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Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.
DiabetesShapiro MR, Wasserfall CH, McGrail SM, Posgai AL, Bacher R, Muir A, Haller MJ, Schatz DA, Wesley JD, von Herrath M, Hagopian WA, Speake C, Atkinson MA, Brusko TM -
Increased islet antigen-specific regulatory and effector CD4+ T cells in healthy individuals with the type 1 diabetes-protective haplotype.
Sci ImmunolWen X, Yang J, James EA, Chow IT , Reijonen H , Kwok WW -
Integrative network modeling reveals mechanisms underlying T cell exhaustion.
Sci RepBolouri H, Young M, Beilke J, Johnson R, Fox B, Huang L, Santini CC, Hill CM, Vries AVV, Shannon PT, Dervan A, Sivakumar P, Trotter M, Bassett D, Ratushny A -
Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC.
Diabetes CareMishra R, Åkerlund M, Cousminer DL, Ahlqvist E, Bradfield JP, Chesi A, Hodge KM, Guy VC, Brillon DJ, Pratley RE, Rickels MR, Vella A, Ovalle F, Harris RI, Melander O, Varvel S, Hakonarson H, Froguel P, Lonsdale JT, Mauricio D, Schloot NC, Khunti K, Greenbaum CJ, Yderstræde KB, Tuomi T, Voight BF, Schwartz S, Boehm BO, Groop L, Leslie RD, Grant SFA -
IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE.
JCI InsightLi D, Matta B, Song S, Nelson V, Diggins K, Simpfendorfer KR, Gregersen PK, Linsley PS, Barnes BJ -
Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases.
Front ImmunolReeves SR, Barrow KA, Rich LM, White MP, Shubin NJ, Chan CK, Kang I, Ziegler SF, Piliponsky AM, Wight TN, Debley JS -
Inflammatory Cytokines Induce Sustained CTLA-4 Cell Surface Expression on Human MAIT Cells.
ImmunohorizonsBerkson JD, Slichter CK, DeBerg HA, Delaney MA, Woodward-Davis AS, Maurice NJ, Lwo Y, Ko A, Hsu J, Chiu YW, Linsley PS, Dixon D, Prlic M -
Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy.
Nat CommunSheih A, Voillet V, Hanafi LA, DeBerg HA, Yajima M, Hawkins R, Gersuk V, Riddell SR, Maloney DG, Wohlfahrt ME, Pande D, Enstrom MR, Kiem HP, Adair JE, Gottardo R, Linsley PS, Turtle CJ -
Evolving concepts in how viruses impact asthma: A Work Group Report of the Microbes in Allergy Committee of the American Academy of Allergy, Asthma & Immunology
J Allergy Clin ImmunolAltman MC, Beigelman A, Ciaccio C, Gern JE, Heymann PW, Jackson DJ, Kennedy JL, Kloepfer K, Lemanske RF Jr, McWilliams LM, Muehling L, Nance C, Peebles RS Jr -
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.
J Clin InvestWiedeman AE, Muir VS, Rosasco MG, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James EA, Linsley PS, Long SA -
Stability and dynamics of the human gut microbiome and its association with systemic immune traits
bioRxivByrd AL, Liu M, Fujimura KE, Lyalina S, Nagarkar DR, Charbit B, Bergstedt J, Patin E, Harrison OJ, Quintana-Murci L, Duffy D, Albert ML, Milieu Intérieur Consortium. -
A 71-year-old man with recurrent pulmonary mycobacterial avium complex infections and lymphopenia
Allergy Asthma ProcAl-Shaikhly T, Buckner FS, Altman MC -
Perioperative anaphylaxis in children: Etiology, time sequence, and patterns of clinical reactivity.
Pediatr Allergy ImmunolKhaleva E, Franz A, Garvey LH, Jay N, Ylescupidez A, Bahnson HT, Du Toit G -
Restricted myeloperoxidase epitopes drive the adaptive immune response in MPO-ANCA vasculitis.
J AutoimmunFree ME, Stember KG, Hess JJ, McInnis EA, Lardinois O, Hogan SL, Hu Y, Mendoza C, Le AK, Guseman AJ, Pilkinton MA, Bortone DS, Cowens K, Sidney J, Karosiene E, Peters B, James EA, Kwok WW, Vincent BG, Mallal SA, Jennette JC, Ciavatta DJ, Falk RJ -
In-vivo assessment of T cell kinetics in individuals at risk for type 1 diabetes.
Clin Exp ImmunolHao W, Bahnson HT, Speake C, Cerosaletti K, Greenbaum CJ
