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Apr 2019
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
EBioMedicineJames JA, Chen H, Young KA, Bemis EA, Seifert J, Bourn RL, Deane KD, Demoruelle MK, Feser M, O'Dell JR, Weisman MH, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Harley JB, Robinson W, Hafler DA, O'Connor KC, Buckner JH, Guthridge JM, Norris JM, Holers VM -
Mar 2019
Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.
Curr Diab RepJohnson MB, Cerosaletti K, Flanagan SE, Buckner JH -
Mar 2019
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
J ImmunolGlatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E -
Jan 2019
The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Front ImmunolGorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ -
Dec 2018
IL-6: a cytokine at the crossroads of autoimmunity.
Curr Opin ImmunolJones BE, Maerz MD, Buckner JH -
Sep 2018
Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.
Front ImmunolDam EM, Maier AC, Hocking AM, Carlin J, Ng B, Buckner JH -
Sep 2018
Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction.
Nat Rev RheumatolHolers VM, Demoruelle MK, Kuhn KA, Buckner JH, Robinson WH, Okamoto Y, Norris JM, Deane KD -
Aug 2018
Circulating integrin alpha4/beta7+ lymphocytes targeted by vedolizumab have a pro-inflammatory phenotype.
Clin ImmunolLord JD, Long SA, Shows DM, Thorpe J, Schwedhelm K, Chen J, Kita M, Buckner JH -
Aug 2018
Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.
J AutoimmunPieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V -
Jul 2018
Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
DiabetesGreenbaum CJ, Speake C, Krischer J, Buckner JH, Gottlieb PA, Schatz DA, Herold KC, Atkinson MA -
Mar 2018
Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".
Sci ImmunolCarmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ -
Nov 2017
B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.
J Exp MedArkatkar T, Du SW, Jacobs HM, Dam EM, Hou B, Buckner JH, Rawlings DJ, Jackson SW -
Nov 2017
Understanding and preventing type 1 diabetes through the unique working model of TrialNet.
DiabetologiaBattaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark A, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M -
Nov 2017
Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.
J ImmunolBuckner JH, Greenbaum CJ -
Oct 2017
S1P1 deletion differentially affects TH17 and Regulatory T cells.
Sci RepEken A, Duhen R, Singh AK, Fry M, Buckner JH, Kita M, Bettelli E, Oukka M
