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Mediators of monocyte chemotaxis and matrix remodeling are associated with the development of fibrosis in patients with COVID-19.
medRxivHolton SE, Mitchem M, Pipavath S, Morrell ED, Bhatraju PK, Hamerman JA, Speake C, Malhotra U, Wurfel MM, Ziegler S, Mikacenic C -
Association of Trauma Molecular Endotypes With Differential Response to Transfusion Resuscitation Strategies.
JAMA SurgeryThau MR, Liu T, Sathe NA, O'Keefe GE, Robinson BRH, Bulger E, Wade CE, Fox EE, Holcomb JB, Liles WC, Stanaway IB, Mikacenic C, Wurfel MM, Bhatraju PK, Morrell ED -
Alveolar Biomarker Profiles in Subphenotypes of the Acute Respiratory Distress Syndrome.
Critical Care MedicineSathe NA, Morrell ED, Bhatraju PK, Fessler MB, Stapleton RD, Wurfel MM, Mikacenic C -
Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity.
Crit Care ExplorBhatraju PK, Morrell ED, Stanaway IB, Sathe NA, Srivastava A, Postelnicu R, Green R, Andrews A, Gonzalez M, Kratochvil CJ, Kumar VK, Hsiang TY, Gale M Jr, Anesi GL, Wyles D, Broadhurst MJ, Brett-Major D, Mukherjee V, Sevransky JE, Landsittel D, Hung C, Altemeier WA, Gharib SA, Uyeki TM, Cobb JP, Liebler JM, Crosslin DR, Jarvik GP, Segal LN, Evans L, Mikacenic C, Wurfel MM -
Plasma Interleukin-6 Predicts Clinical Decline After Completion of Dexamethasone Therapy in Severe COVID-19.
Critical Care ExplorationsMabrey FL, Bhatraju PK, Morrell ED, Zelnick LR, Sathe NA, O'Connor NG, Mikacenic C, Martin TR, Liles WC, Wurfel MM -
Chemokines, Soluble PD-L1, and Immune Cell Hyporesponsiveness are Distinct Features of SARS-CoV-2 Critical Illness.
American Journal of Physiology. Lung Cellular and Molecular PhysiologyMorrell ED, Bhatraju PK, Sathe NA, Lawson J, Mabrey L, Holton SE, Presnell SR, Wiedeman A, Acosta-Vega C, Mitchem MA, Liu T, Chai XY, Sahi S, Brager C, Orlov M, Sakr SS, Sader A, Lum DM, Koetje N, Garay A, Barnes E, Cromer G, Bray MK, Pipavath S, Fink SL, Evans L, Long SA, West TE, Wurfel MM, Mikacenic C -
CXCL10 and Soluble Programmed Death-Ligand 1 during Respiratory Viral Infections Are Associated with Chronic Lung Allograft Dysfunction in Lung Transplant Recipients.
American Journal of Respiratory Cell and Molecular BiologyMorrell ED, Brager C, Ramos KJ, Chai XY, Kapnadak SG, Edelman J, Matute-Bello G, Altemeier WA, Hwang B, Mulligan MS, Bhatraju PK, Wurfel MM, Mikacenic C, Lease ED, Limaye AP, Fisher CE -
Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness.
Critical Care MedicineMikacenic C, Bhatraju P, Robinson-Cohen C, Kosamo S, Fohner AE, Dmyterko V, Long SA, Cerosaletti K, Calfee CS, Matthay MA, Walley KR, Russell JA, Christie JD, Meyer NJ, Christiani DC, Wurfel MM -
MAP2K2 Delays Recovery in Murine Models of Acute Lung Injury and Associates with ARDS Outcome.
American Journal of Respiratory Cell and Molecular BiologyGong KQ, Mikacenic C, Long ME, Frevert C, Birkland TP, Charron J, Gharib SA, Manicone AM -
Relationships Between Age, Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), and Mortality Among Critically Ill Adults: A Cohort Study.
ShockSathe NA, Bhatraju PK, Mikacenic C, Morrell ED, Mabrey FL, Liles WC, Wurfel MM -
Differences between Children and Adults with COVID-19: It's Right under Our Nose.
American Journal of Respiratory Cell and Molecular BiologyMorrell ED, Mikacenic C -
Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019.
Critical Care ExplorationsMabrey FL, Morrell ED, Bhatraju PK, Sathe NA, Sakr SS, Sahi SK, West TE, Mikacenic C, Wurfel MM -
Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations.
JCI InsightHelms L, Marchiano S, Stanaway IB, Hsiang TY, Juliar BA, Saini S, Zhao YT, Khanna A, Menon R, Alakwaa F, Mikacenic C, Morrell ED, Wurfel MM, Kretzler M, Harder JL, Murry CE, Himmelfarb J, Ruohola-Baker H, Bhatraju PK, Gale M Jr, Freedman BS -
The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.
Journal of ImmunologyAllenspach EJ, Shubin NJ, Cerosaletti K, Mikacenic C, Gorman JA, MacQuivey MA, Rosen ABI, Timms AE, Wray-Dutra MN, Niino K, Liggitt D, Wurfel MM, Buckner JH, Piliponsky AM, Rawlings DJ -
Clinical presentation, complications, and outcomes of hospitalized COVID-19 patients in an academic center with a centralized palliative care consult service.
Health Science ReportsBaker SM, Leedy DJ, Klafter JA, Zhang Y, Secrest KM, Osborn TR, Cheng RK, Judson SD, Merel SE, Mikacenic C, Bhatraju PK, Liles WC