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Detection of CD4+ autoreactive T cells in T1D using HLA class II tetramers.
Ann N Y Acad SciReijonen H, Kwok WW, Nepom GT -
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells.
J Clin InvestWalker MR, Kasprowicz DJ, Gersuk VH, Benard A, Van Landeghen M, Buckner JH, Ziegler SF -
Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2.
J VirolIyasere C, Tilton JC, Johnson AJ, Younes S, Yassine-Diab B, Sekaly RP, Kwok WW, Migueles SA, Laborico AC, Shupert WL, Hallahan CW, Davey RT Jr, Dybul M, Vogel S, Metcalf J, Connors M -
HLA class II-restricted CD4+ T cell responses directed against influenza viral antigens postinfluenza vaccination.
J ImmunolDanke NA, Kwok WW -
CD69-null mice protected from arthritis induced with anti-type II collagen antibodies.
Int ImmunolMurata K, Inami M, Hasegawa A, Kubo S, Kimura M, Yamashita M, Hosokawa H, Nagao T, Suzuki K, Hashimoto K, Shinkai H, Koseki H, Taniguchi M, Ziegler SF, Nakayama T -
Scurfin (FoxP3) controls T-dependent immune responses in vivo through regulation of CD4+ T cell effector function.
J ImmunolKasprowicz DJ, Smallwood PS, Tyznik AJ, Ziegler SF -
P53(110-124)-specific human CD4+ T-helper cells enhance in vitro generation and antitumor function of tumor-reactive CD8+ T cells.
Cancer ResChikamatsu K, Albers A, Stanson J, Kwok WW, Appella E, Whiteside TL, DeLeo AB -
Low-avidity recognition by CD4+ T cells directed to self-antigens.
Eur J ImmunolGebe JA, Falk BA, Rock KA, Kochik SA, Heninger AK, Reijonen H, Kwok WW, Nepom GT -
Conversations with GAD.
J AutoimmunNepom GT -
Guidelines for intervention trials in subjects with newly diagnosed type 1 diabetes.
DiabetesGreenbaum CJ, Harrison LC, Immunology of Diabetes Society. -
Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes.
MethodsReijonen H, Kwok WW -
Binding of outer surface protein A and human lymphocyte function-associated antigen 1 peptides to HLA-DR molecules associated with antibiotic treatment-resistant Lyme arthritis.
Arthritis RheumSteere AC, Falk B, Drouin EE, Baxter-Lowe LA, Hammer J, Nepom GT -
Differential antigen sensitivity and costimulatory requirements in human Th1 and Th2 antigen-specific CD4+ cells with similar TCR avidity.
J ImmunolHolzer U, Kwok WW, Nepom GT, Buckner JH -
HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells.
Clin ImmunolMaus MV, Riley JL, Kwok WW, Nepom GT, June CH -
MHC multimers: expanding the clinical toolkit.
Clin ImmunolNepom GT