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Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.
PLoS OneChow IT, Yang J, Gates TJ, James EA, Mai DT, Greenbaum CJ, Kwok WW -
Thymic stromal lymphopoietin and cancer.
J ImmunolLo Kuan E, Ziegler SF -
T cell-associated α4β7 but not α4β1 integrin is required for the induction and perpetuation of chronic colitis.
Mucosal ImmunolKurmaeva E, Lord JD, Zhang S, Bao JR, Kevil CG, Grisham MB, Ostanin DV -
Molecular signatures differentiate immune states in type 1 diabetic families.
DiabetesChen YG, Cabrera SM, Jia S, Kaldunski ML, Kramer J, Cheong S, Geoffrey R, Roethle MF, Woodliff JE, Greenbaum CJ, Wang X, Hessner MJ -
A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4
Nat ImmunolAlsina L, Israelsson E, Altman MC, Dang KK, Ghandil P, Israel L, von Bernuth H, Baldwin N, Qin H, Jin Z, Banchereau R, Anguiano E, Ionan A, Abel L, Puel A, Picard C, Pascual V, Casanova JL, Chaussabel D -
Copy number loss of the interferon gene cluster in melanomas is linked to reduced T cell infiltrate and poor patient prognosis.
PLoS OneLinsley PS, Speake C, Whalen E, Chaussabel D -
Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.
Proc Natl Acad Sci U S AYang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW -
Biogeography and individuality shape function in the human skin metagenome
NatureOh J, Byrd AL, Deming C, Conlan S, NISC Comparative Sequencing Program, Kong HH, Segre JA -
The role of basophils and proallergic cytokines, TSLP and IL-33, in cutaneously sensitized food allergy.
Int ImmunolMuto T, Fukuoka A, Kabashima K, Ziegler SF, Nakanishi K, Matsushita K, Yoshimoto T -
Circulating Type-1 Anti-Tumor CD4(+) T Cells are Preferentially Pro-Apoptotic in Cancer Patients.
Front OncolWesa AK, Mandic M, Taylor JL, Moschos S, Kirkwood JM, Kwok WW, Finke JH, Storkus WJ -
IFNαR signaling in effector but not regulatory T cells is required for immune dysregulation during type I IFN-dependent inflammatory disease.
J ImmunolSrivastava S, Koch LK, Campbell DJ -
PathoScope 2.0: a complete computational framework for strain identification in environmental or clinical sequencing samples
MicrobiomeHong C, Manimaran S, Shen Y, Perez-Rogers JF, Byrd AL, Castro-Nallar E, Crandall KA, Johnson WE -
Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
Proc Natl Acad Sci U S AWatanabe Y, Onodera A, Kanai U, Ichikawa T, Obata-Ninomiya K, Wada T, Kiuchi M, Iwamura C, Tumes DJ, Shinoda K, Yagi R, Motohashi S, Hirahara K, Nakayama T -
Elimination of Pasteurella pneumotropica from a mouse barrier facility by using a modified enrofloxacin treatment regimen
J Am Assoc Lab Anim SciTowne JW, Wagner AM, Griffin KJ, Buntzman AS, Frelinger JA, Besselsen DG -
Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components.
J Allergy Clin ImmunolReeves SR, Kolstad T, Lien TY, Elliott M, Ziegler SF, Wight TN, Debley JS