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High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4+ T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19.
VirusesCords L, Knapp M, Woost R, Schulte S, Kummer S, Ackermann C, Beisel C, Peine S, Johansson AM, Kwok WW, Günther T, Fischer N, Wittner M, Addo MM, Huber S, Schulze Zur Wiesch J -
Immunological Interaction of HLA-DPB1 and Proteinase 3 in ANCA Vasculitis is Associated with Clinical Disease Activity.
J Am Soc NephrolChen D, McInnis E, Wu E, Stember K, Hogan S, Hu Y, Henderson C, Blazek L, Mallal S, Karosiene E, Peters B, Sidney J, James EA, Kwok WW, Jennette JC, Ciavatta DJ, Falk RJ, Free ME -
Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.
Front ImmunolVanderlinden LA, Bemis EA, Seifert J, Guthridge JM, Young KA, Demoruelle MK, Feser M, DeJager W, Macwana S, Mikuls TR, O'Dell JR, Weisman MH, Buckner JH, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Deane KD, James JA, Holers VM, Norris JM -
Impact of BMI on Adverse Events After Laparoscopic and Open Surgery for Rectal Cancer.
J Gastrointest CancerHirpara DH, O'Rourke C, Azin A, Quereshy FA, Wexner SD, Chadi SA -
Chemokines, Soluble PD-L1, and Immune Cell Hyporesponsiveness are Distinct Features of SARS-CoV-2 Critical Illness.
Am J Physiol Lung Cell Mol PhysiolMorrell ED, Bhatraju PK, Sathe NA, Lawson J, Mabrey L, Holton SE, Presnell SR, Wiedeman A, Acosta-Vega C, Mitchem MA, Liu T, Chai XY, Sahi S, Brager C, Orlov M, Sakr SS, Sader A, Lum DM, Koetje N, Garay A, Barnes E, Cromer G, Bray MK, Pipavath S, Fink SL, Evans L, Long SA, West TE, Wurfel MM, Mikacenic C -
Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.
Genome MedClay SM, Schoettler N, Goldstein AM, Carbonetto P, Dapas M, Altman MC, Rosasco MG, Gern JE, Jackson DJ, Im HK, Stephens M, Nicolae DL, Ober C -
STAT1 signaling protects self-reactive T cells from control by innate cells during neuroinflammation.
JCI InsightArbelaez CA, Palle P, Charaix J, Bettelli E -
Safety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine.
N Engl J MedMoreira ED Jr, Kitchin N, Xu X, Dychter SS, Lockhart S, Gurtman A, Perez JL, Zerbini C, Dever ME, Jennings TW, Brandon DM, Cannon KD, Koren MJ, Denham DS, Berhe M, Fitz-Patrick D, Hammitt LL, Klein NP, Nell H, Keep G, Wang X, Koury K, Swanson KA, Cooper D, Lu C, Türeci Ö, Lagkadinou E, Tresnan DB, Dormitzer PR, Şahin U, Gruber WC, Jansen KU, C4591031 Clinical Trial Group -
Emerging role for thymic stromal lymphopoietin-responsive regulatory T cells in colorectal cancer progression in humans and mice.
Sci Transl MedObata-Ninomiya K, de Jesus Carrion S, Hu A, Ziegler SF -
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells.
Nat GenetMouri K, Guo MH, de Boer CG, Lissner MM, Harten IA, Newby GA, DeBerg HA, Platt WF, Gentili M, Liu DR, Campbell DJ, Hacohen N, Tewhey R, Ray JP -
Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination.
Nat CommunGhorbani S, Jelinek E, Jain R, Buehner B, Li C, Lozinski BM, Sarkar S, Kaushik DK, Dong Y, Wight TN, Karimi-Abdolrezaee S, Schenk GJ, Strijbis EM, Geurts J, Zhang P, Ling CC, Yong VW -
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells
Nat GenetMouri K, Guo MH, de Boer CG, Lissner MM, Harten IA, Newby GA, DeBerg HA, Platt WF, Gentili M, Liu DR, Campbell DJ, Hacohen N, Tewhey R, Ray JP -
Single cell transcriptomics and TCR reconstruction reveal CD4 T cell response to MHC-II-restricted APOB epitope in human cardiovascular disease.
Nat Cardiovasc ResSaigusa R, Roy P, Freuchet A, Gulati R, Ghosheh Y, Suthahar SSA, Durant CP, Hanna DB, Kiosses WB, Orecchioni M, Wen L, Wu R, Kuniholm MH, Landay AL, Anastos K, Tien PC, Gange SJ, Kassaye S, Vallejo J, Hedrick CC, Kwok WW, Sette A, Hodis HN, Kaplan RC, Ley K -
CXCL10 and Soluble Programmed Death-Ligand 1 during Respiratory Viral Infections Are Associated with Chronic Lung Allograft Dysfunction in Lung Transplant Recipients.
Am J Respir Cell Mol BiolMorrell ED, Brager C, Ramos KJ, Chai XY, Kapnadak SG, Edelman J, Matute-Bello G, Altemeier WA, Hwang B, Mulligan MS, Bhatraju PK, Wurfel MM, Mikacenic C, Lease ED, Limaye AP, Fisher CE -
Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication.
Sci RepVanderwall ER, Barrow KA, Rich LM, Read DF, Trapnell C, Okoloko O, Ziegler SF, Hallstrand TS, White MP, Debley JS
