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Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain.
Cancer Immunol ResLongino NV, Yang J, Iyer JG, Ibrani D, Chow IT, Laing KJ, Campbell VL, Paulson KG, Kulikauskas RM, Church CD, James EA, Nghiem P, Kwok WW, Koelle DM -
Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study.
Front ImmunolSpeake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hansen B, von Herrath M, Greenbaum CJ -
Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes.
Sci AdvChow IT, Gates TJ, Papadopoulos GK, Moustakas AK, Kolawole EM, Notturno RJ, McGinty JW, Torres-Chinn N, James EA, Greenbaum CJ, Nepom GT, Kwok WW -
Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes.
DiabetesZhao LP, Papadopoulos GK, Kwok WW, Xu B, Kong M, Moustakas AK, Bondinas GP, Carlsson A, Elding-Larsson H, Ludvigsson J, Marcus C, Persson M, Samuelsson U, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A -
HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules.
Sci RepAckermann C, Smits M, Woost R, Eberhard JM, Peine S, Kummer S, Marget M, Kuntzen T, Kwok WW, Lohse AW, Jacobs T, Boettler T, Schulze Zur Wiesch J -
Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity.
Cell Host MicrobeRuff WE, Dehner C, Kim WJ, Pagovich O, Aguiar CL, Yu AT, Roth AS, Vieira SM, Kriegel C, Adeniyi O, Mulla MJ, Abrahams VM, Kwok WW, Nussinov R, Erkan D, Goodman AL, Kriegel MA -
Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense.
J ImmunolHung SC, Hou T, Jiang W, Wang N, Qiao SW, Chow IT, Liu X, van der Burg SH, Koelle DM, Kwok WW, Sollid LM, Mellins ED -
Der p 1-specific regulatory T-cell response during house dust mite allergen immunotherapy.
AllergyBoonpiyathad T, Sokolowska M, Morita H, Rückert B, Kast JI, Wawrzyniak M, Sangasapaviliya A, Pradubpongsa P, Fuengthong R, Thantiworasit P, Sirivichayakul S, Kwok WW, Ruxrungtham K, Akdis M, Akdis CA -
How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci ImmunolWang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S -
Identification of Human Antigen-Specific CD4+ T-Cells with Peptide-MHC Multimer Technologies.
Methods Mol BiolKong YY, Kwok WW -
Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.
Cell ImmunolBlahnik G, Uchtenhagen H, Chow IT, Speake C, Greenbaum CJ, Kwok WW, James EA -
DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.
J ImmunolJames EA, Gillette L, Durinovic-Belló I, Speake C, Bondinas GP, Moustakas AK, Greenbaum CJ, Papadopoulos GK, Kwok WW -
A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize.
Front ImmunolYang J, Jing L, James EA, Gebe JA, Koelle DM, Kwok WW -
Peanut-specific T cell responses in patients with different clinical reactivity.
PLoS OneBirrueta G, Tripple V, Pham J, Manohar M, James EA, Kwok WW, Nadeau KC, Sette A, Peters B, Schulten V -
Ratiometric Barcoding for Mass Cytometry.
Anal ChemWu X, DeGottardi Q, Wu IC, Wu L, Yu J, Kwok WW, Chiu DT