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Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65.
AutoimmunityMasewicz SA, Meldrum N, Gersuk V, Gaur L, Hagopian W, Moriarity L, Nepom GT -
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
Nature GeneticsBrunkow ME, Jeffery EW, Hjerrild KA, Paeper B, Clark LB, Yasayko SA, Wilkinson JE, Galas D, Ziegler SF, Ramsdell F -
School-age children born to diabetic mothers and to mothers with gestational diabetes exhibit a high rate of inattention and fine and gross motor impairment.
Journal of Pediatric Endocrinology & MetabolismOrnoy A, Ratzon N, Greenbaum C, Wolf A, Dulitzky M -
A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin.
The Journal of Clinical InvestigationAlleva DG, Crowe PD, Jin L, Kwok WW, Ling N, Gottschalk M, Conlon PJ, Gottlieb PA, Putnam AL, Gaur A -
Distinct T cell interactions with HLA class II tetramers characterize a spectrum of TCR affinities in the human antigen-specific T cell response.
Journal of ImmunologyReichstetter S, Ettinger RA, Liu AW, Gebe JA, Nepom GT, Kwok WW -
Tegument-specific, virus-reactive CD4 T cells localize to the cornea in herpes simplex virus interstitial keratitis in humans.
Journal of VirologyKoelle DM, Reymond SN, Chen H, Kwok WW, McClurkan C, Gyaltsong T, Petersdorf EW, Rotkis W, Talley AR, Harrison DA -
GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.
DiabetesReijonen H, Daniels TL, Lernmark A, Nepom GT -
Beta 57-Asp plays an essential role in the unique SDS stability of HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC allele associated with protection from insulin-dependent diabetes mellitus.
Journal of ImmunologyEttinger RA, Liu AW, Nepom GT, Kwok WW -
Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.
The Journal of Experimental MedicinePark LS, Martin U, Garka K, Gliniak B, Di Santo JP, Müller W, Largaespada DA, Copeland NG, Jenkins NA, Farr AG, Ziegler SF, Morrissey PJ, Paxton R, Sims JE -
Increased frequency of HLA class II alleles DRB1*0301 and DQB1*0201 in Lambert-Eaton myasthenic syndrome without associated cancer.
Human ImmunologyParsons KT, Kwok WW, Gaur LK, Nepom GT -
Gene therapy in the treatment of autoimmune diseases.
The Journal of Clinical InvestigationTsokos GC, Nepom GT -
Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin.
Nature ImmunologyPandey A, Ozaki K, Baumann H, Levin SD, Puel A, Farr AG, Ziegler SF, Leonard WJ, Lodish HF -
HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: direct detection of immunodominant antigen-responsive cells.
Journal of ImmunologyKwok WW, Liu AW, Novak EJ, Gebe JA, Ettinger RA, Nepom GT, Reymond SN, Koelle DM -
Autoreactivity against matrilin-1 in a patient with relapsing polychondritis.
Arthritis and RheumatismBuckner JH, Wu JJ, Reife RA, Terato K, Eyre DR -
Epstein-Barr virus entry utilizing HLA-DP or HLA-DQ as a coreceptor.
Journal of VirologyHaan KM, Kwok WW, Longnecker R, Speck P
