Tatum, BS

Research Technician, Buckner Lab; Center for Translational Immunology
Ritika Tewari

Ritika Tewari, PhD

Staff Scientist, Buckner Lab; Center for Translational Immunology
Soo Jung Yang

Soo Jung Yang, PhD

Research Assistant Member; Principal Investigator, Yang Lab; Center for Translational Immunology