-
Epithelial cell-derived cytokines: more than just signaling the alarm.
J Clin InvestRoan F, Obata-Ninomiya K, Ziegler SF -
Treg gene signatures predict and measure type 1 diabetes trajectory.
JCI InsightPesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK -
Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.
Curr Diab RepJohnson MB, Cerosaletti K, Flanagan SE, Buckner JH -
Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation.
Proc Natl Acad Sci U S ASchrock DC, Leddon SA, Hughson A, Miller J, Lacy-Hulbert A, Fowell DJ -
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
J ImmunolGlatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E -
Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions".
J Allergy Clin ImmunolDavidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M -
Cell type-specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes.
JCI InsightDufort MJ, Greenbaum CJ, Speake C, Linsley PS -
B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes.
JCI InsightLinsley PS, Greenbaum CJ, Speake C, Long SA, Dufort MJ -
ACC1 determines memory potential of individual CD4(+) T cells by regulating de novo fatty acid biosynthesis.
Nat MetabEndo Y, Onodera A, Obata-Ninomiya K, Koyama-Nasu R, Asou HK, Ito T, Yamamoto T, Kanno T, Nakajima T, Ishiwata K, Kanuka H, Tumes DJ, Nakayama T -
Genetics Coming of Age in Type 1 Diabetes.
Diabetes CareCerolsaletti K, Hao W, Greenbaum CJ -
Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes.
Diabetes CareSims EK, Bahnson HT, Nyalwidhe J, Haataja L, Davis AK, Speake C, DiMeglio LA, Blum J, Morris MA, Mirmira RG, Nadler J, Mastracci TL, Marcovina S, Qian WJ, Yi L, Swensen AC, Yip-Schneider M, Schmidt CM, Considine RV, Arvan P, Greenbaum CJ, Evans-Molina C, T1D Exchange Residual C-peptide Study Group. -
Characterization of regulatory T cells in obese omental adipose tissue in humans.
Eur J ImmunolWu D, Han JM, Yu X, Lam AJ, Hoeppli RE, Pesenacker AM, Huang Q, Chen V, Speake C, Yorke E, Nguyen N, Sampath S, Harris D, Levings MK -
The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Front ImmunolGorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ -
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.
CellRojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL -
Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes.
ScienceAkilesh HM, Buechler MB, Duggan JM, Hahn WO, Matta B, Sun X, Gessay G, Whalen E, Mason M, Presnell SR, Elkon KB, Lacy-Hulbert A, Barnes BJ, Pepper M, Hamerman JA
