Autoimmune Life Blog

Learn the backstory of a discovery that changed our understanding of the immune system and earned a Nobel Prize from Steven Ziegler, PhD.

Explore work from Daniel Campbell, PhD, examining how a cytokine called IL2 could lead to new therapies for autoimmune diseases.

Learn how research led by Jane Buckner, MD, is bringing regulatory T cell-based therapies closer to clinical trials.

Learn more about how his time at BRI helped shape 2025 Rhodes Scholar Shubham Bansal.

Learn how Peter Morawski, PhD, and Hannah DeBerg, PhD, are mapping immune cells in the skin to better understand how they may fight — or fuel — disease.

Allyson Byrd, PhD, and Cate Speake, PhD, are exploring an innovative tool in immunology research. The questions they can ask are limitless.

Early-career scientists play a vital role in BRI’s work. Meet Lucy Li, who is working to answer pressing questions about lupus as part of her MD–PhD program.

Allyson Byrd, PhD, is an expert in the gut microbiome, the study of the tiny organisms that live inside our digestive system. James Lord, MD, PhD, is a gastroenterologist who has studied inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis for more than 20 years.

Learn how CRISPR-Cas9-based genome engineering using adeno-associated virus (AAV) vectors is helping BRI scientists make breakthroughs to study human T cells and explore new treatments for type 1 diabetes, as well as  develop preclinical models to study T cells and B cell

For more than 20 years, Steven Ziegler, PhD, has wondered if an altered version of a protein might play a key role in autoimmune diseases. Now, he finally has the tools to investigate further – and his work could lead to key insights about how and why lupus happens.