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DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9.
Mol ImmunolChow IT, James EA, Tan V, Moustakas AK, Papadopoulos GK, Kwok WW -
Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy.
J Allergy Clin ImmunolWambre E, DeLong JH, James EA, LaFond RE, Robinson D, Kwok WW -
Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance.
J Allergy Clin ImmunolPalomares O, Rückert B, Jartti T, Kücüksezer UC, Puhakka T, Gomez E, Fahrner HB, Speiser A, Jung A, Kwok WW, Kalogjera L, Akdis M, Akdis CA -
Ultra-sensitive detection of rare T cell clones.
J Immunol MethodsRobins H, Desmarais C, Matthis J, Livingston R, Andriesen J, Reijonen H, Carlson C, Nepom GT, Yee C , Cerosaletti K -
Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence.
J Exp MedSchulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan BE, Streeck H, Aneja J, Reyor LL, Allen TM, Lohse AW, McGovern B, Chung RT, Kwok WW, Kim AY, Lauer GM -
B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K.
Proc Natl Acad Sci U S ANi M, MacFarlane AW 4th, Toft M, Lowell CA, Campbell KS, Hamerman JA -
Sleep, glucose, and daytime functioning in youth with type 1 diabetes
SleepPerfect MM, Patel PG, Scott RE, Wheeler MD, Patel C, Griffin K, Sorensen ST, Goodwin JL, Quan SF -
Miniaturized assays of angiogenesis in vitro.
Methods Mol BiolReed MJ, Vernon RB -
Reversal of diabetes in mice with a bioengineered islet implant incorporating a type I collagen hydrogel and sustained release of vascular endothelial growth factor.
Cell TransplantVernon RB, Preisinger A, Gooden MD, D'Amico LA, Yue BB, Bollyky PL, Kuhr CS, Hefty TR, Nepom GT, Gebe JA -
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells.
Eur J ImmunolIto H, Hamerman JA -
Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant.
J ImmunolHabib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi AK, Luning Prak ET, Meyer-Bahlburg A, Sanda S, Greenbaum CJ, Rawlings DJ, Buckner JH -
Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience.
Rev Diabet StudEhlers MR, Nepom GT -
Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22.
Rev Diabet StudCerosaletti K, Buckner JH -
Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice.
J ImmunolNishiura H, Kido M, Aoki N, Iwamoto S, Maruoka R, Ikeda A, Chiba T, Ziegler SF, Watanabe N -
Interleukin-7, but not thymic stromal lymphopoietin, plays a key role in the T cell response to influenza A virus.
PLoS OnePlumb AW, Patton DT, Seo JH, Loveday EK, Jean F, Ziegler SF, Abraham N