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A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.
J Clin InvestDai X, James RG, Habib T, Singh S, Jackson S, Khim S, Moon RT, Liggitt D, Wolf-Yadlin A, Buckner JH, Rawlings DJ -
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines.
ImmunityObermoser G, Presnell S, Domico K, Xu H, Wang Y, Anguiano E, Thompson-Snipes L, Ranganathan R, Zeitner B, Bjork A, Anderson D, Speake C, Ruchaud E, Skinner J, Alsina L, Sharma M, Dutartre H, Cepika A, Israelsson E, Nguyen P, Nguyen QA, Harrod AC, Zurawski SM, Pascual V, Ueno H, Nepom GT, Quinn C, Blankenship D, Palucka K, Banchereau J, Chaussabel D -
The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Nat ImmunolBell BD, Kitajima M, Larson RP, Stoklasek TA, Dang K, Sakamoto K, Wagner KU, Kaplan DH, Reizis B, Hennighausen L, Ziegler SF -
Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.
Mech DevWilson CL, Gough PJ, Chang CA, Chan CK, Frey JM, Liu Y, Braun KR, Chin MT, Wight TN, Raines EW -
Regulatory T cells: recommendations to simplify the nomenclature.
Nat ImmunolAbbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF -
Hepatitis C virus promotes T-helper (Th)17 responses through thymic stromal lymphopoietin production by infected hepatocytes.
HepatologyLee HC, Sung SS, Krueger PD, Jo YA, Rosen HR, Ziegler SF, Hahn YS -
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.
J ImmunolSun X, Wiedeman A, Agrawal N, Teal TH, Tanaka L, Hudkins KL, Alpers CE, Bolland S, Buechler MB, Hamerman JA, Ledbetter JA, Liggitt D, Elkon KB -
miRNAs regulate expression and function of extracellular matrix molecules.
Matrix BiolRutnam ZJ, Wight TN, Yang BB -
β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation.
Eur J ImmunolYee NK, Hamerman JA -
CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring.
ImmunologyYang J, James EA, Sanda S, Greenbaum CJ, Kwok WW -
A case of fatal idiopathic enteritis and multiple opportunistic infections associated with dendritic cell deficiencies.
J Gastrointestin Liver DisLord JD, Chen J, Kozarek RA -
Reply: To PMID 22981788.
J Allergy Clin ImmunolZiegler SF -
Cutting edge: Type I IFN drives emergency myelopoiesis and peripheral myeloid expansion during chronic TLR7 signaling.
J ImmunolBuechler MB, Teal TH, Elkon KB, Hamerman JA -
Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages.
J ImmunolHan H, Headley MB, Xu W, Comeau MR, Zhou B, Ziegler SF -
In active relapsing-remitting multiple sclerosis, effector T cell resistance to adaptive T(regs) involves IL-6-mediated signaling.
Sci Transl MedSchneider A, Long SA, Cerosaletti K, Ni CT, Samuels P, Kita M, Buckner JH
