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Direct Analysis of Insulin-Specific T Cells Provides New Insights.
DiabetesJames EA -
Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.
Am J Physiol Lung Cell Mol PhysiolChang MY, Kang I, Gale M Jr, Manicone AM, Kinsella MG, Braun KR, Wigmosta T, Parks WC, Altemeier WA, Wight TN, Frevert CW -
Assessment of β Cell Mass and Function by AIRmax and Intravenous Glucose in High-Risk Subjects for Type 1 Diabetes.
J Clin Endocrinol MetabHao W, Woodwyk A, Beam C, Bahnson HT, Palmer JP, Greenbaum CJ -
Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes: A Randomized Clinical Trial.
JAMAWriting Committee for the Type 1 Diabetes TrialNet Oral Insulin Study Group., Krischer JP, Schatz DA, Bundy B, Skyler JS, Greenbaum CJ -
Lanthanide-Coordinated Semiconducting Polymer Dots Used for Flow Cytometry and Mass Cytometry.
Angew Chem Int Ed EnglWu X, DeGottardi Q, Wu IC, Yu J, Wu L, Ye F, Kuo CT, Kwok WW, Chiu DT -
B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.
J Exp MedArkatkar T, Du SW, Jacobs HM, Dam EM, Hou B, Buckner JH, Rawlings DJ, Jackson SW -
Understanding and preventing type 1 diabetes through the unique working model of TrialNet.
DiabetologiaBattaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark A, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M -
Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.
J ImmunolBuckner JH, Greenbaum CJ -
Resistance to checkpoint blockade therapy through inactivation of antigen presentation
Nat CommunSade-Feldman M, Jiao YJ, Chen JH, Rooney MS, Barzily-Rokni M, Eliane JP, Bjorgaard SL, Hammond MR, Vitzthum H, Blackmon SM, Frederick DT, Hazar-Rethinam M, Nadres BA, Van Seventer EE, Shukla SA, Yizhak K, Ray JP, Rosebrock D, Adalsteinsson V, Getz GS, Duncan LM, Li B, Corcoran RB, Lawrence DP, Stemmer-Rachamimov A, Boland GM, Landau DA, Flaherty KT, Sullivan RJ, Hacohen N -
Emerging Concepts on Disease-Modifying Therapies in Type 1 Diabetes.
Curr Diab RepGreenbaum CJ, Lord S, VanBuecken DE -
S1P1 deletion differentially affects TH17 and Regulatory T cells.
Sci RepEken A, Duhen R, Singh AK, Fry M, Buckner JH, Kita M, Bettelli E, Oukka M -
DOCK8 regulates fitness and function of regulatory T cells through modulation of IL-2 signaling.
JCI InsightSingh AK, Eken A, Hagin D, Komal K, Bhise G, Shaji A, Arkatkar T, Jackson SW, Bettelli E, Torgerson TR, Oukka M -
The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
J ImmunolMetzler G, Dai X, Thouvenel CD, Khim S, Habib T, Buckner JH, Rawlings DJ -
A novel and rapid method to quantify Treg mediated suppression of CD4 T cells.
J Immunol MethodsLong AE, Tatum M, Mikacenic C, Buckner JH -
Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs.
J Vis ExpSprouse ML, Blahnik G, Lee T, Tully N, Benarjee P, James EA, Redondo MJ, Bettini ML, Bettini M