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Paradoxically increased FOXP3+ T cells in IBD do not preferentially express the isoform of FOXP3 lacking exon 2.
Dig Dis SciLord JD, Valliant-Saunders K, Hahn H, Thirlby RC, Ziegler SF -
Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection.
J Allergy Clin ImmunolLee HC, Headley MB, Loo YM, Berlin A, Gale M Jr, Debley JS, Lukacs NW, Ziegler SF -
Identification of novel HLA class II target epitopes for generation of donor-specific T regulatory cells.
Clin ImmunolStone B, Rieck M, Rawlings CA, Kas A, Shendure J, Jones H, Buckner JH -
Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand.
J Allergy Clin ImmunolHan J, Dakhama A, Jia Y, Wang M, Zeng W, Takeda K, Shiraishi Y, Okamoto M, Ziegler SF, Gelfand EW -
Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.
Arthritis RheumMikuls TR, Thiele GM, Deane KD, Payne JB, O'Dell JR, Yu F, Sayles H, Weisman MH, Gregersen PK, Buckner JH, Keating RM, Derber LA, Robinson WH, Holers VM, Norris JM -
Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide.
J Biol ChemHull RL, Peters MJ, Perigo SP, Chan CK, Wight TN, Kinsella MG -
The role of hyaluronan and the extracellular matrix in islet inflammation and immune regulation.
Curr Diab RepBollyky PL, Bogdani M, Bollyky JB, Hull RL, Wight TN -
Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types.
J Histochem CytochemHull RL, Johnson PY, Braun KR, Day AJ, Wight TN -
A functional framework for interpretation of genetic associations in T1D.
Curr Opin ImmunolNepom GT, Buckner JH -
Thymic stromal lymphopoietin and allergic disease.
J Allergy Clin ImmunolZiegler SF -
HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term.
J VirolVingert B, Benati D, Lambotte O, de Truchis P, Slama L, Jeannin P, Galperin M, Perez-Patrigeon S, Boufassa F, Kwok WW, Lemaître F, Delfraissy JF, Thèze J, Chakrabarti LA -
T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2.
ImmunityKoch MA, Thomas KR, Perdue NR, Smigiel KS, Srivastava S, Campbell DJ -
Systematic localization of common disease-associated variation in regulatory DNA.
ScienceMaurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, Wang H, Reynolds AP, Sandstrom R, Qu H, Brody J, Shafer A, Neri F, Lee K, Kutyavin T, Stehling-Sun S, Johnson AK, Canfield TK, Giste E, Diegel M, Bates D, Hansen RS, Neph S, Sabo PJ, Heimfeld S, Raubitschek A, Ziegler S, Cotsapas C, Sotoodehnia N, Glass I, Sunyaev SR, Kaul R, Stamatoyannopoulos JA, Ziegler SF -
Type-1 immunity drives early lethality in scurfy mice.
Eur J ImmunolSuscovich TJ, Perdue NR, Campbell DJ -
Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function.
DiabetesLong SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network.
