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Accumulation of(125)iodine labeled interleukin-2 in the pancreas of NOD mice.
Journal of AutoimmunityRolandsson O, Stigbrand T, Riklundåhlström K, Eary J, Greenbaum CJ -
The amount of scurfin protein determines peripheral T cell number and responsiveness.
Journal of ImmunologyKhattri R, Kasprowicz D, Cox T, Mortrud M, Appleby MW, Brunkow ME, Ziegler SF, Ramsdell F -
Generation of high quantities of viral and tumor-specific human CD4+ and CD8+ T-cell clones using peptide pulsed mature dendritic cells.
Journal of Immunological MethodsFonteneau JF, Larsson M, Somersan S, Sanders C, Münz C, Kwok WW, Bhardwaj N, Jotereau F -
Rapid epitope identification from complex class-II-restricted T-cell antigens.
Trends in ImmunologyKwok WW, Gebe JA, Liu A, Agar S, Ptacek N, Hammer J, Koelle DM, Nepom GT -
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation.
The Journal of Biological ChemistrySchubert LA, Jeffery E, Zhang Y, Ramsdell F, Ziegler SF -
T cell selection and differential activation on structurally related HLA-DR4 ligands.
Journal of ImmunologyGebe JA, Novak EJ, Kwok WW, Farr AG, Nepom GT, Buckner JH -
Islet cell antibodies and glutamic acid decarboxylase antibodies, but not the clinical phenotype, help to identify type 1(1/2) diabetes in patients presenting with type 2 diabetes.
Metabolism: Clinical and ExperimentalJuneja R, Hirsch IB, Naik RG, Brooks-Worrell BM, Greenbaum CJ, Palmer JP -
Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset.
International ImmunologyNovak EJ, Masewicz SA, Liu AW, Lernmark A, Kwok WW, Nepom GT -
Tetramer-guided epitope mapping: rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens.
Journal of ImmunologyNovak EJ, Liu AW, Gebe JA, Falk BA, Nepom GT, Koelle DM, Kwok WW -
The role of the DR4 shared epitope in selection and commitment of autoreactive T cells in rheumatoid arthritis.
Rheumatic Diseases Clinics of North AmericaNepom GT -
Intermolecular antigen spreading occurs during the preclinical period of human type 1 diabetes.
Journal of ImmunologyBrooks-Worrell B, Gersuk VH, Greenbaum CJ, Palmer JP -
CD8 CTL from genital herpes simplex lesions: recognition of viral tegument and immediate early proteins and lysis of infected cutaneous cells.
Journal of ImmunologyKoelle DM, Chen HB, Gavin MA, Wald A, Kwok WW, Corey L -
Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).
PNAS USANepom GT, Lippolis JD, White FM, Masewicz S, Marto JA, Herman A, Luckey CJ, Falk B, Shabanowitz J, Hunt DF, Engelhard VH, Nepom BS -
Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria.
DiabetesGreenbaum CJ, Cuthbertson D, Krischer JP, Disease Prevention Trial of Type I Diabetes Study Group. -
Low-dose streptozotocin induces sustained hyperglycemia in Macaca nemestrina.
AutoimmunityGaur LK, Nepom GT, Lernmark A