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Aug 2016
Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining.
Nat CommunUchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA -
May 2016
Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity.
Clin Exp AllergyHinz D, Seumois G, Gholami AM, Greenbaum JA, Lane J, White B, Broide DH, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok WW, Peters B, Vijayanand P, Sette A -
Feb 2016
Expanding antigen-specific regulatory networks to treat autoimmunity.
NatureClemente-Casares X, Blanco J, Ambalavanan P, Yamanouchi J, Singha S, Fandos C, Tsai S, Wang J, Garabatos N, Izquierdo C, Agrawal S, Keough MB, Yong VW, James EA, Moore A , Yang Y , Stratmann T , Serra P , Santamaria P -
Jan 2016
Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.
PLoS PathogJames EA, Gates TJ, LaFond RE, Yamamoto S, Ni C, Mai D, Gersuk VH, O'Brien K, Nguyen QA, Zeitner B, Lanteri MC, Norris PJ, Chaussabel D, Malhotra U, Kwok WW -
Nov 2015
T cell epitopes and post-translationally modified epitopes in type 1 diabetes.
Curr Diab RepMcGinty JW, Marré ML, Bajzik V, Piganelli JD, James EA -
Oct 2015
β cell ER stress and the implications for immunogenicity in type 1 diabetes.
Front Cell Dev BiolMarré ML, James EA, Piganelli JD -
Aug 2015
Factor VIII gene variants and inhibitor risk in African American hemophilia A patients.
BloodGunasekera D, Ettinger RA, Nakaya Fletcher S, James EA, Liu M, Barrett JC, Withycombe J, Matthews DC, Epstein MS, Hughes RJ, Pratt KP, Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators. -
Jun 2015
Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.
J AutoimmunAlvarez I, Collado JA, Colobran R, Carrascal M, Ciudad MT, Canals F, James EA, Kwok WW, Gärtner M, Kyewski B, Pujol-Borrell R, Jaraquemada D -
Nov 2014
Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.
PLoS OneChow IT, Yang J, Gates TJ, James EA, Mai DT, Greenbaum CJ, Kwok WW -
Oct 2014
Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.
Proc Natl Acad Sci U S AYang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW -
Sep 2014
Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.
DiabetesMcGinty JW, Chow IT, Greenbaum CJ, Odegard JM, Kwok WW, James EA -
Jul 2014
Grass-specific CD4(+) T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy.
Clin Exp AllergyArchila LD, DeLong JH, Wambre E, James EA, Robinson DM, Kwok WW -
Jul 2014
Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy.
Arthritis RheumatolJames EA, Rieck M, Pieper J, Gebe JA, Yue BB, Tatum M, Peda M, Sandin C, Klareskog L, Malmström V, Buckner JH -
Mar 2014
Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner.
J Allergy Clin ImmunolWambre E, DeLong JH, James EA, Torres-Chinn N, Pfützner W, Möbs C, Durham SR, Till SJ, Robinson D, Kwok WW -
Dec 2013
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope.
J AutoimmunDahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT, Reiter Y
