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Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection.
The Journal of Allergy and Clinical ImmunologyLee HC, Headley MB, Loo YM, Berlin A, Gale M Jr, Debley JS, Lukacs NW, Ziegler SF -
Identification of novel HLA class II target epitopes for generation of donor-specific T regulatory cells.
Clinical ImmunologyStone B, Rieck M, Rawlings CA, Kas A, Shendure J, Jones H, Buckner JH -
Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand.
The Journal of Allergy and Clinical ImmunologyHan J, Dakhama A, Jia Y, Wang M, Zeng W, Takeda K, Shiraishi Y, Okamoto M, Ziegler SF, Gelfand EW -
Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.
Arthritis and RheumatismMikuls TR, Thiele GM, Deane KD, Payne JB, O'Dell JR, Yu F, Sayles H, Weisman MH, Gregersen PK, Buckner JH, Keating RM, Derber LA, Robinson WH, Holers VM, Norris JM -
Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide.
The Journal of Biological ChemistryHull RL, Peters MJ, Perigo SP, Chan CK, Wight TN, Kinsella MG -
The role of hyaluronan and the extracellular matrix in islet inflammation and immune regulation.
Current Diabetes ReportsBollyky PL, Bogdani M, Bollyky JB, Hull RL, Wight TN -
Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types.
The Journal of Histochemistry and CytochemistryHull RL, Johnson PY, Braun KR, Day AJ, Wight TN -
A functional framework for interpretation of genetic associations in T1D.
Current Opinion in ImmunologyNepom GT, Buckner JH -
Thymic stromal lymphopoietin and allergic disease.
The Journal of Allergy and Clinical ImmunologyZiegler SF -
HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term.
Journal of VirologyVingert B, Benati D, Lambotte O, de Truchis P, Slama L, Jeannin P, Galperin M, Perez-Patrigeon S, Boufassa F, Kwok WW, Lemaître F, Delfraissy JF, Thèze J, Chakrabarti LA -
T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2.
ImmunityKoch MA, Thomas KR, Perdue NR, Smigiel KS, Srivastava S, Campbell DJ -
Systematic localization of common disease-associated variation in regulatory DNA.
ScienceMaurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, Wang H, Reynolds AP, Sandstrom R, Qu H, Brody J, Shafer A, Neri F, Lee K, Kutyavin T, Stehling-Sun S, Johnson AK, Canfield TK, Giste E, Diegel M, Bates D, Hansen RS, Neph S, Sabo PJ, Heimfeld S, Raubitschek A, Ziegler S, Cotsapas C, Sotoodehnia N, Glass I, Sunyaev SR, Kaul R, Stamatoyannopoulos JA, Ziegler SF -
Type-1 immunity drives early lethality in scurfy mice.
European Journal of ImmunologySuscovich TJ, Perdue NR, Campbell DJ -
Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function.
DiabetesLong SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network. -
Compartmentalized control of skin immunity by resident commensals.
ScienceNaik S, Bouladoux N, Wilhelm C, Molloy MJ, Salcedo R, Kastenmuller W, Deming C, Quinones M, Koo L, Conlan S, Spencer S, Hall JA, Dzutsev A, Kong H, Campbell DJ, Trinchieri G, Segre JA, Belkaid Y