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Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy.
Arthritis & RheumatologyJames EA, Rieck M, Pieper J, Gebe JA, Yue BB, Tatum M, Peda M, Sandin C, Klareskog L, Malmström V, Buckner JH -
Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner.
The Journal of Allergy and Clinical ImmunologyWambre E, DeLong JH, James EA, Torres-Chinn N, Pfützner W, Möbs C, Durham SR, Till SJ, Robinson D, Kwok WW -
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope.
Journal of AutoimmunityDahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT, Reiter Y -
Yellow fever vaccination elicits broad functional CD4+ T cell responses that recognize structural and nonstructural proteins.
Journal of VirologyJames EA, LaFond RE, Gates TJ, Mai DT, Malhotra U, Kwok WW -
CD4+ T cells recognize unique and conserved 2009 H1N1 influenza hemagglutinin epitopes after natural infection and vaccination.
International ImmunologyYang J, James EA, Gates TJ, DeLong JH, LaFond RE, Malhotra U, Kwok WW -
Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB1*08:01 and DRB1*11:01 Is predicted by their structural motifs and correlates with disease risk.
Journal of ImmunologyChow IT, James EA, Gates TJ, Tan V, Moustakas AK, Papadopoulos GK, Kwok WW -
CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring.
ImmunologyYang J, James EA, Sanda S, Greenbaum CJ, Kwok WW -
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
PLoS PathogLindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A -
Characterization of CD4+ T cell subsets in allergy.
Current Opinion in ImmunologyWambre E, James EA, Kwok WW -
Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).
J ImmunolArlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A -
Frequency of epitope-specific naive CD4(+) T cells correlates with immunodominance in the human memory repertoire.
Journal of ImmunologyKwok WW, Tan V, Gillette L, Littell CT, Soltis MA, LaFond RB, Yang J, James EA, DeLong JH -
DRB1*12:01 presents a unique subset of epitopes by preferring aromatics in pocket 9.
Molecular ImmunologyChow IT, James EA, Tan V, Moustakas AK, Papadopoulos GK, Kwok WW -
Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy.
The Journal of Allergy and Clinical ImmunologyWambre E, DeLong JH, James EA, LaFond RE, Robinson D, Kwok WW -
Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.
Diabetes/Metabolism Research and ReviewsJames EA, Mallone R, Schloot NC, Gagnerault MC, Thorpe J, Fitzgerald-Miller L, Reichow J, Wagner R, Pham MN, Jospe N, Lou O, Gottlieb PA, Brooks-Worrell BM, Durinovic-Belló I, T-Cell Workshop Committee, Immunology of Diabetes Society. -
Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative.
Diabetes/Metabolism Research and ReviewsMallone R, Scotto M, Janicki CN, James EA, Fitzgerald-Miller L, Wagner R, Gottlieb P, Thorpe J, Jospe N, Durinovic-Belló I, Boitard C, Lou O, Dayan CM, Wong FS, T-Cell Workshop Committee, Immunology of Diabetes Society