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Dec 1998
Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.
J ImmunolEttinger RA, Liu AW, Nepom GT, Kwok WW -
Dec 1998
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.
Nat GenetPuel A, Ziegler SF, Buckley RH, Leonard WJ -
Oct 1998
Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR.
J ImmunolDoherty DG, Penzotti JE, Koelle DM, Kwok WW, Lybrand TP, Masewicz S, Nepom GT -
Sep 1998
Recognition of herpes simplex virus type 2 tegument proteins by CD4 T cells infiltrating human genital herpes lesions.
J VirolKoelle DM, Frank JM, Johnson ML, Kwok WW -
Aug 1998
Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells.
J Clin InvestHershberg RM, Cho DH, Youakim A, Bradley MB, Lee JS, Framson PE, Nepom GT -
Aug 1998
Molecular basis for HLA-DQ associations with IDDM.
DiabetesNepom GT, Kwok WW -
Jul 1998
Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes.
J ImmunolBourdette DN, Chou YK, Whitham RH, Buckner JH, Kwon HJ, Nepom GT, Buenafe A, Cooper SA, Allegretta M, Hashim GA, Offner H, Vandenbark AA -
May 1998
Novel glycosylation of HLA-DRalpha disrupts antigen presentation without altering endosomal localization.
J ImmunolGuerra CB, Busch R, Doebele RC, Liu W, Sawada T, Kwok WW, Chang MD, Mellins ED -
Apr 1998
HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments.
Ann Rheum DisO'Dell JR, Nepom BS, Haire C, Gersuk VH, Gaur L, Moore GF, Drymalski W, Palmer W, Eckhoff PJ, Klassen LW, Wees S, Thiele G, Nepom GT -
Mar 1998
Promiscuous T-cell recognition of a rubella capsid protein epitope restricted by DRB1*0403 and DRB1*0901 molecules sharing an HLA DR supertype.
Hum ImmunolOu D, Mitchell LA, Décarie D, Tingle AJ, Nepom GT -
Mar 1998
A peptide binding motif for HLA-DQA1*0102/DQB1*0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus.
J ImmunolEttinger RA, Kwok WW -
Feb 1998
Modulation of peptide-dependent allospecific epitopes on HLA-DR4 molecules by HLA-DM.
Hum ImmunolDrover S, Kovats S, Masewicz S, Blum JS, Nepom GT -
Jan 1998
HLA-DR class II associations with rubella vaccine-induced joint manifestations.
J Infect DisMitchell LA, Tingle AJ, MacWilliam L, Horne C, Keown P, Gaur LK, Nepom GT -
Jan 1998
Major histocompatibility complex-directed susceptibility to rheumatoid arthritis.
Adv ImmunolNepom GT -
Aug 1997
High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.
J AutoimmunBach JM, Otto H, Nepom GT, Jung G, Cohen H, Timsit J, Boitard C, van Endert PM