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Presymptomatic diagnosis of postoperative infection and sepsis using gene expression signatures.
Intensive Care MedicineLukaszewski RA, Jones HE, Gersuk VH, Russell P, Simpson A, Brealey D, Walker J, Thomas M, Whitehouse T, Ostermann M, Koch A, Zacharowski K, Kruhoffer M, Chaussabel D, Singer M -
Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations.
Nature CommunicationsSzczesny B, Boorgula MP, Chavan S, Campbell M, Johnson RK, Kammers K, Thompson EE, Cox MS, Shankar G, Cox C, Morin A, Lorizio W, Daya M, Kelada SNP, Beaty TH, Doumatey AP, Cruz AA, Watson H, Naureckas ET, Giles BL, Arinola GA, Sogaolu O, Falade AG, Hansel NN, Yang IV, Olopade CO, Rotimi CN, Landis RC, Figueiredo CA, Altman MC, Kenny E, Ruczinski I, Liu AH, Ober C, Taub MA, Barnes KC, Mathias RA -
Integrating Omics into Functional Biomarkers of Type 1 Diabetes.
Cold Spring Harbor Perspectives in MedicineLong SA, Linsley PS -
SKI Regulates Medullary Thymic Epithelial Cell Differentiation to Control Peripheral T Cell Responses in Mice.
Journal of ImmunologyChiu H, Weinstein KN, Spath S, Hu A, Varela S, Obata-Ninomiya K, Ziegler SF -
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis.
Science Translational MedicineBai Z, Bartelo N, Aslam M, Murphy EA, Hale CR, Blachere NE, Parveen S, Spolaore E, DiCarlo E, Gravallese EM, Smith MH, Accelerating Medicines Partnership RA/SLE Network, Frank MO, Jiang CS, Zhang H, Pyrgaki C, Lewis MJ, Sikandar S, Pitzalis C, Lesnak JB, Mazhar K, Price TJ, Malfait AM, Miller RE, Zhang F, Goodman S, Darnell RB, Wang F, Orange DE -
Protein Structure, a Genetic Encoding for Glycosylation
bioRxivKellman BP, Sandoval D, Zaytseva OO, Brock K, Sabyasachi B, Nachmanson D, Irvine EB, Armingol E, Mih N, Zhang Y, Jeffris M, Bartels P, Nguyen T, Tam A, Gasman S, Ilan S, Shamie I, Diedrich JK, Wang X, van Woudenbergh E, Altman Meghan, Aylward A, Bao B, Castro A, Sorrentino J, Chiang A, Campbell M, Bartsch Y, Aguilar-Calvo P, Sigurdson C, Alter G, Lauc G, Yates III JR, Marks D, Lisacek F, Lewis NE -
Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers.
ImmunityVerma S, Dufort MJ, Olsen TM, Kimmel S, Labuda JC, Scharffenberger S, McGuire AT, Harrison OJ -
A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy.
The Journal of Allergy and Clinical ImmunologyZoratti E, Wood R, Pomés A, da Silva Antunes R, Altman MC, Benson B, Wheatley LM, Cho K, Calatroni A, Little FF, Pongracic J, Makhija M, Khurana Hershey GK, Sherenian MG, Rivera-Spoljaric K, Stokes JR, Gill MA, Gruchalla RS, Chambliss J, Liu AH, Kattan M, Busse PJ, Bacharier LB, Sheehan W, Kim H, Glesner J, Gergen PJ, Togias A, Baucom JL, Visness CM, Sette A, Busse WW, Jackson DJ, Inner-City Asthma and Childhood Asthma in Urban Settings Consortia -
A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes.
Science Translational MedicineBender C, Wiedeman AE, Hu A, Ylescupidez A, Sietsema WK, Herold KC, Griffin KJ, Gitelman SE, Long SA, T-Rex Study Group†, T-Rex Clinical Study Group -
Beyond Stages: Predicting Individual Time Dependent Risk for Type 1 Diabetes.
The Journal of Clinical Endocrinology and MetabolismPribitzer S, O'Rourke C, Ylescupidez A, Smithmyer M, Bender C, Speake C, Lord S, Greenbaum CJ -
Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.
The Journal of Clinical InvestigationGygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK, IMPACC Network, Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L -
Impact on in-depth immunophenotyping of delay to peripheral blood processing.
Clinical and Experimental ImmunologyHigdon LE, Scheiding S, Kus AM, Lim N, Long SA, Anderson MS, Wiedeman AE -
Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency.
The Journal of Experimental MedicineJohnson MB, Ogishi M, Domingo-Vila C, de Franco E, Wakeling MN, Imane Z, Resnick B, Williams E, Galão RP, Caswell R, Russ-Silsby J, Seeleuthner Y, Rinchai D, Fagniez I, Benson B, Dufort MJ, Speake C, Smithmyer ME, Hudson M, Dobbs R, EXE-T1D consortium, Quandt Z, Hattersley AT, Zhang P, Boisson-Dupuis S, Anderson MS, Casanova JL, Tree TI, Oram RA -
Abatacept increases T cell exhaustion in early RA individuals who carry HLA risk alleles.
Frontiers in ImmunologyLong SA, Muir VS, Jones BE, Wall VZ, Ylescupidez A, Hocking AM, Pribitzer S, Thorpe J, Fuchs B, Wiedeman AE, Tatum M, Lambert K, Uchtenhagen H, Speake C, Ng B, Heubeck AT, Torgerson TR, Savage AK, Maldonado MA, Ray N, Khaychuk V, Liu J, Linsley PS, Buckner JH -
T-cell receptor sequencing in interrogating antigen-specific T-cell responses to foreign and self-antigens.
The Journal of Allergy and Clinical ImmunologyJohansson AM, Kwok WW
