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    • Jul 2025

      Airway Immune Signatures in Severe and Fatal Infection with COVID-19.

      Am J Respir Cell Mol Biol
      Doni Jayavelu N, Qi JJ, Fourati S, Kheradmand F, Langelier CR, Ehrlich LIR, Diray-Arce J, Hoch A, Kraft M, Becker PM, Altman MC, Montgomery RR
    • Mar 2025

      Reduced Function of the Adaptor SH2B3 Promotes T1D via Altered Cytokine-Regulated, T-Cell-Intrinsic Immune Tolerance.

      Diabetes
      Watson TK, Rosen ABI, Drow T, Medjo JA, MacQuivey MA, Ge Y, Liggitt HD, Grosvenor DA, Dill-McFarland KA, Altman MC, Concannon PJ, Buckner JH, Rawlings DJ, Allenspach EJ
    • Mar 2025

      Dysregulation of airway and systemic interferon responses promotes asthma exacerbations in urban children.

      J Allergy Clin Immunol
      Gaberino CL, Altman MC, Gill MA, Bacharier LB, Gruchalla RS, O'Connor GT, Kumar R, Khurana Hershey GK, Kattan M, Liu AH, Teach SJ, Zoratti EM, Becker PM, Togias A, Visness C, Gern JE, Busse WW, Jackson DJ
    • Mar 2025

      Identification of bronchial epithelial genes associated with type 2 eosinophilic inflammation in asthma.

      J Allergy Clin Immunol
      Esnault S, Dill-McFarland KA, Altman MC, Rosenkranz MA, Jarjour NN, Busse WW
    • Mar 2025

      Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.

      Nat Commun
      Pickering H, Schaenman J, Phan HV, Maguire C, Tsitsiklis A, Rouphael N, Higuita NIA, Atkinson MA, Brakenridge S, Fung M, Messer W, IMPACC Network, Salehi-Rad R, Altman MC, Becker PM, Bosinger SE, Eckalbar W, Hoch A, Doni Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed EF, Langelier CR
    • Mar 2025

      Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping.

      bioRxiv
      Wang K, Nie Y, Maguire C, Syphurs C, Sheen H, Karoly M, Lapp L, Gygi JP, Jayavelu ND, Patel RK, Hoch A, IMPACC Network, Corry D, Kheradmand F, McComsey GA, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, Davis MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Hafler DA, Shaw A, Rahman A, Hough CL, Geng LN, Ozonoff A, Haddad EK, Reed EF, van Bakel H, Kim-Schultz S, Krammer F, Wilson M, Eckalbar W, Bosinger S, Langelier CR, Sekaly RP, Montgomery RR, Maecker HT, Krumholz H, Melamed E, Steen H, Pulendran B, Augustine AD, Cairns CB, Rouphael N, Becker PM, Fourati S, Shannon CP, Smolen KK, Peters B, Kleinstein SH, Levy O, Altman MC, Iwasaki A, Diray-Arce J, Ehrlich LIR, Guan L
    • Mar 2025

      Oncostatin-M Is Produced by Human Eosinophils and Expression Is Increased in Uncontrolled Severe Asthma.

      Allergy
      Esnault S, Bernau K, Floerke HL, Dendooven A, Delaunay E, Dill-McFarland KA, Altman MC, Busse WW, Rosenkranz MA, Tattersall MC, Johansson MW, Labreuche J, Beury D, Sebda S, Dezoteux F, Segard B, Mortuaire G, Staumont-Sallé D, Stoup T, Chenivesse C, Sandbo N, Jarjour NN, Lefèvre G
    • Mar 2025

      Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.

      bioRxiv
      Maguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH, IMPACC Network, Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E
    • Sep 2024

      Clinical and Molecular Analysis of Longitudinal Rhinitis Phenotypes in an Urban Birth Cohort.

      J Allergy Clin Immunol
      Ramratnam SK, Johnson M, Visness CM, Calatroni A, Altman MC, Janczyk T, McCauley KE, Schachtschneider C, Fujimura KE, Fadrosh DW, Lynch SV, Bacharier LB, O'Connor GT, Sandel MT, Kattan M, Wood RA, Gergen PJ, Jackson DJ, Togias A, Gern JE, Childhood Asthma in Urban Settings (CAUSE) network
    • Aug 2024

      Home and school pollutant exposure, respiratory outcomes, and influence of historical redlining.

      J Allergy Clin Immunol
      Jung KH, Argenio KL, Jackson DJ, Miller RL, Perzanowski MS, Rundle AG, Bacharier LB, Busse WW, Cohen RT, Visness CM, Gill MA, Gruchalla RS, Hershey GK, Kado RK, Sherenian MG, Liu AH, Makhija MM, Pillai DK, Rivera-Spoljaric K, Gergen PJ, Altman MC, Sandel MT, Sorkness CA, Kattan M, Lovinsky-Desir S
    • May 2024

      Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations.

      Nat Commun
      Szczesny B, Boorgula MP, Chavan S, Campbell M, Johnson RK, Kammers K, Thompson EE, Cox MS, Shankar G, Cox C, Morin A, Lorizio W, Daya M, Kelada SNP, Beaty TH, Doumatey AP, Cruz AA, Watson H, Naureckas ET, Giles BL, Arinola GA, Sogaolu O, Falade AG, Hansel NN, Yang IV, Olopade CO, Rotimi CN, Landis RC, Figueiredo CA, Altman MC, Kenny E, Ruczinski I, Liu AH, Ober C, Taub MA, Barnes KC, Mathias RA
    • May 2024

      A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy.

      J Allergy Clin Immunol
      Zoratti E, Wood R, Pomés A, da Silva Antunes R, Altman MC, Benson B, Wheatley LM, Cho K, Calatroni A, Little FF, Pongracic J, Makhija M, Khurana Hershey GK, Sherenian MG, Rivera-Spoljaric K, Stokes JR, Gill MA, Gruchalla RS, Chambliss J, Liu AH, Kattan M, Busse PJ, Bacharier LB, Sheehan W, Kim H, Glesner J, Gergen PJ, Togias A, Baucom JL, Visness CM, Sette A, Busse WW, Jackson DJ, Inner-City Asthma and Childhood Asthma in Urban Settings Consortia
    • May 2024

      Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.

      J Clin Invest
      Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK, IMPACC Network, Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L
    • May 2024

      Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.

      Sci Transl Med
      Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, IMPACC Network, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR
    • Mar 2024

      Activated sputum eosinophils associated with exacerbations in children on mepolizumab.

      J Allergy Clin Immunol
      Wilson GE, Knight J, Liu Q, Shelar A, Stewart E, Wang X, Yan X, Sanders J, Visness C, Gill M, Gruchalla R, Liu AH, Kattan M, Hershey GKK, Togias A, Becker PM, Altman MC, Busse WW, Jackson DJ, Montgomery RR, Chupp GL

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Benaroya Research Institute

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