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Approaches to Establishing Tolerance in Immune Mediated Diseases.
Front ImmunolHuffaker MF, Sanda S, Chandran S, Chung SA, St Clair EW, Nepom GT, Smilek DE -
HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA.
Arthritis Res TherRigby W, Buckner JH, Louis Bridges S Jr, Nys M, Gao S, Polinsky M, Ray N, Bykerk V -
Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19.
PLoS PathogHeide J, Schulte S, Kohsar M, Brehm TT, Herrmann M, Karsten H, Marget M, Peine S, Johansson AM, Sette A, Lütgehetmann M, Kwok WW, Sidney J, Schulze Zur Wiesch J -
Evaluating associations of joint swelling, joint stiffness and joint pain with physical activity in first-degree relatives of patients with rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA), a prospective cohort study.
BMJ OpenHughes-Austin JM, Ix JH, Ward SR, Weisman MH, ODell JR, Mikuls TR, Buckner JH, Gregersen PK, Keating RM, Demoruelle MK, Deane KD, Holers VM, Norris JM -
PGD2 and CRTH2 counteract Type 2 cytokine-elicited intestinal epithelial responses during helminth infection.
J Exp MedOyesola OO, Shanahan MT, Kanke M, Mooney BM, Webb LM, Smita S, Matheson MK, Campioli P, Pham D, Früh SP, McGinty JW, Churchill MJ, Cahoon JL, Sundaravaradan P, Flitter BA, Mouli K, Nadjsombati MS, Kamynina E, Peng SA, Cubitt RL, Gronert K, Lord JD, Rauch I, von Moltke J, Sethupathy P, Tait Wojno ED -
Optimal human pathogenic TH2 cell effector function requires local epithelial cytokine signaling.
J Allergy Clin ImmunolCalise J, Garabatos N, Bajzik V, Farrington M, Robinson D, Jeong D, Londei M, Wambre E -
The parasite cytokine mimic Hp-TGM potently replicates the regulatory effects of TGF-β on murine CD4+ T cells.
Immunol Cell BiolWhite MPJ, Smyth DJ, Cook L, Ziegler SF, Levings MK, Maizels RM -
Induction of stable human FOXP3+ Tregs by a parasite-derived TGF-β mimic.
Immunol Cell BiolCook L, Reid KT, Häkkinen E, de Bie B, Tanaka S, Smyth DJ, White MP, Wong MQ, Huang Q, Gillies JK, Ziegler SF, Maizels RM, Levings MK -
Overview of oral tolerance induction for prevention of food allergy-Where are we now?
AllergyKrawiec M, Fisher HR, Du Toit G, Bahnson HT, Lack G -
Evolution of epitope-specific IgE and IgG4 antibodies in children enrolled in the LEAP trial.
J Allergy Clin ImmunolSuarez-Farinas M, Suprun M, Bahnson HT, Raghunathan R, Getts R, duToit G, Lack G, Sampson HA -
Thymic stromal lymphopoietin, skin barrier dysfunction, and the atopic march.
Ann Allergy Asthma ImmunolZiegler SF -
Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer.
Front OncolHirani P, Gauthier V, Allen CE, Wight TN, Pearce OMT -
The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway.
Mol Cell BiolArnett A, Moo KG, Flynn KJ, Sundberg TB, Johannessen L, Shamji AF, Gray NS, Decker T, Zheng Y, Gersuk VH, Rahman ZS, Levy DE, Marié IJ, Linsley PS, Xavier RJ, Khor B -
Signals governing monocyte differentiation during inflammation.
Curr Opin ImmunolOrozco SL, Canny SP, Hamerman JA -
Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome.
ElifeMarié IJ, Brambilla L, Azzouz D, Chen Z, Baracho GV, Arnett A, Li HS, Liu W, Cimmino L, Chattopadhyay P, Silverman G, Watowich SS, Khor B, Levy DE