-
Use of T cell receptor/HLA-DRB1*04 molecular modeling to predict site-specific interactions for the DR shared epitope associated with rheumatoid arthritis.
Arthritis and RheumatismPenzotti JE, Nepom GT, Lybrand TP -
Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing.
The Journal of Clinical InvestigationHershberg RM, Framson PE, Cho DH, Lee LY, Kovats S, Beitz J, Blum JS, Nepom GT -
alphaT244M mutation affects the redox, kinetic, and in vitro folding properties of Paracoccus denitrificans electron transfer flavoprotein
BiochemistryGriffin KJ, Dwyer TM, Manning MC, Meyer JD, Carpenter JF, Frerman FE -
Recognition of contiguous allele-specific peptide elements in the rubella virus E1 envelope protein.
VaccineNepom GT, Domeier ME, Ou D, Kovats S, Mitchell LA, Tingle AJ -
MHC-DRB allelic sequences incorporate distinct intragenic trans-specific segments.
Tissue AntigensGaur LK, Nepom GT, Snyder KE, Anderson J, Pandarpurkar M, Yadock W, Heise ER -
Preferential presentation of herpes simplex virus T-cell antigen by HLA DQA1*0501/DQB1*0201 in comparison to HLA DQA1*0201/DQB1*0201.
Human ImmunologyKoelle DM, Johnson ML, Ekstrom AN, Byers P, Kwok WW -
Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.
The Journal of Clinical InvestigationWicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ -
CD11b+CD28-CD4+ human T cells: activation requirements and association with HLA-DR alleles.
Journal of ImmunologyChapman A, Stewart SJ, Nepom GT, Green WF, Crowe D, Thomas JW, Miller GG -
Modulation of HLA-DQ binding properties by differences in class II dimer stability and pH-dependent peptide interactions.
Journal of ImmunologyBuckner JH, Kwok WW, Nepom BS, Nepom GT -
Characterization of the HLA-restrictive elements of a rubella virus-specific cytotoxic T cell clone: influence of HLA-DR4 beta chain residue 74 polymorphism on antigenic peptide-T cell interaction.
International ImmunologyOu D, Mitchell LA, Domeier ME, Tsang AO, Décarie D, Tingle AJ, Nepom GT, Lacroix M, Zrein M -
Critical contribution of beta chain residue 57 in peptide binding ability of both HLA-DR and -DQ molecules.
PNAS USANepom BS, Nepom GT, Coleman M, Kwok WW -
Ancestral major histocompatibility complex DRB genes beget conserved patterns of localized polymorphisms.
PNAS USAGaur LK, Nepom GT -
Recognition of altered self major histocompatibility complex molecules modulated by specific peptide interactions.
European Journal of ImmunologyNepom GT, Ou D, Lybrand TP, DeWeese C, Domeier ME, Buckner JH, Mitchell LA, Tingle AJ -
A structural model for TCR recognition of the HLA class II shared epitope sequence implicated in susceptibility to rheumatoid arthritis.
Journal of AutoimmunityPenzotti JE, Doherty D, Lybrand TP, Nepom GT -
Allele-specific motifs characterize HLA-DQ interactions with a diabetes-associated peptide derived from glutamic acid decarboxylase.
Journal of ImmunologyKwok WW, Domeier ML, Raymond FC, Byers P, Nepom GT
