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Insulin is necessary but not sufficient: changing the therapeutic paradigm in type 1 diabetes.
F1000ResLord S, Greenbaum CJ -
Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells.
JCI InsightNeiman D, Gillis D, Piyanzin S, Cohen D, Fridlich O, Moss J, Zick A, Oron T, Sundberg F, Forsander G, Skog O, Korsgren O, Levy-Khademi F, Arbel D, Hashavia S, Shapiro AMJ, Speake C, Greenbaum CJ, Hosford J, Posgai AL, Atkinson MA, Glaser B, Schatz DA, Shemer R, Dor Y -
Apoptotic cells induce CD103 expression and immunoregulatory function in myeloid dendritic cell precursors through integrin αv and TGF-β activation.
PLoS OneZhang A, Paidassi H, Lacy-Hulbert A, Savill J -
Immunity to commensal skin fungi promotes psoriasiform skin inflammation.
Proc Natl Acad Sci U S AHurabielle C, Link VM, Bouladoux N, Han SJ, Merrill ED, Lightfoot YL, Seto N, Bleck CKE, Smelkinson M, Harrison OJ, Linehan JL, Tamoutounour S, Lionakis MS, Kaplan MJ, Nakajima S, Belkaid Y -
Poised for tissue repair.
ScienceHarrison OJ -
Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis.
JCI InsightCarmona-Rivera C, Carlucci PM, Goel RR, James EA, Brooks SR, Rims C, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ -
A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin.
Sci RepKlicznik MM, Benedetti A, Gail LM, Varkhande SR, Holly R, Laimer M, Stoecklinger A, Sir A, Reitsamer R, Neuper T, Horejs-Hoeck J, Rosenblum MD, Campbell DJ, Murauer EM, Gratz IK -
Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2.
J Allergy Clin ImmunolJackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC -
Combined chemotherapy and radiotherapy improves survival in 1897 testicular Lymphoma patients from a contemporary cohort.
Urol OncolCaumont F, Porter C, DeBerg H, Burns J, Frankel J, Flores JP -
The synthesis and secretion of versican isoform V3 by mammalian cells: A role for N-linked glycosylation.
Matrix BiolHarten IA, Kaber G, Agarwal KJ, Kang I, Ibarrientos SR, Workman G, Chan CK, Nivison MP, Nagy N, Braun KR, Kinsella MG, Merrilees MJ, Wight TN -
Thymic stromal lymphopoietin protects in a model of airway damage and inflammation via regulation of caspase-1 activity and apoptosis inhibition.
Mucosal ImmunolShubin NJ, Clauson M, Niino K, Kasprzak V, Tsuha A, Guga E, Bhise G, Acharya M, Snyder JM, Debley JS, Ziegler SF, Piliponsky AM -
Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation.
Mucosal ImmunolKabata H, Flamar AL, Mahlakõiv T, Moriyama S, Rodewald HR, Ziegler SF, Artis D -
Critical Role of TSLP Receptor on CD4 T Cells for Exacerbation of Skin Inflammation.
J ImmunolKitajima M, Kubo M, Ziegler SF, Suzuki H -
An accumulation of two populations of dendritic cells in skin-draining lymph nodes in response to the expression of thymic stromal lymphopoietin in the skin.
Cell ImmunolOmori-Miyake M, Watarai H, Sato K, Ziegler SF, Yagi J -
Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children.
DiabetesZhao LP, Papadopoulos GK, Kwok WW, Moustakas AK, Bondinas GP, Larsson HE, Ludvigsson J, Marcus C, Samuelsson U, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A