Faculty & Scientific Staff
Soo Jung Yang, PhD
Research Assistant Member; Principal Investigator, Yang Lab; Center for Translational Immunology
206.341.8944
Featured Publications
Oct 2024
Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy.
J Autoimmun
Tewari R, Yang SJ, McClain ED, Hu A, Mortensen E, DeSchmidt A, Chen J, Kancharla A, Singh AK, James EA, Burman BE, Siddique A, Rawlings DJ, Patel C, Cerosaletti K, Buckner JH
Feb 2024
GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes.
JCI Insight
Uenishi GI, Repic M, Yam JY, Landuyt A, Saikumar-Lakshmi P, Guo T, Zarin P, Sassone-Corsi M, Chicoine A, Kellogg H, Hunt M, Drow T, Tewari R, Cook PJ, Yang SJ, Cerosaletti K, Schweinoch D, Guiastrennec B, James E, Patel C, Chen TF, Buckner JH, Rawlings DJ, Wickham TJ, Mueller KT
Jul 2023
Dual-locus, dual-HDR editing permits efficient generation of antigen-specific, regulatory T cells with robust suppressive activity.
Mol Ther
Hunt MS, Yang SJ, Mortensen E, Boukhris A, Buckner J, Cook PJ, Rawlings DJ
Oct 2022
Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.
Sci Transl Med
Yang SJ, Singh AK, Drow T, Tappen T, Honaker Y, Barahmand-Pour-Whitman F, Linsley PS, Cerosaletti K, Mauk K, Xiang Y, Smith J, Mortensen E, Cook PJ, Sommer K, Khan I, Liggitt D, Rawlings DJ, Buckner JH
Jun 2020
Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function.
Sci Transl Med
Honaker Y, Hubbard N, Xiang Y, Fisher L, Hagin D, Sommer K, Song Y, Yang SJ, Lopez C, Tappen T, Dam EM, Khan I, Hale M, Buckner JH, Scharenberg AM, Torgerson TR, Rawlings DJ
