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Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives.
DiabetesStandifer NE, Ouyang Q, Panagiotopoulos C, Verchere CB, Tan R, Greenbaum CJ, Pihoker C, Nepom GT -
A haplotype-based analysis of the PTPN22 locus in type 1 diabetes.
DiabetesOnengut-Gumuscu S, Buckner JH, Concannon P -
Matricellular hevin regulates decorin production and collagen assembly.
The Journal of Biological ChemistrySullivan MM, Barker TH, Funk SE, Karchin A, Seo NS, Höök M, Sanders J, Starcher B, Wight TN, Puolakkainen P, Sage EH -
Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study.
DiabetesSeyfert-Margolis V, Gisler TD, Asare AL, Wang RS, Dosch HM, Brooks-Worrell B, Eisenbarth GS, Palmer JP, Greenbaum CJ, Gitelman SE, Nepom GT, Bluestone JA, Herold KC -
V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis.
Laboratory Investigation; a Journal of Technical Methods and PathologyMiquel-Serra L, Serra M, Hernández D, Domenzain C, Docampo MJ, Rabanal RM, de Torres I, Wight TN, Fabra A, Bassols A -
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor.
Journal of ImmunologyLopes JE, Torgerson TR, Schubert LA, Anover SD, Ocheltree EL, Ochs HD, Ziegler SF -
The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells.
Biochimica et Biophysica ActaKaji T, Yamamoto C, Oh-i M, Fujiwara Y, Yamazaki Y, Morita T, Plaas AH, Wight TN -
DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.
PNAS USADurinovic-Belló I, Rosinger S, Olson JA, Congia M, Ahmad RC, Rickert M, Hampl J, Kalbacher H, Drijfhout JW, Mellins ED, Al Dahouk S, Kamradt T, Maeurer MJ, Nhan C, Roep BO, Boehm BO, Polychronakos C, Nepom GT, Karges W, McDevitt HO, Sønderstrup G -
Versican degradation and vascular disease.
Trends in Cardiovascular MedicineKenagy RD, Plaas AH, Wight TN -
HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease.
The Journal of Clinical InvestigationTollefsen S, Arentz-Hansen H, Fleckenstein B, Molberg O, Ráki M, Kwok WW, Jung G, Lundin KE, Sollid LM -
FOXP3 controls regulatory T cell function through cooperation with NFAT.
CellWu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A -
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.
The Journal of Experimental MedicineLiu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA -
A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia
Nat GenetHorvath A, Boikos S, Giatzakis C, Robinson-White A, Groussin L, Griffin KJ, Stein E, Levine E, Delimpasi G, Hsiao HP, Keil M, Heyerdahl S, Matyakhina L, Libé R, Fratticci A, Kirschner LS, Cramer K, Gaillard RC, Bertagna X, Carney JA, Bertherat J, Bossis I, Stratakis CA -
Multiplex mapping of CD4 T cell epitopes using class II tetramers.
Clinical ImmunologyYang J, James EA, Huston L, Danke NA, Liu AW, Kwok WW -
Thymic stromal lymphopoietin in normal and pathogenic T cell development and function.
Nature ImmunologyZiegler SF, Liu YJ