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The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity.
The Journal of Clinical InvestigationBolouri H, Speake C, Skibinski D, Long SA, Hocking AM, Campbell DJ, Hamerman JA, Malhotra U, Buckner JH, Benaroya Research Institute COVID-19 Research Team. -
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.
CellRodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Hale M, Rathe J, Stokes C, Wrenn S, Fiala B, Carter L, Hamerman JA, King NP, Gale M Jr, Campbell DJ, Rawlings DJ, Pepper M -
Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function.
Journal of ImmunologyHayes ET, Hagan CE, Khoryati L, Gavin MA, Campbell DJ -
Transcriptomic Profiling of Human Effector and Regulatory T Cell Subsets Identifies Predictive Population Signatures.
ImmunohorizonsHöllbacher B, Duhen T, Motley S, Klicznik MM, Gratz IK, Campbell DJ -
Circulating TFH cells as a marker for early therapeutic intervention in T1D.
Nature ImmunologyBettelli E, Campbell DJ -
An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice.
Science ImmunologyKhoryati L, Pham MN, Sherve M, Kumari S, Cook K, Pearson J, Bogdani M, Campbell DJ, Gavin MA -
A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin.
Scientific ReportsKlicznik MM, Benedetti A, Gail LM, Varkhande SR, Holly R, Laimer M, Stoecklinger A, Sir A, Reitsamer R, Neuper T, Horejs-Hoeck J, Rosenblum MD, Campbell DJ, Murauer EM, Gratz IK -
Resident memory T cells show that it is never too late to change your ways.
Nature ImmunologyGratz IK, Campbell DJ -
Rapid Light-Dependent Degradation of Fluorescent Dyes in Formulated Serum-Free Media.
ImmunohorizonsMorawski PA, Motley SJ, Campbell DJ -
Peptidase inhibitor 16 identifies a human regulatory T-cell subset with reduced FOXP3 expression over the first year of recent onset type 1 diabetes.
European Journal of ImmunologyHope CM, Welch J, Mohandas A, Pederson S, Hill D, Gundsambuu B, Eastaff-Leung N, Grosse R, Bresatz S, Ang G, Papademetrios M, Zola H, Duhen T, Campbell D, Brown CY, Krumbiegel D, Sadlon T, Couper JJ, Barry SC, Campbell DJ -
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals.
Science ImmunologyKlicznik MM, Morawski PA, Höllbacher B, Varkhande SR, Motley SJ, Kuri-Cervantes L, Goodwin E, Rosenblum MD, Long SA, Brachtl G, Duhen T, Betts MR, Campbell DJ, Gratz IK -
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
Journal of ImmunologyGlatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E -
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.
CellRojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL -
Cutting Edge: Dynamic Expression of Id3 Defines the Stepwise Differentiation of Tissue-Resident Regulatory T Cells.
Journal of ImmunologySullivan JM, Höllbacher B, Campbell DJ -
B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation.
The Journal of Experimental MedicineSingh MD, Ni M, Sullivan JM, Hamerman JA, Campbell DJ
