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Jul 2020
Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis.
JCI InsightCarmona-Rivera C, Carlucci PM, Goel RR, James EA, Brooks SR, Rims C, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ -
Jun 2020
Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function.
Sci Transl MedHonaker Y, Hubbard N, Xiang Y, Fisher L, Hagin D, Sommer K, Song Y, Yang SJ, Lopez C, Tappen T, Dam EM, Khan I, Hale M, Buckner JH, Scharenberg AM, Torgerson TR, Rawlings DJ -
Jun 2020
Notch signalling drives synovial fibroblast identity and arthritis pathology.
NatureWei K, Korsunsky I, Marshall JL, Gao A, Watts GFM, Major T, Croft AP, Watts J, Blazar PE, Lange JK, Thornhill TS, Filer A, Raza K, Donlin LT, Accelerating Medicines Partnership Rheumatoid Arthritis & Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Buckner JH, Siebel C, Buckley C, Raychaudhuri, Brenner M -
Apr 2020
Multiparameter Analysis Identifies Heterogeneity in Knee Osteoarthritis Synovial Responses.
Arthritis RheumatolLabinsky H, Panipinto PM, Ly KA, Khuat DK, Madarampalli B, Mahajan V, Clabeaux J, MacDonald K, Verdin PJ, Buckner JH, Noss EH -
Dec 2019
Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.
J RheumatolBerens HM, Polinski KJ, Mikuls TR, Khatter S, August J, Visser A, Mahler M, Weisman MH, O'Dell JR, Keating RM, Buckner JH, Gregersen PK, Norris JM, Holers VM, Deane KD, Demoruelle MK -
Jun 2019
Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.
DiabetesHabib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum CJ, Buckner JH, Type 1 Diabetes TrialNet Study Group. -
Apr 2019
Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.
J ImmunolStathopoulos P, Chastre A, Waters P, Irani S, Fichtner ML, Benotti ES, Guthridge JM, Seifert J, Nowak RJ, Buckner JH, Holers VM, James JA, Hafler DA, O'Connor KC -
Apr 2019
Coordinated Induction of Antimicrobial Response Factors in Systemic Lupus Erythematosus.
Front ImmunolAyyappan P, Harms RZ, Buckner JH, Sarvetnick NE -
Apr 2019
Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.
Arthritis RheumatolRims C, Uchtenhagen H, Kaplan MJ, Carmona-Rivera C, Carlucci P, Mikecz K, Markovics A, Carlin J, Buckner JH, James EA -
Apr 2019
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
EBioMedicineJames JA, Chen H, Young KA, Bemis EA, Seifert J, Bourn RL, Deane KD, Demoruelle MK, Feser M, O'Dell JR, Weisman MH, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Harley JB, Robinson W, Hafler DA, O'Connor KC, Buckner JH, Guthridge JM, Norris JM, Holers VM -
Mar 2019
Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.
Curr Diab RepJohnson MB, Cerosaletti K, Flanagan SE, Buckner JH -
Mar 2019
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
J ImmunolGlatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E -
Jan 2019
The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Front ImmunolGorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ -
Dec 2018
IL-6: a cytokine at the crossroads of autoimmunity.
Curr Opin ImmunolJones BE, Maerz MD, Buckner JH -
Sep 2018
Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.
Front ImmunolDam EM, Maier AC, Hocking AM, Carlin J, Ng B, Buckner JH
