-
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis.
RMD OpenTurcinov S, Sharma RK, De Vries C, Cîrciumaru A, Gerstner C, Mathsson-Alm L, Raposo B, Dubnovitsky A, Rönnblom L, Kwok WW, Chemin K, Malmström V, Hensvold A -
B cell adapter for PI 3-kinase (BCAP) coordinates antigen internalization and trafficking through the B cell receptor.
Sci AdvLagos J, Holder U, Sagadiev S, Montiel-Armendariz A, Li LZ, Pasare C, Hou B, Hamerman JA, Acharya M -
Synovial regulatory T cells expressing ST2 deteriorate joint inflammation through the suppression of immunoregulatory eosinophils.
J AutoimmunHattori K, Tanaka S, Hashiba D, Tamura J, Etori K, Kageyama T, Ito T, Meguro K, Iwata A, Suto A, Suzuki K, Nakamura J, Ohtori S, Ziegler SF, Nakajima H -
Are Glycans Really Non-templated? Deploying AI Deciphers how the Underlying Protein Helps Shape their Glycans
GlycobiologyKellman BP, Sandoval D, Zaytseva OO, Brock K, Baboo S, Nachmanson D, Irvine EB, Armingol E, Mih N, Zhang Y, Jeffris M, Bartels P, Nguyen T, Tam A, Gasman S, Ilan S, Shamie I, Diedrich JK, Wang X, van Woudenbergh E, Altman M, Aylward A, Bao B, Castro A, Sorrentino J, Chiang A, Campbell M, Bartsch Y, Aguilar-Calvo P, Sigurdson C, Alter G, Lauc G, Yates III JR, Marks D, Lisacek F, Mariethoz J, Shaul S, Alteri M, Bojar D, Lewis NE -
An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy.
Cell RepJamison BL, Lawrance M, Wang CJ, DeBerg HA, Ziegler LJ, Sansom DM, Gavin MA, Walker LSK, Campbell DJ -
Antigen-specific T-cell frequency and phenotype mirrors disease activity in DRB1*04:04+ rheumatoid arthritis patients.
Clinical and Experimental ImmunologyRims C, Uchtenhagen H, Brooks K, Ng B, Posso SE, Carlin J, Kwok WW, Buckner JH, James EA -
Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy.
Journal of AutoimmunityTewari R, Yang SJ, McClain ED, Hu A, Mortensen E, DeSchmidt A, Chen J, Kancharla A, Singh AK, James EA, Burman BE, Siddique A, Rawlings DJ, Patel C, Cerosaletti K, Buckner JH -
Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks
Nat GenetChing-Huang Ho, Maxwell A Dippel, Meghan S McQuade, LeAnn P Nguyen, Arpit Mishra, Stephan Pribitzer, Samantha Hardy, Harshpreet Chandok, Florence M Chardon, Troy A McDiarmid, Hannah A DeBerg, Jane H Buckner , Jay Shendure, Carl G de Boer, Michael H Guo, Ryan Tewhey, John P Ray -
Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.
CellsNagy N, Czepiel KS, Kaber G, Stefanovski D, Hargil A, Pennetzdorfer N, Targ R, Reghupaty SC, Wight TN, Vernon RB, Hull-Meichle RL, Marshall P, Medina CO, Martinez H, Kalinowski A, Paladini RD, Garantziotis S, Knowles JW, Bollyky PL -
B cell αv integrin regulates germinal center derived lung-resident IgA B cell responses following influenza virus infection.
Sci AdvAndrea Montiel-Armendariz, Kelsey Roe, Jonathan Lagos, Laura Veronica Martinez-Castro, Matthew J Dufort, Oliver J Harrison, Adam Lacy-Hulbert, Mridu Acharya -
Thymic stromal lymphopoietin signaling in B cells from progenitors to plasma cells.
Journal of Leukocyte BiologyDomeier PP, Ziegler SF -
Application of Hemolymph Smear Histology Diagnosis to Detect Disseminated Neoplasia in Basket Cockles (Clinocardium nuttallii).
J Shellfish Res.Vandepas LE, Crim RN, Gilbertson E, Yonemitsu MA, Unsell E, Metzger MJ, Lacy-Hulbert A, Goetz FW -
The path ahead for understanding Toll-like receptors-driven systemic autoimmunity.
Current Opinion in ImmunologyHamerman JA, Barton GM -
Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers.
DiabetologiaZhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A -
Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation.
ElifePahl MC, Sharma P, Thomas RM, Thompson Z, Mount Z, Pippin JA, Morawski PA, Sun P, Su C, Campbell D, Grant SFA, Wells AD
