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HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.
PLoS PathogVingert B, Perez-Patrigeon S, Jeannin P, Lambotte O, Boufassa F, Lemaître F, Kwok WW, Theodorou I, Delfraissy JF, Thèze J, Chakrabarti LA, ANRS EP36 HIV Controllers Study Group -
Reassessing the role of HLA-DRB3 T-cell responses: evidence for significant expression and complementary antigen presentation.
Eur J ImmunolFaner R, James E, Huston L, Pujol-Borrel R, Kwok WW, Juan M -
Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts.
Cancer ResJandus C, Bioley G, Dojcinovic D, Derré L, Baitsch L, Wieckowski S, Rufer N, Kwok WW, Tiercy JM, Luescher IF, Speiser DE, Romero P -
The binding of antigenic peptides to HLA-DR is influenced by interactions between pocket 6 and pocket 9.
J ImmunolJames EA, Moustakas AK, Bui J, Nouv R, Papadopoulos GK, Kwok WW -
Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.
BloodEttinger RA, James EA, Kwok WW, Thompson AR, Pratt KP -
H5N1 strain-specific hemagglutinin CD4+ T cell epitopes restricted by HLA DR4.
VaccineYang J, Gebe JA, Huston L, James EA, Tan V, Yue BB, Nepom GT, Kwok WW -
Visualizing antigen specific CD4+ T cells using MHC class II tetramers.
J Vis ExpJames EA, LaFond R, Durinovic-Belló I, Kwok WW -
Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects.
Eur J ImmunolLong SA, Walker MR, Rieck M, James EA, Kwok WW, Sanda S, Pihoker C, Nepom GT, Buckner JH -
Searching immunodominant epitopes prior to epidemic: HLA class II-restricted SARS-CoV spike protein epitopes in unexposed individuals.
Int ImmunolYang J, James EA, Roti M, Huston L, Gebe JA, Kwok WW -
The anthrax vaccine adsorbed vaccine generates protective antigen (PA)-Specific CD4+ T cells with a phenotype distinct from that of naive PA T cells.
Infect ImmunKwok WW, Yang J, James EA, Bui J, Huston L, Wiesen AR, Roti M -
CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope.
J AutoimmunYang J, Danke N, Roti M, Huston L, Greenbaum CJ, Pihoker C , James EA, Kwok WW -
Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes.
DiabetesJames EA, Kwok WW -
Definition of the peptide binding motif within DRB1*1401 restricted epitopes by peptide competition and structural modeling.
Mol ImmunolJames EA, Moustakas AK, Berger D, Huston L, Papadopoulos GK, Kwok WW -
Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection.
J VirolEbinuma H, Nakamoto N, Li Y, Price DA, Gostick E, Levine BL, Tobias J, Kwok WW, Chang KM -
Searching for borrelial T cell epitopes associated with antibiotic-refractory Lyme arthritis.
Mol ImmunolDrouin EE, Glickstein L, Kwok WW, Nepom GT, Steere AC