
Innovation Fund Spotlight: State-of-the-Art Genome Editing To Understand Disease and Develop New Therapies
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Clues into Crohn's: Exploring Why the Immune System Attacks Beneficial Bacteria
Your gut is home to a huge community of bacteria called the microbiome. Some bacteria are good, some are bad — and some might hold the key to understanding an inflammatory bowel disease (IBD) like Crohn’s disease and ulcerative colitis.

Inside BRI’s Gut Immunity Program
To most people, the gut is just a part of your body that helps digest food.

Could medicines for inflammatory bowel disease help fight type 1 diabetes?
Among the many mysteries of autoimmune diseases, we know one thing for sure: These diseases are connected. They often occur when immune cells called T cells mistakenly attack healthy tissue — say the pancreas in type 1 diabetes (T1D) or the gut in inflammatory bowel disease (IBD).

Understanding What Causes IBD
James Lord, MD, PhD, has a simple way of explaining the immune system. “It’s not a homogenous pot of stew,” he says. “It’s a carefully orchestrated dance, and doing the right thing at the right time is critical. But it’s very hard to predict the choreography.”

COVID-19 / Coronavirus: 14 Things People with Autoimmune Disease Should Know
We’re all hearing that people with underlying conditions and immune deficiencies are more susceptible to COVID-19. It’s natural for people with autoimmune disease to wonder what this means for them.

New Gut Immunity Program Takes on IBD, COVID-19 and More
Most people don’t spend much time thinking about their gut. They know it starts at their mouth and ends at their rectum — and they hope it stays in working order. They might even know it includes the gut microbiome, millions of bacteria in your large intestine.

Maybe a Baby? 7 Things Docs Want You to Know About Being Pregnant With an Autoimmune Disease
Making the choice to have a baby can be complicated for any prospective parent. When you have an autoimmune disease, that decision can seem even more complex. You may wonder how pregnancy will impact your disease, and whether your disease will affect your baby.

Pursuing a Revolution in IBD Treatment
Treatment options for inflammatory bowel disease (IBD) have been limited for most of Elisa Boden, MD’s career. Until a few years ago, she and her colleagues – including James Lord, MD, PhD, and Michael Chiorean, MD – have had only a few types of medications to treat IBD.

What Should I Eat? Understanding the Relationship Between Diet and IBD
Recently diagnosed Inflammatory Bowel Disease (IBD) patients often ask: did a certain food cause my disease, and can another food cure it?

New Hope In IBD Clinical Research
Exciting and innovative new treatments for inflammatory bowel diseases (IBD), which includes Crohn’s disease and ulcerative colitis, are now being offered in clinical research trials at Virginia Mason supported by BRI.