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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nature GeneticsRobertson CC, Inshaw JRJ, Onengut-Gumuscu S, Chen WM, Santa Cruz DF, Yang H, Cutler AJ, Crouch DJM, Farber E, Bridges SL Jr, Edberg JC, Kimberly RP, Buckner JH, Deloukas P, Divers J, Dabelea D, Lawrence JM, Marcovina S, Shah AS, Greenbaum CJ, Atkinson MA, Gregersen PK, Oksenberg JR, Pociot F, Rewers MJ, Steck AK, Dunger DB, Type 1 Diabetes Genetics Consortium., Wicker LS, Concannon P, Todd JA, Rich SS -
Pancreatic islet reserve in type 1 diabetes.
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EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update).
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Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?
Frontiers in ImmunologyRodriguez-Calvo T, Christoffersson G, Bender C, von Herrath MG, Mallone R, Kent SC, James EA -
The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients.
PNAS USAPyfrom S, Paneru B, Knox JJ, Cancro MP, Posso S, Buckner JH, Anguera MC -
ICOS signaling limits regulatory T cell accumulation and function in visceral adipose tissue.
The Journal of Experimental MedicineMittelsteadt KL, Hayes ET, Campbell DJ -
Autocrine Hyaluronan Influences Sprouting and Lumen Formation During HUVEC Tubulogenesis In Vitro.
The Journal of Histochemistry and CytochemistryVernon RB, Gooden MD, Chan CK, Workman G, Obika M, Wight TN -
Association of Lipid Mediators With Development of Future Incident Inflammatory Arthritis in an Anti-Citrullinated Protein Antibody-Positive Population.
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Context-Dependent miR-21 Regulation of TLR7-Mediated Autoimmune and Foreign Antigen-Driven Antibody-Forming Cell and Germinal Center Responses.
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Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide.
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Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.
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The many faces of islet antigen-specific CD8 T cells: clues to clinical outcome in type 1 diabetes.
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A Key to T1D Prevention: Screening and Monitoring Relatives as Part of Clinical Care.
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Identifying the 'Achilles heel' of type 1 diabetes.
Clinical and Experimental ImmunologyBattaglia M, Buckner JH, Levings MK, Richardson SJ, Wong FS, Tree TI -
Genome-wide enhancer maps link risk variants to disease genes.
NatureNasser J, Bergman DT, Fulco CP, Guckelberger P, Doughty BR, Patwardhan TA, Jones TR, Nguyen TH, Ulirsch JC, Lekschas F, Mualim K, Natri HM, Weeks EM, Munson G, Kane M, Kang HY, Cui A, Ray JP, Eisenhaure TM, Collins RL, Dey K, Pfister H, Price AL, Epstein CB, Kundaje A, Xavier RJ, Daly MJ, Huang H, Finucane HK, Hacohen N, Lander ES, Engreitz JM
