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Profiling Associations Between IGHG-FCGR Ligand-Receptor Interactions and Disease Progression From Stage 1 and 2 to Stage 3 Type 1 Diabetes
DiabetesLue Ping Zhao, George K Papadopoulos , Jay S Skyler, Hemang M Parikh, William W Kwok, Terry P Lybrand, George P Bondinas, Antonis K Moustakas, Ruihan Wang , Chul-Woo Pyo , Wyatt C Nelson , Daniel E Geraghty, Åke Lernmark -
T-cell responses against CD19-targeted CAR T cells varnimcabtagene autoleucel (ARI-0001): implications for immune response and therapy outcomes
J Immunother CancerAriadna Bartoló-Ibars, Andrea Aran, Alexandra M Johansson, Valentín Ortiz-Maldonado, Nela Klein-González, Anna Alonso-Saladrigues, Eddie James, Alvaro Urbano-Ispizua, Susana Rives, Julio Delgado, Europa Azucena González-Navarro, William W Kwok, Manel Juan -
Profiling associations of interactive ligand-receptors (HLA class I and KIR gene products) with the progression to type 1 diabetes among seroconverted participants
DiabetologiaLue Ping Zhao, George K Papadopoulos , Benjamin J McFarland, Jay S Skyler, Hemang M Parikh, William W Kwok, Terry P Lybrand, George P Bondinas, Antonis K Moustakas, Ruihan Wang , Chul-Woo Pyo , Wyatt C Nelson , Daniel E Geraghty, Åke Lernmark -
Ara h 2105-124-Specific TH2A Cells Drive Peanut Allergy in DRB1*15:01 Individuals: A Detailed Epitope Analysis
Clin Exp AllergyRebecca A Gomez, Jue Hou, Vivian H Gersuk, I-Ting Chow, Mary L Farrington, David Robinson, William W Kwok -
Two DRB3 residues predictively associate with the progression to type 1 diabetes among DR3 carriers
JCI InsightLue Ping Zhao, George K Papadopoulos , Jay S Skyler, William W Kwok, George P Bondinas, Antonis K Moustakas, Ruihan Wang , Chul-Woo Pyo , Wyatt C Nelson , Daniel E Geraghty, Åke Lernmark -
Longitudinal single cell profiling of epitope specific memory CD4+ T cell responses to recombinant zoster vaccine
Nat CommunXiaomin Wen, Alex K Hu, Emily S Ford, David M Koelle, William W Kwok, +Presnell SR -
Single cell profiling of circulating autoreactive CD4 T cells from patients with autoimmune liver diseases suggests tissue imprinting.
Nat CommunCardon A, Guinebretière T, Dong C, Gil L, Ado S, Gavlovsky PJ, Braud M, Danger R, Schultheiß C, Doméné A, Paul-Gilloteaux P, Chevalier C, Bernier L, Judor JP, Fourgeux C, Imbert A, Khaldi M, Bardou-Jacquet E, Elkrief L, Lannes A, Silvain C, Schnee M, Tanne F, Vavasseur F, Brusselle L, Brouard S, Kwok WW, Mosnier JF, Lohse AW, Poschmann J, Binder M, Gournay J, Conchon S, Milpied P, Renand A -
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis.
RMD OpenTurcinov S, Sharma RK, De Vries C, Cîrciumaru A, Gerstner C, Mathsson-Alm L, Raposo B, Dubnovitsky A, Rönnblom L, Kwok WW, Chemin K, Malmström V, Hensvold A -
Antigen-specific T-cell frequency and phenotype mirrors disease activity in DRB1*04:04+ rheumatoid arthritis patients.
Clin Exp ImmunolRims C, Uchtenhagen H, Brooks K, Ng B, Posso SE, Carlin J, Kwok WW, Buckner JH, James EA -
Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers.
DiabetologiaZhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A -
Oral Insulin Delay of Stage 3 Type 1 Diabetes Revisited in HLA DR4-DQ8 Participants in the TrialNet Oral Insulin Prevention Trial (TN07).
Diabetes CareZhao LP, Papadopoulos GK, Skyler JS, Parikh HM, Kwok WW, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A -
T-cell receptor sequencing in interrogating antigen-specific T-cell responses to foreign and self-antigens.
J Allergy Clin ImmunolJohansson AM, Kwok WW -
HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07).
Diabetes CareZhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark A -
Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study.
J Clin Endocrinol MetabEttinger RA, Buitinga M, Vandamme C, Afonso G, Gomez R, Arribas-Layton D, Bissenova S, Speake C, Reijonen H, Kinnunen T, Overbergh L, Mallone R, Kwok WW, James EA -
Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4(+) T-cell response with pre-primed responses directed against common cold coronaviruses.
Front ImmunolWestphal T, Mader M, Karsten H, Cords L, Knapp M, Schulte S, Hermanussen L, Peine S, Ditt V, Grifoni A, Addo MM, Huber S, Sette A, Lütgehetmann M, Pischke S, Kwok WW, Sidney J, Schulze Zur Wiesch J
