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Apr 2019
Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.
J ImmunolStathopoulos P, Chastre A, Waters P, Irani S, Fichtner ML, Benotti ES, Guthridge JM, Seifert J, Nowak RJ, Buckner JH, Holers VM, James JA, Hafler DA, O'Connor KC -
Apr 2019
How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci ImmunolWang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S -
Apr 2019
Coordinated Induction of Antimicrobial Response Factors in Systemic Lupus Erythematosus.
Front ImmunolAyyappan P, Harms RZ, Buckner JH, Sarvetnick NE -
Apr 2019
Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis.
DiabetologiaPerdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold KC, Immune Tolerance Network. -
Apr 2019
Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes.
Genes ImmunLinsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ -
Apr 2019
Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.
Arthritis RheumatolRims C, Uchtenhagen H, Kaplan MJ, Carmona-Rivera C, Carlucci P, Mikecz K, Markovics A, Carlin J, Buckner JH, James EA -
Apr 2019
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
EBioMedicineJames JA, Chen H, Young KA, Bemis EA, Seifert J, Bourn RL, Deane KD, Demoruelle MK, Feser M, O'Dell JR, Weisman MH, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Harley JB, Robinson W, Hafler DA, O'Connor KC, Buckner JH, Guthridge JM, Norris JM, Holers VM -
Apr 2019
Epithelial cell-derived cytokines: more than just signaling the alarm.
J Clin InvestRoan F, Obata-Ninomiya K, Ziegler SF -
Mar 2019
Treg gene signatures predict and measure type 1 diabetes trajectory.
JCI InsightPesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK -
Mar 2019
Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.
Curr Diab RepJohnson MB, Cerosaletti K, Flanagan SE, Buckner JH -
Mar 2019
Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation.
Proc Natl Acad Sci U S ASchrock DC, Leddon SA, Hughson A, Miller J, Lacy-Hulbert A, Fowell DJ -
Mar 2019
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
J ImmunolGlatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E -
Mar 2019
Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions".
J Allergy Clin ImmunolDavidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M -
Feb 2019
Cell type-specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes.
JCI InsightDufort MJ, Greenbaum CJ, Speake C, Linsley PS -
Feb 2019
B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes.
JCI InsightLinsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ