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CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring.
ImmunologyYang J, James EA, Sanda S, Greenbaum CJ, Kwok WW -
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
PLoS PathogLindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A -
Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination.
Cancer ResAarntzen EH, De Vries IJ, Lesterhuis WJ, Schuurhuis D, Jacobs JF, Bol K, Schreibelt G, Mus R, De Wilt JH, Haanen JB, Schadendorf D, Croockewit A, Blokx WA, Van Rossum MM, Kwok WW, Adema GJ, Punt CJ, Figdor CG -
Characterization of CD4+ T cell subsets in allergy.
Curr Opin ImmunolWambre E, James EA, Kwok WW -
Allergen-specific CD4+ T cell responses in peripheral blood do not predict the early onset of clinical efficacy during grass pollen sublingual immunotherapy.
Clin Exp AllergyBonvalet M, Moussu H, Wambre E, Ricarte C, Horiot S, Rimaniol AC, Kwok WW, Horak F, de Beaumont O, Baron-Bodo V, Moingeon P -
HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term.
J VirolVingert B, Benati D, Lambotte O, de Truchis P, Slama L, Jeannin P, Galperin M, Perez-Patrigeon S, Boufassa F, Kwok WW, Lemaître F, Delfraissy JF, Thèze J, Chakrabarti LA -
Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).
J ImmunolArlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A -
Frequency of epitope-specific naive CD4(+) T cells correlates with immunodominance in the human memory repertoire.
J ImmunolKwok WW, Tan V, Gillette L, Littell CT, Soltis MA, LaFond RB, Yang J, James EA, DeLong JH -
DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9.
Mol ImmunolChow IT, James EA, Tan V, Moustakas AK, Papadopoulos GK, Kwok WW -
Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy.
J Allergy Clin ImmunolWambre E, DeLong JH, James EA, LaFond RE, Robinson D, Kwok WW -
Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance.
J Allergy Clin ImmunolPalomares O, Rückert B, Jartti T, Kücüksezer UC, Puhakka T, Gomez E, Fahrner HB, Speiser A, Jung A, Kwok WW, Kalogjera L, Akdis M, Akdis CA -
Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence.
J Exp MedSchulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan BE, Streeck H, Aneja J, Reyor LL, Allen TM, Lohse AW, McGovern B, Chung RT, Kwok WW, Kim AY, Lauer GM -
Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue.
PLoS PathogPido-Lopez J, Kwok WW, Mitchell TJ, Heyderman RS, Williams NA -
Human CD8⁺ and CD4⁺ T cell memory to lymphocytic choriomeningitis virus infection.
J VirolKotturi MF, Swann JA, Peters B, Arlehamn CL, Sidney J, Kolla RV, James EA, Akondy RS, Ahmed R, Kwok WW, Buchmeier MJ, Sette A -
Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells.
J ImmunolMattapallil MJ, Silver PB, Mattapallil JJ, Horai R, Karabekian Z, McDowell JH, Chan CC, James EA, Kwok WW, Sen HN, Nussenblatt RB, David CS, Caspi RR
