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Identification of immunogenic commensal antigens using phage display.
Nat ProtocVerma S, Kimmel S, Harrison OJ -
A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection.
CellWestfall S, Gentile ME, Olsen TM, Karo-Atar D, Bogza A, Röstel F, Pardy RD, Mandato G, Fontes G, Herbert D, Melichar HJ, Abadie V, Richer MJ, Vinh DC, Koenig JFE, Harrison OJ, Divangahi M, Weis S, Gregorieff A, King IL -
Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection.
J ImmunolLabuda JC, Olsen TM, Verma S, Kimmel S, Edwards TH, Dufort MJ, Harrison OJ -
Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers.
ImmunityVerma S, Dufort MJ, Olsen TM, Kimmel S, Labuda JC, Scharffenberger S, McGuire AT, Harrison OJ -
The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota.
Proc Natl Acad Sci U S AKulalert W, Wells AC, Link VM, Lim AI, Bouladoux N, Nagai M, Harrison OJ, Kamenyeva O, Kabat J, Enamorado M, Chiu IM, Belkaid Y -
Antigen-level resolution of commensal-specific B cell responses enabled by phage-display screening and B cell tetramers.
bioRxivHarrison OJ, et al. -
A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice.
Nat CommunHackstein CP, Costigan D, Drexhage L, Pearson C, Bullers S, Ilott N, Akther HD, Gu Y, FitzPatrick MEB, Harrison OJ, Garner LC, Mann EH, Pandey S, Friedrich M, Provine NM, Uhlig HH, Marchi E, Powrie F, Klenerman P, Thornton EE -
Th17 cells: from gut homeostasis to CNS pathogenesis.
Trends ImmunolBuckner JH, Harrison OJ -
sLRP1'in up retinol keeps the gut SAAfe.
ImmunityLabuda J, Harrison OJ -
Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers.
J Exp MedByrd AL, Liu M, Fujimura KE, Lyalina S, Nagarkar DR, Charbit B, Bergstedt J, Patin E, Harrison OJ, Quintana-Murci L, Mellman I, Duffy D, Albert ML, Milieu Intérieur Consortium. -
Immunity to commensal skin fungi promotes psoriasiform skin inflammation.
Proc Natl Acad Sci U S AHurabielle C, Link VM, Bouladoux N, Han SJ, Merrill ED, Lightfoot YL, Seto N, Bleck CKE, Smelkinson M, Harrison OJ, Linehan JL, Tamoutounour S, Lionakis MS, Kaplan MJ, Nakajima S, Belkaid Y -
Poised for tissue repair.
ScienceHarrison OJ -
Stability and dynamics of the human gut microbiome and its association with systemic immune traits
bioRxivByrd AL, Liu M, Fujimura KE, Lyalina S, Nagarkar DR, Charbit B, Bergstedt J, Patin E, Harrison OJ, Quintana-Murci L, Duffy D, Albert ML, Milieu Intérieur Consortium. -
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury.
ScienceHarrison OJ, Linehan JL, Shih HY, Bouladoux N, Han SJ, Smelkinson M, Sen SK, Byrd AL, Enamorado M, Yao C, Tamoutounour S, Van Laethem F, Hurabielle C, Collins N, Paun A, Salcedo R, O'Shea JJ, Belkaid Y -
c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont.
NatureXu M, Pokrovskii M, Ding Y, Yi R, Au C, Harrison OJ, Galan C, Belkaid Y, Bonneau R, Littman DR
