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A peptide binding motif for HLA-DQA1*0102/DQB1*0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus.
J ImmunolEttinger RA, Kwok WW -
Modulation of peptide-dependent allospecific epitopes on HLA-DR4 molecules by HLA-DM.
Hum ImmunolDrover S, Kovats S, Masewicz S, Blum JS, Nepom GT -
HLA-DR class II associations with rubella vaccine-induced joint manifestations.
J Infect DisMitchell LA, Tingle AJ, MacWilliam L, Horne C, Keown P, Gaur LK, Nepom GT -
Major histocompatibility complex-directed susceptibility to rheumatoid arthritis.
Adv ImmunolNepom GT -
High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.
J AutoimmunBach JM, Otto H, Nepom GT, Jung G, Cohen H, Timsit J, Boitard C, van Endert PM -
Immunodominance of a low-affinity major histocompatibility complex-binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire.
J Clin InvestMuraro PA, Vergelli M, Kalbus M, Banks DE, Nagle JW, Tranquill LR, Nepom GT, Biddison WE, McFarland HF, Martin R -
Use of T cell receptor/HLA-DRB1*04 molecular modeling to predict site-specific interactions for the DR shared epitope associated with rheumatoid arthritis.
Arthritis RheumPenzotti JE, Nepom GT, Lybrand TP -
Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing.
J Clin InvestHershberg RM, Framson PE, Cho DH, Lee LY, Kovats S, Beitz J, Blum JS, Nepom GT -
alphaT244M mutation affects the redox, kinetic, and in vitro folding properties of Paracoccus denitrificans electron transfer flavoprotein
BiochemistryGriffin KJ, Dwyer TM, Manning MC, Meyer JD, Carpenter JF, Frerman FE -
Recognition of contiguous allele-specific peptide elements in the rubella virus E1 envelope protein.
VaccineNepom GT, Domeier ME, Ou D, Kovats S, Mitchell LA, Tingle AJ -
MHC-DRB allelic sequences incorporate distinct intragenic trans-specific segments.
Tissue AntigensGaur LK, Nepom GT, Snyder KE, Anderson J, Pandarpurkar M, Yadock W, Heise ER -
Preferential presentation of herpes simplex virus T-cell antigen by HLA DQA1*0501/DQB1*0201 in comparison to HLA DQA1*0201/DQB1*0201.
Hum ImmunolKoelle DM, Johnson ML, Ekstrom AN, Byers P, Kwok WW -
Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.
J Clin InvestWicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ -
CD11b+CD28-CD4+ human T cells: activation requirements and association with HLA-DR alleles.
J ImmunolChapman A, Stewart SJ, Nepom GT, Green WF, Crowe D, Thomas JW, Miller GG -
Modulation of HLA-DQ binding properties by differences in class II dimer stability and pH-dependent peptide interactions.
J ImmunolBuckner JH, Kwok WW, Nepom BS, Nepom GT
