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    • Oct 2024

      Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.

      Cells
      Nagy N, Czepiel KS, Kaber G, Stefanovski D, Hargil A, Pennetzdorfer N, Targ R, Reghupaty SC, Wight TN, Vernon RB, Hull-Meichle RL, Marshall P, Medina CO, Martinez H, Kalinowski A, Paladini RD, Garantziotis S, Knowles JW, Bollyky PL
    • Aug 2024

      Response to retention hypothesis as a source of targets for arterial wall-directed therapies to prevent atherosclerosis: A critical review.

      Atherosclerosis
      Kumarapperuma H, Chia ZJ, Malapitan SM, Wight TN, Little PJ, Kamato D
    • Mar 2024

      Versican associates with tumour immune phenotype and limits T cell trafficking via chondroitin sulfate.

      Cancer Res Commun
      Hirani P, McDermott J, Rajeeve V, Cutillas PR, Jones JL, Pennington DJ, Wight TN, Santamaria S, Alonge KM, Pearce OMT
    • Feb 2024

      Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.

      Nat Commun
      Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF
    • Sep 2023

      Inhibition of hyaluronan synthesis prevents β-cell loss in obesity-associated type 2 diabetes.

      Matrix Biol
      Nagy N, Kaber G, Sunkari VG, Marshall PL, Hargil A, Kuipers HF, Ishak HD, Bogdani M, Hull RL, Grandoch M, Fischer JW, McLaughlin TL, Wight TN, Bollyky PL
    • Jul 2023

      Commentary on a Classic JHC Article on Intracellular Hyaluronan Associated with the Mitotic Spindle.

      J Histochem Cytochem
      Evanko SP, Wight TN
    • Jul 2023

      V3: An Enigmatic Isoform of the Proteoglycan Versican.

      Am J Physiol Cell Physiol
      Wight TN, Day AJ, Kang I, Harten IA, Kaber G, Briggs DC, Braun KR, Lemire JM, Kinsella MG, Hinek A, Merrilees MJ
    • Feb 2023

      FOXP3(+) regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues.

      bioRxiv
      Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF
    • Jun 2022

      Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 infections.

      JCI Insight
      Kratochvil MJ, Kaber G, Demirdjian S, Cai PC, Burgener EB, Nagy N, Barlow GL, Popescu M, Nicolls MR, Ozawa MG, Regula DP, Pacheco-Navarro AE, Yang S, de Jesus Perez VA, Karmouty-Quintana H, Peters AM, Zhao B, Buja ML, Johnson PY, Vernon RB, Wight TN, Stanford COVID-19 Biobank Study Group., Milla CE, Rogers AJ, Spakowitz AJ, Heilshorn SC, Bollyky PL
    • May 2022

      Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination.

      Nat Commun
      Ghorbani S, Jelinek E, Jain R, Buehner B, Li C, Lozinski BM, Sarkar S, Kaushik DK, Dong Y, Wight TN, Karimi-Abdolrezaee S, Schenk GJ, Strijbis EM, Geurts J, Zhang P, Ling CC, Yong VW
    • Apr 2022

      Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro.

      Matrix Biol Plus
      Kang I, Hundhausen C, Evanko SP, Malapati P, Workman G, Chan CK, Rims C, Firestein GS, Boyle DL, MacDonald KM, Buckner JH, Wight TN
    • Jan 2022

      Detection of Glycosaminoglycans in Pancreatic Islets and Lymphoid Tissues.

      Methods Mol Biol
      Bogdani M, Simeonovic C, Nagy N, Johnson PY, Chan CK, Wight TN
    • Aug 2021

      Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer.

      Front Oncol
      Hirani P, Gauthier V, Allen CE, Wight TN, Pearce OMT
    • Jun 2021

      Autocrine Hyaluronan Influences Sprouting and Lumen Formation During HUVEC Tubulogenesis In Vitro.

      J Histochem Cytochem
      Vernon RB, Gooden MD, Chan CK, Workman G, Obika M, Wight TN
    • Mar 2021

      The extracellular matrix molecules versican and hyaluronan in urethral and vaginal tissues in stress urinary incontinence.

      Neurourol Urodyn
      Harten IA, Evanko SP, Choe CH, Lee EW, Patel BN, Bogdani M, Wight TN, Lee UJ

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Benaroya Research Institute

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Seattle, WA 98101-2795
(206) 342-6500

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