Cardiology
Benaroya Research Institute and Virginia Mason Medical Center conduct clinical trials to discover new treatments and approaches to cardiovascular disease. Research studies are conducted for a variety of heart diseases including heart valve disease, coronary artery disease and atrial fibrillation.
Clinical Research Studies in Cardiology
We have ongoing clinical research studies in multiple areas of cardiovascular disease. Studies labeled as “Enrolling” are actively accepting new participants, while studies labeled as “Closed to Enrollment” are still active but no longer seeking new participants.
Please email Cardiology Clinical Research or call (206) 287-6260 for more information.
- A randomized, double-blind, placebo-controlled, multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease (Victorion-2 PREVENT)
Learn more at Clinicaltrials.gov
Principal Investigator: Drew Baldwin, MD
Status: Enrolling
- DELIVER INSIGHTS IN HYPERTROPHIC CARDIOMYOPATHY AND OBSERVATIONAL OUTCOMES IN REAL WORLD (DISCOVER-HCM): UNITED STATES PROSPECTIVE REGISTRY STUDY
Learn more at Clinicaltrials.gov
Principal Investigator: Mariko Harper, MD
Status: Enrolling- Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP II TR)A prospective, multicenter, randomized, controlled pivotal trial to evaluate the safety and effectiveness of transcatheter tricuspid valve repair with the Edwards PASCA
A prospective, multicenter, randomized, controlled pivotal trial to evaluate the safety and effectiveness of transcatheter tricuspid valve repair with the Edwards PASCAL Transcatheter Valve Repair System and optimal medical therapy (OMT) compared to OMT alone in patients with tricuspid regurgitation.
Learn more at Clinicaltrials.gov
Principal Investigator: Ming Zhang, MD
Status: Enrolling- Edwards Transcatheter Valve Tricuspid Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy using a Novel Device.
Learn more at Clinicaltrials.gov
Principal Investigator: Ming Zhang, MD
Status: Enrolling- Irrigated Radio Frequency Ablation to Terminate Non-Paroxysmal Atrial Fibrillation (Terminate AF Study)
Learn more at Clinicaltrials.gov
Principal Investigator: Robert Moraca, MD
Status: Enrolling- Percutaneous or Surgical Mitral Valve REpair in PAtients with Primary Mitral Regurgitation whose mitral valve has been determined to be suitable for correction by MV repair surgery.
Learn more at Clinicaltrials.gov
Principal Investigator: Ming Zhang, MD
Status: Enrolling- Post-Approval Study Protocol for Hybrid Convergent of Epicardial RF Ablation and Endocardial Ablation for the Treatment of Symptomatic Long Standing Persistent AF.
Learn more at Clinicaltrials.gov
Principal Investigator: Robert Moraca, MD
Status: Enrolling- A phase III randomised, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with preserved Ejection Fraction (HFpEF) EMPEROR
Learn more at Clinicaltrials.gov
Principal Investigator: Sarah Weiss, MD
Status: Closed to Enrollment- DETERMINE-preserved-Dap0agliflozin EffecT on ExeRcise capacity using 6 MINutE walk test in patients with heart failure with preserved ejection fraction.
Learn more at Clinicaltrials.gov
Principal Investigator: Sarah Weiss, MD
Status: Closed to Enrollment
Clinical Trials Unit Team Leadership

Leslie Stevens
Clinical Trials Unit Team Members

Amelia Johnson

Daniel Machuca

Jin Yoon
