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Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.
Nat GenetPuel A, Ziegler SF, Buckley RH, Leonard WJ -
Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR.
J ImmunolDoherty DG, Penzotti JE, Koelle DM, Kwok WW, Lybrand TP, Masewicz S, Nepom GT -
Recognition of herpes simplex virus type 2 tegument proteins by CD4 T cells infiltrating human genital herpes lesions.
J VirolKoelle DM, Frank JM, Johnson ML, Kwok WW -
Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells.
J Clin InvestHershberg RM, Cho DH, Youakim A, Bradley MB, Lee JS, Framson PE, Nepom GT -
Molecular basis for HLA-DQ associations with IDDM.
DiabetesNepom GT, Kwok WW -
Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes.
J ImmunolBourdette DN, Chou YK, Whitham RH, Buckner JH, Kwon HJ, Nepom GT, Buenafe A, Cooper SA, Allegretta M, Hashim GA, Offner H, Vandenbark AA -
31P-NMR spectroscopy of human and Paracoccus denitrificans electron transfer flavoproteins, and 13C- and 15N-NMR spectroscopy of human electron transfer flavoprotein in the oxidised and reduced states
Eur J BiochemGriffin KJ, Degala GD, Eisenreich W, Müller F, Bacher A, Frerman FE -
Novel glycosylation of HLA-DRalpha disrupts antigen presentation without altering endosomal localization.
J ImmunolGuerra CB, Busch R, Doebele RC, Liu W, Sawada T, Kwok WW, Chang MD, Mellins ED -
HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments.
Ann Rheum DisO'Dell JR, Nepom BS, Haire C, Gersuk VH, Gaur L, Moore GF, Drymalski W, Palmer W, Eckhoff PJ, Klassen LW, Wees S, Thiele G, Nepom GT -
Promiscuous T-cell recognition of a rubella capsid protein epitope restricted by DRB1*0403 and DRB1*0901 molecules sharing an HLA DR supertype.
Hum ImmunolOu D, Mitchell LA, Décarie D, Tingle AJ, Nepom GT -
A peptide binding motif for HLA-DQA1*0102/DQB1*0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus.
J ImmunolEttinger RA, Kwok WW -
Modulation of peptide-dependent allospecific epitopes on HLA-DR4 molecules by HLA-DM.
Hum ImmunolDrover S, Kovats S, Masewicz S, Blum JS, Nepom GT -
HLA-DR class II associations with rubella vaccine-induced joint manifestations.
J Infect DisMitchell LA, Tingle AJ, MacWilliam L, Horne C, Keown P, Gaur LK, Nepom GT -
Major histocompatibility complex-directed susceptibility to rheumatoid arthritis.
Adv ImmunolNepom GT -
High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.
J AutoimmunBach JM, Otto H, Nepom GT, Jung G, Cohen H, Timsit J, Boitard C, van Endert PM
