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May 2014
Low HERV-K(C4) copy number is associated with type 1 diabetes.
DiabetesMason MJ, Speake C, Gersuk VH, Nguyen QA, O'Brien KK, Odegard JM, Buckner JH, Greenbaum CJ, Chaussabel D, Nepom GT -
Dec 2013
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope.
J AutoimmunDahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT, Reiter Y -
Dec 2013
Anti-cytokine therapies in T1D: Concepts and strategies.
Clin ImmunolNepom GT, Ehlers M, Mandrup-Poulsen T -
Dec 2013
Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet Diabetes EndocrinolRigby MR, DiMeglio LA, Rendell MS, Felner EI, Dostou JM, Gitelman SE, Patel CM, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Moran A, Russell WE, Pinckney A, Keyes-Elstein L, Howell M, Aggarwal S, Lim N, Phippard D, Nepom GT, McNamara J, Ehlers MR, T1DAL Study Team. -
May 2013
Immunological biomarkers: catalysts for translational advances in autoimmune diabetes.
Clin Exp ImmunolAhmed ST, Akirav E, Bradshaw E, Buckner JH, McKinney E, Quintana FJ, Waldron-Lynch F, Nepom GT -
Apr 2013
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines.
ImmunityObermoser G, Presnell S, Domico K, Xu H, Wang Y, Anguiano E, Thompson-Snipes L, Ranganathan R, Zeitner B, Bjork A, Anderson D, Speake C, Ruchaud E, Skinner J, Alsina L, Sharma M, Dutartre H, Cepika A, Israelsson E, Nguyen P, Nguyen QA, Harrod AC, Zurawski SM, Pascual V, Ueno H, Nepom GT, Quinn C, Blankenship D, Palucka K, Banchereau J, Chaussabel D -
Jan 2013
IL-10 induction from implants delivering pancreatic islets and hyaluronan.
J Diabetes ResBollyky PL, Vernon RB, Falk BA, Preisinger A, Gooden MD, Nepom GT, Gebe JA -
Oct 2012
A functional framework for interpretation of genetic associations in T1D.
Curr Opin ImmunolNepom GT, Buckner JH -
Jul 2012
T cell autoreactivity in the transplant milieu.
Am J TransplantMatthis J, Nepom GT -
Mar 2012
MHC class II tetramers.
J ImmunolNepom GT -
Mar 2012
Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration.
Matrix BiolEvanko SP, Potter-Perigo S, Bollyky PL, Nepom GT, Wight TN -
Feb 2012
Self-reactive human CD4 T cell clones form unusual immunological synapses.
J Exp MedSchubert DA, Gordo S, Sabatino JJ Jr, Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, Wucherpfennig KW -
Jan 2012
Ultra-sensitive detection of rare T cell clones.
J Immunol MethodsRobins H, Desmarais C, Matthis J, Livingston R, Andriesen J, Reijonen H, Carlson C, Nepom GT, Yee C , Cerosaletti K -
Jan 2012
Reversal of diabetes in mice with a bioengineered islet implant incorporating a type I collagen hydrogel and sustained release of vascular endothelial growth factor.
Cell TransplantVernon RB, Preisinger A, Gooden MD, D'Amico LA, Yue BB, Bollyky PL, Kuhr CS, Hefty TR, Nepom GT, Gebe JA -
Jan 2012
Immune-directed therapy for type 1 diabetes at the clinical level: the Immune Tolerance Network (ITN) experience.
Rev Diabet StudEhlers MR, Nepom GT