-
Apr 2021
Early Prognostic Indicators of Subsequent Hospitalization in Patients with Mild COVID-19.
J Clin MedYlescupidez A, Rips A, Bahnson HT, Speake C, Verma P, Hocking AM, Buckner JH, Malhotra U -
Apr 2021
Combination therapy in recent-onset type 1 diabetes.
Lancet Diabetes EndocrinolLong SA, Speake C -
Feb 2021
The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity.
J Clin InvestBolouri H, Speake C, Skibinski D, Long SA, Hocking AM, Campbell DJ, Hamerman JA, Malhotra U, Buckner JH, Benaroya Research Institute COVID-19 Research Team. -
Nov 2020
Sensitive detection of multiple islet autoantibodies in type 1 diabetes using small sample volumes by agglutination-PCR.
PLoS OneCortez FJ, Gebhart D, Robinson PV, Seftel D, Pourmandi N, Owyoung J, Bertozzi CR, Wilson DM, Maahs DM, Buckingham BA, Mills JR, Roforth MM, Pittock SJ, McKeon A, Page K, Wolf WA, Sanda S, Speake C, Greenbaum CJ, Tsai CT -
Aug 2020
Innate immune stimulation of whole blood reveals IFN-1 hyper-responsiveness in type 1 diabetes.
DiabetologiaRodrigues KB, Dufort MJ, Llibre A, Speake C, Rahman MJ, Bondet V, Quiel J, Linsley PS, Greenbaum CJ, Duffy D, Tarbell KV -
Aug 2020
Response to Comment on So et al. Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody-Positive Individuals. Diabetes Care 2020;43:913-917.
Diabetes CareSo M, O'Rourke C, Bahnson HT, Greenbaum CJ, Speake C -
Jul 2020
Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells.
JCI InsightNeiman D, Gillis D, Piyanzin S, Cohen D, Fridlich O, Moss J, Zick A, Oron T, Sundberg F, Forsander G, Skog O, Korsgren O, Levy-Khademi F, Arbel D, Hashavia S, Shapiro AMJ, Speake C, Greenbaum CJ, Hosford J, Posgai AL, Atkinson MA, Glaser B, Schatz DA, Shemer R, Dor Y -
Jul 2020
Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01.
DiabetesArribas-Layton D, Guyer P, Delong T, Dang M, Chow IT, Speake C, Greenbaum CJ, Kwok WW, Baker RL, Haskins K, James EA -
May 2020
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes.
Nat ImmunolAbdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B -
Apr 2020
Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody-Positive Individuals.
Diabetes CareSo M, O'Rourke C, Bahnson HT, Greenbaum CJ, Speake C -
Mar 2020
Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates.
DiabetologiaBogdani M, Speake C, Dufort MJ, Johnson PY, Larmore MJ, Day AJ, Wight TN, Lernmark A, Greenbaum CJ -
Mar 2020
Circulating Unmethylated Insulin DNA As a Biomarker of Human Beta Cell Death: A Multi-laboratory Assay Comparison.
J Clin Endocrinol MetabSpeake C, Ylescupidez A, Neiman D, Shemer R, Glaser B, Tersey SA, Usmani-Brown S, Clark P, Wilhelm JJ, Bellin MD, Herold KC, Mirmira RG, Dor Y, Evans-Molina C -
Mar 2020
Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis.
DiabetesShapiro MR, Wasserfall CH, McGrail SM, Posgai AL, Bacher R, Muir A, Haller MJ, Schatz DA, Wesley JD, von Herrath M, Hagopian WA, Speake C, Atkinson MA, Brusko TM -
Jan 2020
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.
J Clin InvestWiedeman AE, Muir VS, Rosasco MG, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James EA, Linsley PS, Long SA -
Jan 2020
In-vivo assessment of T cell kinetics in individuals at risk for type 1 diabetes.
Clin Exp ImmunolHao W, Bahnson HT, Speake C, Cerosaletti K, Greenbaum CJ
