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Synchronous immune alterations mirror clinical response during allergen immunotherapy.
J Allergy Clin ImmunolRenand A, Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR -
Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.
J Clin InvestVeatch JR, Lee SM, Fitzgibbon M, Chow IT, Jesernig B, Schmitt T, Kong YY, Kargl J, Houghton AM, Thompson JA, McIntosh M, Kwok WW, Riddell SR -
Single-Cell Tracking Reveals a Role for Pre-Existing CCR5+ Memory Th1 Cells in the Control of Rhinovirus-A39 After Experimental Challenge in Humans.
J Infect DisMuehling LM, Turner RB, Brown KB, Wright PW, Patrie JT, Lahtinen SJ, Lehtinen MJ, Kwok WW, Woodfolk JA -
C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc Natl Acad Sci U S AWang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S -
Lanthanide-Coordinated Semiconducting Polymer Dots Used for Flow Cytometry and Mass Cytometry.
Angew Chem Int Ed EnglWu X, DeGottardi Q, Wu IC, Yu J, Wu L, Ye F, Kuo CT, Kwok WW, Chiu DT -
αS1-Casein elucidate major T-cell responses in cow's milk allergy.
J Allergy Clin ImmunolArchila LD, Khan FS, Bhatnagar N, Robinson D, Farrington ML, Kwok WW -
A phenotypically and functionally distinct human TH2 cell subpopulation is associated with allergic disorders.
Sci Transl MedWambre E, Bajzik V, DeLong JH, O'Brien K, Nguyen QA, Speake C, Gersuk VH, DeBerg HA, Whalen E, Ni C, Farrington M, Jeong D, Robinson D, Linsley PS, Vickery BP, Kwok WW -
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
J ImmunolCerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS -
Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to β Cell Antigens Are Focused on a Unique Set of Epitopes.
J ImmunolYang J, Wen X, Xu H, Torres-Chinn N, Speake C, Greenbaum CJ, Nepom GT, Kwok WW -
Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
DiabetesMichels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M -
Tetramer-Guided Epitope Mapping: A Rapid Approach to Identify HLA-Restricted T-Cell Epitopes from Composite Allergens.
Methods Mol BiolArchila LL, Kwok WW -
Circulating Memory CD4+ T Cells Target Conserved Epitopes of Rhinovirus Capsid Proteins and Respond Rapidly to Experimental Infection in Humans.
J ImmunolMuehling LM, Mai DT, Kwok WW, Heymann PW, Pomés A, Woodfolk JA -
Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.
Sci Transl MedCho JL, Ling MF, Adams DC, Faustino L, Islam SA, Afshar R, Griffith JW, Harris RS, Ng A, Radicioni G, Ford AA, Han AK, Xavier R, Kwok WW, Boucher R, Moon JJ, Hamilos DL, Kesimer M, Suter MJ, Medoff BD, Luster AD -
A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis.
Arthritis RheumatolScholz E, Mestre-Ferrer A, Daura X, García-Medel N, Carrascal M, James EA, Kwok WW, Canals F, Alvarez I -
Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining.
Nat CommunUchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA
