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Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.
Journal of AutoimmunityAlvarez I, Collado JA, Colobran R, Carrascal M, Ciudad MT, Canals F, James EA, Kwok WW, Gärtner M, Kyewski B, Pujol-Borrell R, Jaraquemada D -
Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis.
Science Translational MedicineCao Y, Goods BA, Raddassi K, Nepom GT, Kwok WW, Love JC, Hafler DA -
Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening.
TuberculosisNayak K, Jing L, Russell RM, Davies DH, Hermanson G, Molina DM, Liang X, Sherman DR, Kwok WW, Yang J, Kenneth J, Ahamed SF, Chandele A, Murali-Krishna K, Koelle DM -
Arginine kinase Pen m 2 as an important shrimp allergen recognized by TH2 cells.
The Journal of Allergy and Clinical ImmunologyRenand A, Newbrough S, Wambre E, DeLong JH, Robinson D, Kwok WW -
Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.
PLoS OneChow IT, Yang J, Gates TJ, James EA, Mai DT, Greenbaum CJ, Kwok WW -
Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.
PNAS USAYang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW -
Circulating Type-1 Anti-Tumor CD4(+) T Cells are Preferentially Pro-Apoptotic in Cancer Patients.
Frontiers in OncologyWesa AK, Mandic M, Taylor JL, Moschos S, Kirkwood JM, Kwok WW, Finke JH, Storkus WJ -
Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.
DiabetesMcGinty JW, Chow IT, Greenbaum CJ, Odegard JM, Kwok WW, James EA -
Immune regulation by intralymphatic immunotherapy with modular allergen translocation MAT vaccine.
AllergyZaleska A, Eiwegger T, Soyer O, van de Veen W, Rhyner C, Soyka MB, Bekpen C, Demiröz D, Treis A, Söllner S, Palomares O, Kwok WW, Rose H, Senti G, Kündig TM, Ozoren N, Jutel M, Akdis CA, Crameri R, Akdis M -
Grass-specific CD4(+) T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy.
Clinical and Experimental AllergyArchila LD, DeLong JH, Wambre E, James EA, Robinson DM, Kwok WW -
Virologic and immunologic evidence of multifocal genital herpes simplex virus 2 infection.
Journal of VirologyJohnston C, Zhu J, Jing L, Laing KJ, McClurkan CM, Klock A, Diem K, Jin L, Stanaway J, Tronstein E, Kwok WW, Huang ML, Selke S, Fong Y, Magaret A, Koelle DM, Wald A, Corey L -
Peptide-induced immune regulation by a promiscuous and immunodominant CD4T-cell epitope of Timothy grass pollen: a role of Cbl-b and Itch in regulation.
ThoraxTill SJ, Raynsford EJ, Reynolds CJ, Quigley KJ, Grzybowska-Kowalczyk A, Saggar LR, Goldstone A, Maillère B, Kwok WW, Altmann DM, Durham SR, Boyton RJ -
Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner.
The Journal of Allergy and Clinical ImmunologyWambre E, DeLong JH, James EA, Torres-Chinn N, Pfützner W, Möbs C, Durham SR, Till SJ, Robinson D, Kwok WW -
Differential CD4+ T-cell responses of allergic and non-allergic subjects to the immunodominant epitope region of the horse major allergen Equ c 1.
ImmunologyKailaanmäki A, Kinnunen T, Kwok WW, Rytkönen-Nissinen M, Randell J, Virtanen T -
Yellow fever vaccination elicits broad functional CD4+ T cell responses that recognize structural and nonstructural proteins.
Journal of VirologyJames EA, LaFond RE, Gates TJ, Mai DT, Malhotra U, Kwok WW