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HLA-DQ beta sequence polymorphism and genetic susceptibility to IDDM.
DiabetesErlich HA, Bugawan TL, Scharf S, Nepom GT, Tait B, Griffith RL -
Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition.
J Exp MedKwok WW, Mickelson E, Masewicz S, Milner EC, Hansen J, Nepom GT -
Mutagenesis and expression of putative class II susceptibility genes: a "reverse immunogenetics" approach to analysis of HLA and disease.
AutoimmunityNepom GT -
A specific HLA-DP beta allele is associated with pauciarticular juvenile rheumatoid arthritis but not adult rheumatoid arthritis.
Proc Natl Acad Sci U S ABegovich AB, Bugawan TL, Nepom BS, Klitz W, Nepom GT, Erlich HA -
A genetically controlled pairing anomaly between HLA-DQ alpha and HLA-DQ beta chains.
J ImmunolKwok WW, Thurtle P, Nepom GT -
Determinants of genetic susceptibility in HLA-associated autoimmune disease.
Clin Immunol ImmunopatholNepom GT -
The effects of variations in human immune-response genes.
N Engl J MedNepom GT -
The benzodiazepine receptor ligands RO 5-4864 and RO 15-1788 do not block the inhibition of PAF-induced platelet aggregation seen with the hetrazepine WEB2086
Biochem Biophys Res CommunGriffin K, Hong T, Levy JV -
Mutational analysis of the HLA-DQ3.2 insulin-dependent diabetes mellitus susceptibility gene.
Proc Natl Acad Sci U S AKwok WW, Lotshaw C, Milner EC, Knitter-Jack N, Nepom GT -
Inherited diseases in North American Mennonites: focus on Old Colony (Chortitza) Mennonites.
Am J Med GenetJaworski MA, Severini A, Mansour G, Hennig K, Slater JD, Jeske R, Schlaut J, Yoon JW, Maclaren NK, Nepom GT -
HLA genes associated with rheumatoid arthritis. Identification of susceptibility alleles using specific oligonucleotide probes.
Arthritis RheumNepom GT, Byers P, Seyfried C, Healey LA, Wilske KR, Stage D, Nepom BS -
HLA DQ beta 3.2 identifies subtypes of DR4+ haplotypes permissive for IDDM.
Genet EpidemiolRobinson DM, Holbeck S, Palmer JP, Nepom GT -
HLA class II typing using oligonucleotide probes.
Genet EpidemiolRobinson DM, Holbeck S, Seyfried C, Byers P, Palmer JP, Nepom GT -
Structural variation among major histocompatibility complex class-II genes which predispose to autoimmunity.
Immunol ResNepom GT -
Sequence analysis of HLA class II domains: characterization of the DQw3 family of DQB genes.
ImmunogeneticsHiraiwa A, Seyfried CE, Nepom GT, Milner EC
